2004
DOI: 10.1016/j.jpba.2004.03.018
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Polarographic behavior of cephalexin and its determination in pharmaceuticals and human serum

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Cited by 16 publications
(17 citation statements)
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“…Cephalexin is let to react with a known excess of NBS in acidic media [20][21][22] . The unreacted NBS found in excess over cephalexin is quantified by adding p-anisidine solution ( Figure 1) and monitoring the absorbance of the solution at λ max =522 nm.…”
Section: Resultsmentioning
confidence: 99%
“…Cephalexin is let to react with a known excess of NBS in acidic media [20][21][22] . The unreacted NBS found in excess over cephalexin is quantified by adding p-anisidine solution ( Figure 1) and monitoring the absorbance of the solution at λ max =522 nm.…”
Section: Resultsmentioning
confidence: 99%
“…These include chromatographic methods [5][6][7][8][9], fluorometry [10][11][12], flow injection analysis [13,14], atomic absorption [15] and electroanalytical methods [16]. Limited spectrophotometric techniques are presented for the determination of cephalexin [17][18][19][20].…”
Section: Introductionmentioning
confidence: 99%
“…Methods have been reported for determination of CF [9,10] or conjugated residues of CF [3] in milk. Electroanalytical techniques have been used to determine other cephalosporins, such as cefpodoxime proxetil [11], ceftazidime [12], cephalothin [13], cefminox [14], cefetamet-Na [15], cephalexin [16], cefaclor [17], ceftriaxone [18], cefixime [19], and cefepime [20], providing sensitivity equivalent to that of HPLC techniques. Most cephalosporins are electroactive by virtue of reduction of the (D 3 ) double bond of the cephem nucleus and possibly because of the presence of reducible substituents at the C 7 or C 3 positions in the molecule.…”
Section: Introductionmentioning
confidence: 99%