Polidocanol injection decreases the bleeding rate after colon polypectomy: a propensity score analysis

Facciorusso, Antonio; Maso, M. Di; Antonino, Matteo; Prete, Valentina Del; Pañella, C.; Barone, M.; Muscatiello, Nicola

doi:10.1016/j.gie.2015.01.003

Cited by 28 publications

(15 citation statements)

References 26 publications

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“…The predictive values were then used to obtain a 1-to-2 match by using the nearest neighbor matching within a specified caliper distance, defined as 0.2 of the standard deviation of the logit of the propensity score. [36,37]. Therefore, patients whose propensity score could not be matched due to a greater caliper distance were excluded.…”

Section: Discussionmentioning

confidence: 99%

Comparison between Y90 Radioembolization Plus Sorafenib and Y90 Radioembolization alone in the Treatment of Hepatocellular Carcinoma: A Propensity Score Analysis

Facciorusso

Bargellini²,

Cela

et al. 2020

Cancers

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Background: Adjuvant sorafenib may enhance the efficacy of transarterial radioembolization with yttrium-90 in hepatocellular carcinoma patients. The aim of this study is to assess the efficacy and safety of radioembolization plus sorafenib in comparison to radioembolization alone. Methods: Out of 175 hepatocellular carcinoma (HCC) patients treated with radioembolization between 2011 and 2018, after propensity score matching, two groups were compared: a group of 45 patients that underwent radioembolization while being on sorafenib (Group 1) and a second group of 90 patients that underwent radioembolization alone (Group 2). Results: Baseline characteristics of the two groups were well balanced concerning liver function and tumor burden. No significant differences in survival outcomes were identified (median overall survival 10 vs. 10 months; p = 0.711), median progression-free survival 6 vs. 7 months (p = 0.992) in Group 1 and Group 2). The objective response rate in Group 1 vs. Group 2 was 45.5% vs. 42.8% (p = 1) according to mRECIST. No differences in toxicity nor in liver decompensation rates were registered. Conclusions: The association of sorafenib does not prolong survival nor delay progression in patients treated with radioembolization. Liver toxicity does not differ among the two therapeutic schemes.

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Section: Discussionmentioning

confidence: 99%

Comparison between Y90 Radioembolization Plus Sorafenib and Y90 Radioembolization alone in the Treatment of Hepatocellular Carcinoma: A Propensity Score Analysis

Facciorusso

Bargellini²,

Cela

et al. 2020

Cancers

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“…They are absolutely right in claiming the retrospective nature of our study as a limitation, which is the reason why we performed a complex propensity score caliper analysis. 2 Furthermore, the single-center noncontemporary design of the report stands for a homogenous treatment strategy and surveillance protocol; therefore, we do not see particular sources of selection bias in our study.…”

Section: Use Of Polidocanol In Colon Polypectomymentioning

confidence: 94%

“…Electrosurgery is the most commonly used, but often misunderstood, technology. 2 A rigorous effort should be made to use correct and consistent electrosurgery terminology while designing and publishing those studies.…”

Section: Electrosurgery In Gastrointestinal Endoscopy: Terminology Mamentioning

confidence: 99%

Use of polidocanol in colon polypectomy

Muscatiello

Facciorusso

2016

Gastrointestinal Endoscopy

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“…Thus, there were patients for whom the propensity score could not be matched because of a greater caliper distance and these subjects were excluded from further analysis. As suggested by Austin, a caliper of width equal to 0.2 of the standard deviation of the logit of the propensity score was used, as this value has been found to minimize the mean squared error of the estimated treatment effect [ 27 , 28 ].…”

Section: Methodsmentioning

confidence: 99%

Efficacy and Safety of Non-Anesthesiologist Administration of Propofol Sedation in Endoscopic Ultrasound: A Propensity Score Analysis

et al. 2020

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In spite of promising preliminary results, evidence supporting the use of non-anesthesiologist-administered propofol sedation (NAAP) in endoscopic ultrasound (EUS) procedures is still limited. The aim of this manuscript was to examine the safety and efficacy of NAAP as compared to anesthesiologist-administered propofol sedation in EUS procedures performed in a referral center. Out of 832 patients referred to our center between 2016 and 2019, after propensity score matching two groups were compared: 305 treated with NAAP and 305 controls who underwent anesthesiologist-administered propofol sedation. The primary outcome was the rate of major complications. The median age was 67 years and the proportion of patients with comorbidities was 31.8% in both groups. One patient in each group (0.3%) experienced a major complication, whereas minor complications were observed in 13 patients in the NAAP group (4.2%) and 10 patients in the control group (3.2%; p = 0.52). Overall pain during the procedure was 2.3 ± 1 in group 1 and 1.8 ± 1 in group 2 (p = 0.67), whereas pain/discomfort upon awakening was rated as 1 ± 0.5 in both groups (p = 0.72). NAAP is safe and effective even in advanced EUS procedures. Further randomized-controlled trials (RCTs) are warranted to confirm these findings.

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Polidocanol injection decreases the bleeding rate after colon polypectomy: a propensity score analysis

Cited by 28 publications

References 26 publications

Comparison between Y90 Radioembolization Plus Sorafenib and Y90 Radioembolization alone in the Treatment of Hepatocellular Carcinoma: A Propensity Score Analysis

Comparison between Y90 Radioembolization Plus Sorafenib and Y90 Radioembolization alone in the Treatment of Hepatocellular Carcinoma: A Propensity Score Analysis

Use of polidocanol in colon polypectomy

Efficacy and Safety of Non-Anesthesiologist Administration of Propofol Sedation in Endoscopic Ultrasound: A Propensity Score Analysis

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