Poliomyelitis outbreak in Zambia

Mpabalwani, Evans; Monze, Mwaka; Saijo, Masakuni; Terunuma, Hiroshi; Luo, Na

doi:10.1016/s0140-6736(96)91123-x

Cited by 5 publications

(5 citation statements)

References 6 publications

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“…1991; van Niekerk et al. 1994; Mpabalwani et al. 1996), our findings support WHO recommendations that poliovirus infection in endemic areas can be prevented by conducting mass vaccination campaigns in addition to the routine programme.…”

Section: Discussionsupporting

confidence: 83%

Mass vaccination campaigns to eradicate poliomyelitis in Madagascar: oral poliovirus vaccine increased immunity of children who missed routine programme

Andrianarivelo

Boisier

Rabarijaona

et al. 2001

Tropical Med Int Health

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SummaryTo assess the impact of mass vaccination campaigns using oral poliovirus vaccine (OPV) in Madagascar, serum neutralizing antibodies and geometrical mean titres (GMTs) to poliovirus were measured among 472 children aged up to 59 months, before and after the mass campaign, regardless of their previous history of routine vaccination. In this study, overall coverage with three routine and two mass campaign OPV doses was 69.9 and 93.4%, respectively. Seroprevalences to all poliovirus types were signi®cantly higher after the mass campaign among the children who were not vaccinated through routine programme: 67.5% vs. 90.2% (P < 0.001) for type 1; 66.7% vs. 95.1% (P < 0.001) for type 2; and 55.3% vs. 82.9% (P < 0.001) for type 3. Geometrical mean titres to all poliovirus types also signi®cantly increased after the mass campaign among the same study group: 34.5 vs. 238.9 (P < 0.001) for type 1; 35.1 vs. 402.6 (P < 0.001) for type 2; and 13.3 vs. 92.6 (P < 0.001) for type 3. Post-mass campaign seroprevalences and GMTs for poliovirus, especially types 1 and 3, among children who received up to two routine and two mass campaign OPV doses were signi®cantly higher than pre-mass campaign seroprevalences among children who received three routine OPV doses. Reasons for lack of adherence to the vaccination programme and the mass campaign are discussed. The ®ndings strongly support the WHO strategy of conducting mass campaign in all endemic countries. However, as the mass campaign strategy now has been discontinued, it is crucial to increase the routine coverage and to improve acutē accid paralysis surveillance in order to ful®l the goal of poliomyelitis eradication.keywords eradication, Madagascar, mass vaccination campaigns, poliomyelitis, seroprevalence correspondence M. Rakoto

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Section: Discussionsupporting

confidence: 83%

Mass vaccination campaigns to eradicate poliomyelitis in Madagascar: oral poliovirus vaccine increased immunity of children who missed routine programme

Andrianarivelo

Boisier

Rabarijaona

et al. 2001

Tropical Med Int Health

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“…Similarly, other reports in Africa revealed Wild poliovirus can replicate in well-immunized persons without causing clinical disease and spread to susceptible individuals by two routes: fecal-oral and nasopharyngeal (Ghendon & Robertson 1994). Outbreaks, due to poliovirus type 1, in Namibia van Niekerk et al, 6 and in Zambia Mpabalwani et al, 7 have shown that even high vaccination coverage through routine administration of OPV may be inadequate to provide protection against outbreaks of paralytic poliomyelitis. In Bombay, India Deshpande et al, 8 reported silent transmission of wild poliovirus in 8.2% of the studied population and in 4.4% of fully vaccinated children in Ibadan, Nigeria.…”

Section: Discussionmentioning

confidence: 99%

Isolation and molecular characterization of polio virus isolates from apparently healthy children in maiduguri metropolis

Talle¹

2018

ATROA

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“…C'est ainsi que Kabue et al [6], en République démocra-tique du Congo, ont rapporté 33 % de cas de poliomyélite paralytique chez les enfants ayant reçu au moins 4 doses de VPO. Il en est de même en Namibie [16] et en Zambie [17] où il y a eu plusieurs épidémies de poliomyélite paralytique malgré leur fort taux de couverture vaccinale.…”

Section: Discussionunclassified

Paralysie flasque aiguë chez l’enfant au Bénin : aspects topographiques et étiologiques

Alagnidé

Kpadonou

Moevi

et al. 2015

Journal de Réadaptation Médicale : Pratique et Formation en Méd

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Poliomyelitis outbreak in Zambia

Cited by 5 publications

References 6 publications

Mass vaccination campaigns to eradicate poliomyelitis in Madagascar: oral poliovirus vaccine increased immunity of children who missed routine programme

Mass vaccination campaigns to eradicate poliomyelitis in Madagascar: oral poliovirus vaccine increased immunity of children who missed routine programme

Isolation and molecular characterization of polio virus isolates from apparently healthy children in maiduguri metropolis

Paralysie flasque aiguë chez l’enfant au Bénin : aspects topographiques et étiologiques

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