Considering their focus on participation and sustainable tourism promotion, ecomuseums can play a crucial role in the sociocultural development of local areas. Through three exploratory case studies of Italian ecomuseums located in the Emilia-Romagna region, this study shows the emergence of three different profiles of ecomuseum development strategies: they relate to the sustainable tourism, the cultural districts, and the holistic approach to sociocultural development. These kinds of strategic profiles not only emerge in opposition to each other but can also overlap and appear jointly within different situations of ecomuseums. The final aim of this work is to reflect on the applicability of management tools to support the implementation of these strategic aspects, especially in the current scenario, in which new perspectives are emerging about the role of communities in interpreting and enhancing their tangible and intangible cultural heritage in relation to sustainable tourism and local development linked to cultural and natural heritage preservation and promotion.