2019
DOI: 10.3390/polym11091506
|View full text |Cite
|
Sign up to set email alerts
|

Poly-L-lysine as an Effective and Safe Desquamation Inducer of Urinary Bladder Epithelium

Abstract: Induced desquamation of urinary bladder epithelial cells, also called urothelial cells, is frequently used in studies of bladder epithelial regeneration and also in treating recurrent bacterial cystitis. Positively charged polymer chitosan is known to cause large-scale desquamation of terminally differentiated urothelial cells called umbrella cells. Aiming to compare the desquamation ability of another polycation poly-L-lysine, we studied the effect of this polymer on the functional and structural integrity of… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2020
2020
2024
2024

Publication Types

Select...
2
1

Relationship

1
2

Authors

Journals

citations
Cited by 3 publications
(1 citation statement)
references
References 25 publications
(48 reference statements)
0
1
0
Order By: Relevance
“…However, after bacterial infection or injury, which causes the disruption of tight junctions and desquamation of urothelial cells, proliferative activity and differentiation are rapidly induced, consequentially leading to rapid structural and functional regeneration [7]. For this reason, various chemicals have been used to induce urothelial injury and to study its regeneration or drug diffusion into the bladder stroma [5,13,[20][21][22].…”
Section: Introductionmentioning
confidence: 99%
“…However, after bacterial infection or injury, which causes the disruption of tight junctions and desquamation of urothelial cells, proliferative activity and differentiation are rapidly induced, consequentially leading to rapid structural and functional regeneration [7]. For this reason, various chemicals have been used to induce urothelial injury and to study its regeneration or drug diffusion into the bladder stroma [5,13,[20][21][22].…”
Section: Introductionmentioning
confidence: 99%