Poly(vinyl alcohol) gel ultrasound phantom with durability and visibility of internal flow

Funamoto, Kenichi; Yamashita, Osamu; Hayase, Toshiyuki

doi:10.1007/s10396-014-0560-x

Cited by 15 publications

(10 citation statements)

References 38 publications

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“…Solidification was done by keeping the samples overnight at -20 degrees Celsius, resulting in a transparent hydrogel. The solvent was washed out by submerging the sample in MilliQ water and replacing it everyday for 3 days (Cha et al, 1992;Funamoto et al, 2014). The measured thickness of 10%, 15% and 20% PVA were about 12.4 mm, 10.6 mm and 10.5 mm, respectively.…”

Section: Materials Preparationmentioning

confidence: 99%

Acoustic characterization of tissue-mimicking materials for ultrasound perfusion imaging research

Chen

Pollet

Panfilova

et al. 2022

Ultrasound in Medicine & Biology

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Materials with well-characterized acoustic properties are of great interest for the development of tissue-mimicking phantoms with designed (micro)vasculature networks. These represent a useful means for controlled in-vitro experiments to validate perfusion imaging methods such as Doppler and contrast-enhanced ultrasound (CEUS) imaging. In this work, acoustic properties of seven tissue-mimicking phantom materials at different concentrations of their compounds and five phantom case materials are characterized and compared at room temperature. The goal of this research is to determine the most suitable phantom and case material for ultrasound perfusion imaging experiments. The measurements show a wide range in speed of sound varying from 1057 to 1616 m/s, acoustic impedance varying from 1.09 to 1.71 £ 10 6 kg/m 2 s, and attenuation coefficients varying from 0.1 to 22.18 dB/cm at frequencies varying from 1 MHz to 6 MHz for different phantom materials. The nonlinearity parameter B/A varies from 6.1 to 12.3 for most phantom materials. This work also reports the speed of sound, acoustic impedance and attenuation coefficient for case materials. According to our results, polyacrylamide (PAA) and polymethylpentene (TPX) are the optimal materials for phantoms and their cases, respectively. To demonstrate the performance of the optimal materials, we performed power Doppler ultrasound imaging of a perfusable phantom, and CEUS imaging of that phantom and a perfusion system. The obtained results can assist researchers in the selection of the most suited materials for in-vitro studies with ultrasound imaging.

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Section: Materials Preparationmentioning

confidence: 99%

Acoustic characterization of tissue-mimicking materials for ultrasound perfusion imaging research

Chen

Pollet

Panfilova

et al. 2022

Ultrasound in Medicine & Biology

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“…Different materials can be used to fabricate the phantom model. For example, to test a guidewire or a catheter behavior, phantom’s materials used in the literature include polyvinyl alcohol (PVA), 102 PVA-hydrogel (PVA-H), 38 , 80 , 103 PVA-H and silicone (high transparency), 104 and PVA-cryogel 105 …”

Section: Resultsmentioning

confidence: 99%

Navigation of guidewires and catheters in the body during intervention procedures: a review of computer-based models

et al. 2018

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Guidewires and catheters are used during minimally invasive interventional procedures to traverse in vascular system and access the desired position. Computer models are increasingly being used to predict the behavior of these instruments. This information can be used to choose the right instrument for each case and increase the success rate of the procedure. Moreover, a designer can test the performance of instruments before the manufacturing phase. A precise model of the instrument is also useful for a training simulator. Therefore, to identify the strengths and weaknesses of different approaches used to model guidewires and catheters, a literature review of the existing techniques has been performed. The literature search was carried out in Google Scholar and Web of Science and limited to English for the period 1960 to 2017. For a computer model to be used in practice, it should be sufficiently realistic and, for some applications, real time. Therefore, we compared different modeling techniques with regard to these requirements, and the purposes of these models are reviewed. Important factors that influence the interaction between the instruments and the vascular wall are discussed. Finally, different ways used to evaluate and validate the models are described. We classified the developed models based on their formulation into finite-element method (FEM), mass-spring model (MSM), and rigid multibody links. Despite its numerical stability, FEM requires a very high computational effort. On the other hand, MSM is faster but there is a risk of numerical instability. The rigid multibody links method has a simple structure and is easy to implement. However, as the length of the instrument is increased, the model becomes slower. For the level of realism of the simulation, friction and collision were incorporated as the most influential forces applied to the instrument during the propagation within a vascular system. To evaluate the accuracy, most of the studies compared the simulation results with the outcome of physical experiments on a variety of phantom models, and only a limited number of studies have done face validity. Although a subset of the validated models is considered to be sufficiently accurate for the specific task for which they were developed and, therefore, are already being used in practice, these models are still under an ongoing development for improvement. Realism and computation time are two important requirements in catheter and guidewire modeling; however, the reviewed studies made a trade-off depending on the purpose of their model. Moreover, due to the complexity of the interaction with the vascular system, some assumptions have been made regarding the properties of both instruments and vascular system. Some validation studies have been reported but without a consistent experimental methodology.

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“…The variation in flow phantom ultrasound lies in their respective designs. Two types of flow phantoms are commonly used-wall-less [24,25] and wall flow phantoms [24,26]. Wall-less phantoms use a tissue-mimicking material shaped to mimic the vessel lumen…”

Section: Flow Phantommentioning

confidence: 99%

Tissue-Mimicking Material Fabrication and Properties for Multiparametric Ultrasound Phantoms: A Systematic Review

Jawli,

Aldehani,

Nabi

et al. 2024

Bioengineering

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Medical imaging has allowed for significant advancements in the field of ultrasound procedures over the years. However, each imaging modality exhibits distinct limitations that differently affect their accuracy. It is imperative to ensure the quality of each modality to identify and eliminate these limitations. To achieve this, a tissue-mimicking material (TMM) phantom is utilised for validation. This study aims to perform a systematic analysis of tissue-mimicking materials used for creating ultrasound phantoms. We reviewed 234 studies on the use of TMM phantoms in ultrasound that were published from 2013 to 2023 from two research databases. Our focus was on studies that discussed TMMs’ properties and fabrication for ultrasound, elastography, and flow phantoms. The screening process led to the selection of 16 out of 234 studies to include in the analysis. The TMM ultrasound phantoms were categorised into three groups based on the solvent used; each group offers a broad range of physical properties. The water-based material most closely aligns with the properties of ultrasound. This study provides important information about the materials used for ultrasound phantoms. We also compared these materials to real human tissues and found that PVA matches most of the human tissues the best.

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Poly(vinyl alcohol) gel ultrasound phantom with durability and visibility of internal flow

Abstract: A durable PVA gel ultrasound phantom with visibility of the internal flow was developed.

Cited by 15 publications

References 38 publications

Acoustic characterization of tissue-mimicking materials for ultrasound perfusion imaging research

Acoustic characterization of tissue-mimicking materials for ultrasound perfusion imaging research

Navigation of guidewires and catheters in the body during intervention procedures: a review of computer-based models

Tissue-Mimicking Material Fabrication and Properties for Multiparametric Ultrasound Phantoms: A Systematic Review

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