Poly(vinyl alcohol) Membranes Cross‐linked with Maleic Anhydride and 2,5‐Furandicarboxylic Acid: Conventional Heating and Microwave Irradiation

Salgado‐Chavarría, David; Palacios‐Alquisira, Joaquín

doi:10.1002/slct.202000564

Cited by 6 publications

(2 citation statements)

References 38 publications

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“…Often, PVA has been cross‐linked by carboxylic acids of different types like mono‐, di‐, tri‐, and polycarboxylic acids and also by its derivatives as acid anhydrides and acid chlorides. Formic acid [ 31 ] has been used as monocarboxylic acid whereas a large number of dicarboxylic acids such as oxalic acid, [ 64 ] malonic acid, [ 65 ] succinic acid, [ 50 ] glutaric acid, [ 55 ] adipic acid, [ 66 ] malic acid, [ 67 ] fumaric acid, [ 5 ] MA, [ 68 ] tartaric acid, [ 69 ] suberic acid, [ 6 ] terephthalic acid, [ 6 ] 4‐sulfopthalic acid, [ 70 ] sulfosuccinic acid (SSA), [ 61,71 ] and furandicarboxylic acid [ 72 ] have been used as cross‐linkers. Being nontoxic and inexpensive chemical, CA [ 53,56,73 ] is the most favorable tricarboxylic acid cross‐linking agent, though in this series, acotinic acid [ 48 ] has been also used by some researchers.…”

Section: Various Carboxylic Acids Used As Cross‐linking Agentmentioning

confidence: 99%

A review on carboxylic acid cross‐linked polyvinyl alcohol: Properties and applications

Gautam

Warkar

Ahmad

et al. 2021

Polymer Engineering & Sci

104

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Polyvinyl alcohol (PVA) is a nontoxic, biodegradable, and biocompatible polymer and has been used extensively in various fields. Indeed, important features of PVA such as its film-forming ability, high tensile strength and flexibility, high viscosity, solvent tolerance ability, thermostable nature have made it vital and drawn the attention of scientific community. However, being a watersoluble polymer, some chemical modifications are required to alter this property of PVA. Cross-linking is the most attractive and widely used method to change the properties of PVA to make it more valuable material. Different carboxylic acids have already been used for PVA cross-linking in various applications such as pervaporation, reverse osmosis (RO), wound dressing, drug delivery, and fuel cells. However, a comprehensive study on structure-property correlation of carboxylic acids as PVA cross-linker is not available. In this review, different available studies on carboxylic acid cross-linked PVA are summarized and are used to develop structure-property correlations of carboxylic acids as cross-linker on the properties of cross-linked PVA. Advantages and limitations of different carboxylic acids as PVA cross-linker are also summarized for various fields such as tissue engineering, wound dressing, drug delivery, fuel cell/ solid polymer electrolyte, pervaporation, desalination and RO solid polymer electrolytes, and food packaging.

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Section: Various Carboxylic Acids Used As Cross‐linking Agentmentioning

confidence: 99%

A review on carboxylic acid cross‐linked polyvinyl alcohol: Properties and applications

Gautam

Warkar

Ahmad

et al. 2021

Polymer Engineering & Sci

104

View full text Add to dashboard Cite

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“…As seen in a previous work (Salgado-Chavarría and Palacios-Alquisira, 2020), water was used as a solvent for this reaction, but before starting the cross-linking process, the solvent evaporated at room temperature for 24 h, then, the reaction is performed as a solid-state polymerization, which, in other words, is solvent free. These types of reactions are considered as the ideal situation, since the risk of hazard is reduced, and solvents are avoided.…”

Section: Safer Solvents and Auxiliariesmentioning

confidence: 99%

Problem-Based Learning Approach to Review the Principles of Green Chemistry Applied to a Polycondensation Reaction

Salgado‐Chavarría

Palacios‐Alquisira

2021

SEI

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Science Education International ¦ Volume 32 ¦ Issue 2 107 ORIGINAL ARTICLE INTRODUCTION The problem-based learning (PBL) methodology is a student-centered approach that is related to the learning process that occurs when students deal with real world problems, while working in teams to find and develop a solution, with teachers/instructors acting as facilitators (Nagarajan and Overton, 2019). Some elements seem to be common to PBL: Learning is student centered (as mentioned before), problems are structured and authentic, teachers act as advisors, and students work in small groups (Cowden and Santiago, 2016). Although, the elements are in constant interaction, students are responsible of their learning, implying that they have the main role in the cognitive process and should work actively, in group, to solve a problem. On the other hand, instructors act as coaches, they incite group discussion, and they are in charge of monitoring the process. Students are the main characters, since PBL methodology emerged from constructivist learning theories and it was developed as an alternative to conventional teaching (Loyens et al., 2006). Constructivism suggests that humans build knowledge from their experiences and, contrary to traditional education, where students receive knowledge like empty vessels to be filled, in constructivist, students are encouraged to confront what they know (Bada and Olusegun, 2015). It is evident that, long-term memorability is enhanced by PBL, because it fosters the utilization of previous knowledge to solve a new problem and demands students to put in practice what they have already been taught, therefore, facilitating the comprehension of the concepts (Schmidt et al., 2011). Other benefits that come along with PBL include the improvement of student’s creative thinking, self-regulated skills, and self-evaluation (Jansson et al., 2015; Yoon et al., 2014). Therefore, to improve chemistry student’s learning experience, the PBL approach can be used for a better comprehension of the importance of Green Chemistry. According to the U.S. Environmental Protection Agency (EPA, 1990), Green Chemistry is the design of chemical products and processes that reduce or eliminate the use or generation of hazardous substances; this designing process can be assisted by the Twelve Principles of Green Chemistry (Lancaster, 2002). The principles are qualitative, and their aim is to minimize the impact of chemical activities on human health and environment without compromising the chemical process (Ribeiro and Machado, 2013). There is a commitment to green chemistry education (Armstrong et al., 2018), and efforts have been made to implement it, at the undergraduate level (Timmer et al., 2018; Kennedy, 2016; Manchanayakage, 2013), but there is an uneven development of green chemistry curricular materials, since there have been few comprehensive reforms for general chemistry lecture or laboratory curricula (Armstrong et al., 2019). For example, Green Chemistry has not been covered extensively by chemistry A problem-based learning (PBL) methodology was implemented to a project, whose main objectives were to discuss and apply the Twelve Principles of Green Chemistry to the study of poly(vinyl alcohol)’s cross-linking reaction with dicarboxylic acids. The five participating students were oriented to be responsible for their own learning and the professor participated as an advisor. The problem was proposed and students planned all their activities to accomplish the objectives and goals, reviewed recent information in scientific literature and summarized it, made experimental work, prepared written reports, and were evaluated in seminars. The results obtained by the students were assessed through the generation of a final report and also with a final oral presentation in front of faculty members. The experience lived by the collaborative workgroup during the development and execution of the project, is described. This research is an example of how the PBL methodology can motivate the active participation of students when solving problems. The next step is to introduce this tool to teachers and students of other undergraduate courses or laboratories, since it causes a difference in the way education is being perceived in our university, because it emphasizes the application and understanding of concepts over simple memorization.

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Functionalized Polyvinyl Alcohol–Gelatin Graft for the Treatment of Tympanic Membrane Perforations

Joseph,

Ramesh,

Sayooj

et al. 2024

J Biomedical Materials Res

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The majority of issues related to patients suffering from conductive hearing loss and repeated otitis media are due to chronic tympanic membrane perforations. This generally requires a surgical procedure called tympanoplasty to seal the perforation where autologous grafts are used to reconstruct the membrane. However, the limitations associated with surgical procedures and the limited graft‐material availability often cause difficulties in this route; demanding novel procedures or materials. The basic requirements for a synthetic graft‐material for this application cover excellent cell adherence with no immune response and inflammatory actions at the site of implantation along with wound‐healing characteristics and sufficient acoustic and mechanical properties. With this aim, an innovative graft material has been developed with polyvinyl alcohol (PVA) as the base component through this work. To ensure better cell adhesion and proliferation, a natural polymer, gelatin, has been cross‐linked with PVA through a maleic anhydride (MA) intermediate; with a two‐step synthesis protocol. The mechanical strength of graft material has been found to be tunable by adjusting the ratio of gelatin with PVA. Laser Doppler Vibrometry (LDV) has been employed to evaluate its acoustic properties upon exposure to a frequency sweep of 10—8000 Hz. The in vitro biocompatibility assays using L929 and RPMI 2650 cells substantiate the material's compatibility; ensuring its potential clinical applications toward chronic tympanic membrane perforations.

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Poly(vinyl alcohol) Membranes Cross‐linked with Maleic Anhydride and 2,5‐Furandicarboxylic Acid: Conventional Heating and Microwave Irradiation

Cited by 6 publications

References 38 publications

A review on carboxylic acid cross‐linked polyvinyl alcohol: Properties and applications

A review on carboxylic acid cross‐linked polyvinyl alcohol: Properties and applications

Problem-Based Learning Approach to Review the Principles of Green Chemistry Applied to a Polycondensation Reaction

Functionalized Polyvinyl Alcohol–Gelatin Graft for the Treatment of Tympanic Membrane Perforations

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