Poly(vinylidene fluoride-trifluoroethylene)/NAY zeolite hybrid membranes as a drug release platform applied to ibuprofen release

Salazar, Hugo; Lima, Amanda Camerini; Lopes, Ana Catarina; Botelho, Gabriela; Lanceros‐Méndez, S.

doi:10.1016/j.colsurfa.2014.12.064

Cited by 37 publications

(27 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Considering the chemical structures of the three cases studied in this paper, amoxicillin [22], epicatechin [23] and triclosan; amoxicillin has a greater number of functional groups (7) has the ability to interact, and establish hydrogen bonds, with the other components of the fibers, CA and PVP. Following amoxicillin, epicatechin has 5 possible molecular interaction sites, and finally, triclosan has fewer potential interaction sites (1). These possible sites of interaction are marked in (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Different polymeric materials are used today for the release of drugs, among them are poly (vinylidene fluoridetrifluoroethylene)/NAY zeolite [1], poly (ε-caprolactone) [2], synthetic polymers [3], polymeric micelles [4], biopolymers as cellulose [5], among others. Different methods of preparing materials with drug delivery properties are reported including electrospinning, a versatile and easy method [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Preparation and Characterization of Coaxial Electrospun Fibers Containing Triclosan for Comparative Study of Release Properties with Amoxicillin and Epicatechin

Rodríguez-Félix¹,

Castillo‐Ortega

Nájera-Luna³

et al. 2016

CDD

View full text Add to dashboard Cite

The optimal conditions for the fibers preparation of cellulose acetate (CA) and poly(vinyl pyrrolidone) (PVP) containing triclosan within the fiber were successfully found; the physicochemical characteristics of these fibrous membranes were corroborated by FTIR spectroscopy, thermal analysis, mechanical tests, SEM , and TEM analysis. The formation of composite fibers of CA and PVP containing triclosan at the core of the fiber was evidenced. A comparative study of the release properties of amoxicillin, epicatechin or triclosan embedded into fibers CA/PVP/CA was performed. As more interactions of the drug with CA or PVP occur, slower release of the drug into the release medium takes place. Regarding the drug delivery system design, it is important to consider the possible molecular interactions between the material components and predict how fast or slow the drug will be delivered into the corresponding medium.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Coaxial Electrospun Fibers Containing Triclosan for Comparative Study of Release Properties with Amoxicillin and Epicatechin

Rodríguez-Félix¹,

Castillo‐Ortega

Nájera-Luna³

et al. 2016

CDD

View full text Add to dashboard Cite

show abstract

“…Carbon nanotubes (CNTs) were also investigated as potential delivery vehicles of nucleic acids, proteins and drug molecules, as well as ceramic nanotubes, including SiO 2 , TiO 2 , ZrO 2 , CeO 2 , and ZnCr 2 O 4 [10][11][12]. However, toxicity concerns and high cost make these materials less attractive for large-scale applications [13,14]. Therefore, to find novel tubular nanomaterials for drug release is urgent.…”

Section: Introductionmentioning

confidence: 99%

Functionalization of halloysite nanotubes by enlargement and hydrophobicity for sustained release of analgesic

Zhu

Zhou

et al. 2015

Colloids and Surfaces A: Physicochemical and Engineering Aspect

View full text Add to dashboard Cite

“…As the release of drugs directly embedded into membranes tends to be too fast and difficult to control, zeolites can be used to sustain the drug release for a prolonged time due to their unique characteristics such as rigid structure, high adsorption ratios, tunable hydrophobicity, and controlled pore structure . In this sense, several zeolite‐based systems have been reported for drug delivery applications, nevertheless there are just a few studies reporting their use in the form of film or membrane composites . Among the different zeolite structures, faujasite has proven to be a suitable support for drug release and has been explored for the encapsulation of drug molecules such as ibuprofen (IBU) …”

Section: Introductionmentioning

confidence: 99%

Magnetically Controlled Drug Release System through Magnetomechanical Actuation

Barbosa

Correia

Ribeiro

et al. 2016

Adv Healthcare Materials

View full text Add to dashboard Cite

A drug release system is developed capable to modulate the drug release kinetics by the application of a magnetic field. Thus, this work reports on the production, characterization, and release kinetics of a poly(l-lactic acid) (PLLA) microporous membrane containing a zeolite (Faujasite) and a magnetic stimuli-sensitive component, magnetostrictive Terfenol-D (TD), for the release of ibuprofen (IBU) as drug model. For membranes containing IBU-loaded zeolites and TD without an applied AC magnetic field, the release kinetics is characterized by a first order release. On the other hand, the application of an AC magnetic field modifies the release profile of the membrane, leading to an increase of the release rate by more than 30%, the magnetically driven release being characterized by a super case-II within the Korsmeyer-Peppas model, indicating a release mainly driven by a swelling or erosion mechanism, induced by the magnetostrictive particles under the applied magnetic field. The increase of the TD w/w from 10% to 20% has as a consequence a decrease in the quantity of IBU released from 79% to 70%; on the contrary, increasing the H intensity from 100 to 200 mT promotes an increase on the percentage of IBU released from 67% to 75%.

show abstract

Poly(vinylidene fluoride-trifluoroethylene)/NAY zeolite hybrid membranes as a drug release platform applied to ibuprofen release

Cited by 37 publications

References 37 publications

Preparation and Characterization of Coaxial Electrospun Fibers Containing Triclosan for Comparative Study of Release Properties with Amoxicillin and Epicatechin

Preparation and Characterization of Coaxial Electrospun Fibers Containing Triclosan for Comparative Study of Release Properties with Amoxicillin and Epicatechin

Functionalization of halloysite nanotubes by enlargement and hydrophobicity for sustained release of analgesic

Magnetically Controlled Drug Release System through Magnetomechanical Actuation

Contact Info

Product

Resources

About