Poly[(μ₃-rac-5-ethoxycarbonyl-6-hydroxy-6-methyl-4-phenyl-4,5,6,7-tetrahydrobenzo[c]isoxazol-3-olato)potassium]

Abstract

The title compound, [K(C17H18NO5)]n, reveals the relative configuration (4R*,5S*,6R*) whereas its crystals are racemic. The cyclo­hexane ring adopts a half-chair conformation and the isoxazole ring has an envelope conformation. The ethyl fragment of the eth­oxy­carbonyl group at position 5 is disordered in a 0.547 (7):0.453 (7) ratio. The K+ ion is surrounded by five O atoms from three ligands at distances ranging from 2.606 (2) to 3.028 (2) Å, generating a three-dimensional network. The crystal packing displays inter­molecular O—H⋯N and O—H⋯O hydrogen bonds in which the hy­droxy group acts as a double proton donor.

Syntheses and some features of five new cyclohexane-1,3-dicarboxylates with multiple stereogenic centers

“…The significant positive slopes of these correlations suggest a surprisingly strong electronic effect of the para-X group, the 1 H chemical shifts of OAH proton being more sensitive (r I = 1.42d OAH À 6.49) than NAH (r I = 1.09d NAH À 9.41) one. The obtained correlations can be used to predict and tune some properties of cyclohexanes of this type such as acidity, coordination ability [36], biological activity [5,20].…”