Polyaniline as a sacrificing template for the synthesis of controlled Co3O4 nanoparticles for the sensitive and selective detection of methotrexate (MTX)
“…Generally, an MTX value above 10 μM is very dangerous for a period of 10 hours. 6 The practical applicability of the synthesized material has been investigated by PL quenching efficiency in real samples such as artificial urine (AU) and human blood serum (HBS), as shown in Fig. 5 and 6.…”
Section: Real Sample Analysismentioning
confidence: 99%
“…This increase in the MTX level in blood results in some severe diseases, such as poisoning effects to the lungs, ulcers of the stomach, and heart stroke. 6 Considering all these issues, the development of fast and sensitive detection methodologies is required. The low safety window of MTX makes it necessary to monitor its therapeutic levels in the human body.…”
Section: Introductionmentioning
confidence: 99%
“…This increase in the MTX level in blood results in some severe diseases, such as poisoning effects to the lungs, ulcers of the stomach, and heart stroke. 6…”
In this work, we have developed a sensing platform using phosphorene-based fluorescent material Ph–Cys–Au for the detection and cytotoxicity screening of the anticancer drug methotrexate (MTX) in both aqueous media and real samples.
“…Generally, an MTX value above 10 μM is very dangerous for a period of 10 hours. 6 The practical applicability of the synthesized material has been investigated by PL quenching efficiency in real samples such as artificial urine (AU) and human blood serum (HBS), as shown in Fig. 5 and 6.…”
Section: Real Sample Analysismentioning
confidence: 99%
“…This increase in the MTX level in blood results in some severe diseases, such as poisoning effects to the lungs, ulcers of the stomach, and heart stroke. 6 Considering all these issues, the development of fast and sensitive detection methodologies is required. The low safety window of MTX makes it necessary to monitor its therapeutic levels in the human body.…”
Section: Introductionmentioning
confidence: 99%
“…This increase in the MTX level in blood results in some severe diseases, such as poisoning effects to the lungs, ulcers of the stomach, and heart stroke. 6…”
In this work, we have developed a sensing platform using phosphorene-based fluorescent material Ph–Cys–Au for the detection and cytotoxicity screening of the anticancer drug methotrexate (MTX) in both aqueous media and real samples.
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