“…However, the direct electron transfer for oxidation of FADH 2 or reduction of FAD (Shan, Yang, Song, Han, Ivaska, & Niu, 2009) is hard to realize at conventional electrodes, because the FAD is deeply seated in a cavity and not easily accessible for conduction of electrons from the electrode surface. Thus, many CNTsbased nanohybrids, such as MWCNT/AuNPs/ionic liquid (F. Jia, Shan, Li, & Niu, 2008), SWCNT/GOD/Nafion (Lyons & Keeley, 2008), polyaniline (PANI)-coated Fe 3 O 4 nanoparticle/MWCNT (Zhun Liu, Wang, Xie, & Chen, 2008), and palladium/SWCNT (Meng, Jin, Yang, Lu, Zhang, & Cai, 2009), have been explored to immobilize GOD for glucose biosensing. More interestingly, Willner's group demonstrated that aligned reconstituted GOD on the edge of SWCNT as conductive nanoneedles can be linked to an electrode surface for fast glucose response (G. Liu & Lin, 2006).…”