“…Different compounds can be used to produce antibacterial functionalization of HA including antibacterial polymers, nanoparticles, antibiotics, and proteins. Among them, antibacterial polymers, such as chitosan, and polycaprolactone (PCL), are frequently preferred for the obtention of HA composites with antibacterial properties [87,90,91,[98][99][100][101][102]. Metallic nanoparticles, such as silver, zinc dioxide, titanium dioxide, and niobium pentoxide, have been combined with graphene and hydroxyapatite to produce composites with antibacterial properties [64,80,94,[103][104][105].…”