Polycystic ovary syndrome: it is always bilateral?

Battaglia, Cesare; Regnani, Giorgia; Primavera, M.R.; Salvatori, M.; Volpe, Annibale

doi:10.1046/j.1469-0705.1999.14030183.x

Cited by 14 publications

(8 citation statements)

References 49 publications

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“…In 1999, in an observational study of 16 women with unilateral PCO and 20 women with bilateral PCO, Battaglia and co-workers [42] reported that the women in the latter group had higher concentrations of androstenedione and LH to FSH ratios. Furthermore, in women with unilateral PCO, grey scale and Doppler ultrasound showed different features in the affected and the unaffected ovary, similar to the appearance of the polycystic and the normal ovary, respectively [42]. …”

Section: The Unilateral Polycystic Ovarymentioning

confidence: 99%

Polycystic ovaries

Lakhani¹,

Seifalian²,

Atiomo³

et al. 2002

BJR

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Transvaginal ultrasound is currently the gold standard for diagnosing polycystic ovaries. The results of studies using ultrasound suggest a prevalence in young women of at least 20%. Between 5% and 10% of these women with polycystic ovaries shown on ultrasound will have the classical symptoms of polycystic ovary syndrome such as infertility, amenorrhoea or signs of hirsutism and obesity, as originally described by Stein and Leventhal in 1935. However, the significance of polycystic ovaries in asymptomatic women is still under investigation, as is the role of Doppler (pulsed and colour) and three-dimensional ultrasound. Ultrasound has also contributed to our understanding of the local and systemic haemodynamic changes associated with polycystic ovaries, although the relationship of these changes to morbidity and mortality is unknown.

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Section: The Unilateral Polycystic Ovarymentioning

confidence: 99%

Polycystic ovaries

Lakhani¹,

Seifalian²,

Atiomo³

et al. 2002

BJR

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“…No difference was seen in LH, FSH, estradiol, or testosterone levels 14 not only were serum LH and testosterone significantly higher in the bilateral group but LH as well as insulin levels in follicular fluid were also significantly higher in women with bilateral polycystic ovaries. In an observational study in adults, Battaglia et al found that women with bilateral PCOS had significantly higher androstenedione and LH/FSH ratio than matched women with unilateral PCOS.…”

Section: Discussionmentioning

confidence: 67%

Unilateral Ovarian Enlargement in Adolescents with Polycystic Ovary Syndrome: A Variant of Bilateral Disease

Shah

Golden²,

Milla³

2010

Journal of Pediatric Endocrinology and Metabolism

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Aims: To evaluate clinical, biochemical and radiological features in adolescent females •with unilateral polycystic ovary (UniPCO) versus bilateral polycystic ovary (BiPCO) in patients with polycystic ovarian syndrome (PCOS), and to compare the association of insulin resistance (IR) and metabolic syndrome (MS) between the two groups. Setting: Pediatric endocrine clinic. Methods: A retrospective chart review of girls with the diagnosis of PCOS was performed. They were divided into two groups: PCOS with UniPCO and BiPCO. Results: No difference was seen between the two groups in regard to clinical parameters. LH/FSH ratio was significantly higher in patients with BiPCO. No difference was seen in free testosterone, lipids, MS or IR between groups. Ultrasound showed a mean ovarian volume, of 13.2 ± 1.5 ml on the affected side in UniPCO and 16.1 ± 1.2 ml in BiPCO. Ovarian follicle location was mostly peripheral in both UniPCO and BiPCO. Multiple follicles were found in the majority of cases. IR and MS were present in 40% of girls with UniPCO and 38% and 23%, respectively, in girls with BiPCO. Conclusion: UniPCO may be a forerunner of BiPCO and may represent an early point along the continuum. Later, the unaffected ovary continues to increase in volume, resulting in BiPCO. Metabolic abnormalities of patients

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“…3). The authors speculated that in unilateral or in partial PCOS the peripheral expression of ovarian receptors for LH or environmental factors (surgery, infections, ovarian vascularization) may limit the morphological and functional features of PCOS to a single ovary or to a specific portion of the ovaries [61,62].…”

Section: Identification Of Polycystic Ovaries On Pelvic Ultrasoundmentioning

confidence: 99%

The Ultrasonographic Diagnosis of Polycystic Ovary Syndrome

Battaglia

Persico

Mancini

et al. 2006

CMIR

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Polycystic ovary syndrome (PCOS) is one of the most controversial endocrine disease, for its clinical and biochemical heterogeneity. Many authors focused on the possible role of genetic, environmental and hormonal factors in the development of the syndrome, but the etiopathogenesis still remains unclear.The diagnostic criteria for the definition of PCOS are as heterogeneous as the disease itself and underwent more than one revision throughout the last years.Ultrasonography has been widely accepted as an important criterion for the detection of polycystic ovaries. Furthermore, Doppler flow analysis of both intraovarian and uterine arteries seems to provide an insight to the pathological state and the degree of progression of the disease. In this review, we provide the state of the art for a correct diagnosis of PCOS, pointing out the capacity of ultrasonography and color Doppler imaging in the early detection of the syndrome and the possibility to obtain additional information about its pathophysiology. Since PCOS patients have higher cardiovascular risk the precocity and the precision of the diagnosis is extremely important to improve the long-term prognosis.

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Polycystic ovary syndrome: it is always bilateral?

Abstract: Polycystic ovary syndrome does not predetermine a single ultrasonographic and Doppler pattern.

Cited by 14 publications

References 49 publications

Polycystic ovaries

Polycystic ovaries

Unilateral Ovarian Enlargement in Adolescents with Polycystic Ovary Syndrome: A Variant of Bilateral Disease

The Ultrasonographic Diagnosis of Polycystic Ovary Syndrome

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