Polycystic ovary syndrome

Maharaj, Sureka; Amod, Aslam

doi:10.1080/22201009.2009.10872199

Cited by 12 publications

(8 citation statements)

References 106 publications

(104 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Disagreement has persisted regarding whether the two additional phenotypes (oligo-ovulation with PCO or hyperandrogenism with PCOS) in Rotterdam criteria actually do have classical PCOS, because PCO on ultrasound is a very common finding in normal population [20]. Also in some studies they found that using NIH criteria predicts the metabolic risk more appropriately than Rotterdam criteria [21].…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of polycystic ovary syndrome: a cross sectional study of university students at An-Najah national university-Palestine

Musmar

Afaneh

Mo'alla

2013

Reprod Biol Endocrinol

View full text Add to dashboard Cite

BackgroundPolycystic Ovary Syndrome (PCOS) is the most common gynecological endocrinopathy in women of reproductive age. Despite its heavy burden on female reproduction and general health, there is no study regarding PCOS prevalence in Palestine. This study aims to establish prevalence of PCOS among female university students at An-Najah National University-Palestine and to explore its possible risk factors.MethodsA cross sectional study was conducted on 137 female students using convenience sampling method for age group (18–24) years. PCOS cases were identified according to the National Institute of health (NIH) criteria through clinical interview and assessment for participants at the University clinics. Menstrual irregularities regarding cycle and flow were identified and clinical hyperandrogenism was assessed as the self-reported degree of hirsutism using the modified Ferriman Gallwey (mF-G) scoring method of more than 8 score. Biochemical hyperandrogenism for girls with menstrual irregularities was assessed by measuring free testosterone level. Data were analyzed using SPSS version 17 applying descriptive methods; different risk factor relationships were estimated using bivariate analysis and multivariate logistic regression.ResultsThe estimated prevalence of PCOS was 7.3% , acne was the only studied risk factor among others to be statistically significantly related to PCOS patients (OR = 8.430, P-value = 0.015). Clinical Hirsutism was found in 27% of participants, 70% of whom had idiopathic hirsutism.ConclusionsPrevalence of PCOS in Palestine seems to be relatively high but similar to other Mediterranean statistics. We recommend further studies using wider age group and larger sample for all parts of Palestine in order to generalize results.

show abstract

Section: Discussionmentioning

confidence: 99%

Epidemiology of polycystic ovary syndrome: a cross sectional study of university students at An-Najah national university-Palestine

Musmar

Afaneh

Mo'alla

2013

Reprod Biol Endocrinol

View full text Add to dashboard Cite

show abstract

“…Androgens, including testosterone, are present in both sexes, however, the levels are generally lower in females than males. A prominent feature of PCOS is elevated concentrations of testosterone, which account for numerous of the PCOS related symptoms, including hirsutism, acne, scalp hair loss, irregular menses, and diminished fertility 9,11,62. Hyperandrogenism is implicated in PCOS9 and binge eating behavior63,64 and has frequently been linked to the causation of menstrual irregularities, including amenorrhea, and a delay and/or lack of ovulation 65,66.…”

Section: What Are the Connections Between Pcos And Binge Eating Behavmentioning

confidence: 99%

“…Insulin resistance is a strong risk factor for metabolic syndrome, a cluster of biochemical and physiological abnormalities associated with the development of cardiovascular disease and type 2 diabetes, which is commonly found in women with PCOS 12. Excess weight and inactivity independently increase the severity of insulin resistance,10,62,72 and women with PCOS report excess weight as a major source of concern and stress 73. 72,74…”

Section: What Are the Connections Between Pcos And Binge Eating Behavmentioning

confidence: 99%

See 1 more Smart Citation

<p>Binge eating in patients with polycystic ovary syndrome: prevalence, causes, and management strategies</p>

Krug¹,

Giles²,

Paganini³

2019

NDT

View full text Add to dashboard Cite

Emerging evidence suggests that disordered eating, particularly binge-eating symptomatology, is overrepresented within Polycystic Ovary Syndrome (PCOS) populations. This comorbidity presents a clinical dilemma as current treatment approaches for PCOS emphasize the importance of weight management, diet, exercise, and the potential for harm of such treatment approaches in PCOS patients with comorbid disordered eating. However, limited research has assessed the occurrence of binge eating and disordered eating in PCOS patients. Consequently, little is known about the prevalence of binge eating in PCOS, and the possible etiological processes to explain this comorbidity remain poorly understood. Given the paucity of research on this topic, the aims of this narrative review are fourfold: 1) to outline the main symptoms of PCOS and binge eating; 2) to provide an overview of the prevalence of binge eating in PCOS; 3) to outline possible etiological factors for the comorbidity between PCOS and binge eating; and 4) to provide an overview of management strategies of binge eating in PCOS.

show abstract

“…It showed that increasing oxidative stress in the ovaries of rats with PCOS causes ovary epithelium DNA damage and granulosic cell apoptosis by increased oxidative stress caused by ROS (17), which is consistent with the results of present study. Women with PCOS have metabolic abnormalities in controlling the production of androgens (18). The high concentrations of androgenic hormones such as testosterone, androstenedione, and dehydroepiandrosterone sulfate have been observed in these patients (19).…”

Section: Discussionmentioning

confidence: 99%

The Effect of Swimming Training on Serum Levels of Sex Hormones, Antioxidant Enzymes and Oxidative Damage of DNA Ovarian Tissue in Rats with Polycyclic Ovarian Syndrome

Noura

Rafie²,

Hosseini

et al. 2020

Ann Appl Sport Sci

View full text Add to dashboard Cite

Background. Hormone disorders, stress-oxidative and inflammation in ovarian tissue cause no-ovulation in women with polycyclic ovarian syndrome (PCOS). Several studies have shown the role of exercises in control of sex hormones. Objectives. The aim of this study was to investigate the effect of 6 weeks of swimming training (ST) on serum levels of sex hormones, antioxidant enzymes and oxidative damage of DNA ovarian tissue in rats with PCOS. Methods. In this experimental study, 30 female Wistar rats were divided into 3 groups included control, PCO (letrozole consumption for 28 days intra-peritoneally) and PCO+ST groups. PCOS was induced with 28 days of peritoneal injection of 1 mg/kg letrozole. The ST program was included 6 weeks of ST for 20 minutes per day. At the end of the treatment period, serum levels of LH, FSH, testosterone, estradiol and progesterone, SOD, CAT, GPX, MDA and HOdG-8 in ovarian tissue were measured by ELISA method. Results. ST significantly decreased serum levels of LH, estradiol, testosterone, MDA and HOdG-8 levels (p<0.05) as well as increased SOD, CAT, and GPX enzymes of rats with PCOS (p<0.05). Conclusion. It appears that ST has antioxidant and sex hormone enhancing effects in ovarian tissue of rats with PCOS model.

show abstract

Polycystic ovary syndrome

Cited by 12 publications

References 106 publications

Epidemiology of polycystic ovary syndrome: a cross sectional study of university students at An-Najah national university-Palestine

Epidemiology of polycystic ovary syndrome: a cross sectional study of university students at An-Najah national university-Palestine

<p>Binge eating in patients with polycystic ovary syndrome: prevalence, causes, and management strategies</p>

The Effect of Swimming Training on Serum Levels of Sex Hormones, Antioxidant Enzymes and Oxidative Damage of DNA Ovarian Tissue in Rats with Polycyclic Ovarian Syndrome

Contact Info

Product

Resources

About