Polycythemia of stress in psychiatric hospital populations

Benitone, Jerry; Kling, Arthur

doi:10.1016/0022-3999(70)90075-9

Cited by 11 publications

(1 citation statement)

References 7 publications

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“…Adrenaline and noradrenaline infusions have been noted to lead to an increase in venous tone with mild reductions in PV and small increases in PCV (38,39), and in occasional patients with phaeochromocytoma raised PCV may be found in association with reduced PV (40,41). While mental and physical stress does stimulate the autonomic nervous system and increases catecholamine levels, the evidence for an association with polycythaemia is tenuous (42)(43)(44)(45)(46).…”

Section: Stressmentioning

confidence: 99%

Apparent polycythaemia: diagnosis, pathogenesis and management

Messinezy

Pearson

1993

European J of Haematology

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The term “apparent polycythaemia” is applied to a group of patients who have a raised PCV (<0.51 in males, <0.48 in females) but a normal red cell mass (less than 25% above their predicted mean normal value). Some have additionally a marked reduction in plasma volume and can be defined as a subgroup: relative polycythaemia. Smoking, hypertension and to a lesser extent obesity, excessive alcohol, low‐dose diuretic therapy and hypoxaemia have all been associated with apparent polycythaemia but the mechanism is both uncertain and likely to be complex. This group of patients is unlikely to be uniform in pathogenesis and may well include some normal individuals. Investigation requires exclusion of factors associated with other types of polycythaemia. The possibility of an increased vascular occlusive risk is uncertain in these patients except at the higher PCV values. Reduction of PCV by venesection is sensible at PCV < 0.54 or where there is perceived to be an increased risk of vascular occlusion. The remaining patients should be managed by regular observation to detect further rise in PCV or evolution to absolute polycythaemia (raised red cell mass). In some, the PCV returns to normal.

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