Polydopamine and Its Derivative Surface Chemistry in Material Science: A Focused Review for Studies at KAIST

Lee, Haesung A.; Park, Eunsook; Lee, Haeshin

doi:10.1002/adma.201907505

Cited by 246 publications

(191 citation statements)

References 111 publications

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“…The same author also showed that mechanical properties of PDA coating can be further enhanced, and the roughness reduced, by treatment with blue-diode laser treatment, inducing graphitization while preserving multifunctionality [90]. Surface adhesion of PDA and related materials have been investigated in detail also by Lee and coworkers [91], who demonstrated that the stability of the obtained coatings is widely independent on the chemical composition of the surface itself [92]. This feature is surely advantageous since it allows a very general approach to surface functionalization.…”

Section: Functionalization and Coating: Use As A Bio-template Or As Amentioning

confidence: 94%

Bio-Applications of Multifunctional Melanin Nanoparticles: From Nanomedicine to Nanocosmetics

et al. 2020

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Bioinspired nanomaterials are ideal components for nanomedicine, by virtue of their expected biocompatibility or even complete lack of toxicity. Natural and artificial melanin-based nanoparticles (MNP), including polydopamine nanoparticles (PDA NP), excel for their extraordinary combination of additional optical, electronic, chemical, photophysical, and photochemical properties. Thanks to these features, melanin plays an important multifunctional role in the design of new platforms for nanomedicine where this material works not only as a mechanical support or scaffold, but as an active component for imaging, even multimodal, and simple or synergistic therapy. The number of examples of bio-applications of MNP increased dramatically in the last decade. Here, we review the most recent ones, focusing on the multiplicity of functions that melanin performs in theranostics platforms with increasing complexity. For the sake of clarity, we start analyzing briefly the main properties of melanin and its derivative as well as main natural sources and synthetic methods, moving to imaging application from mono-modal (fluorescence, photoacoustic, and magnetic resonance) to multi-modal, and then to mono-therapy (drug delivery, anti-oxidant, photothermal, and photodynamic), and finally to theranostics and synergistic therapies, including gene- and immuno- in combination to photothermal and photodynamic. Nanomedicine aims not only at the treatment of diseases, but also to their prevention, and melanin in nature performs a protective action, in the form of nanopigment, against UV-Vis radiations and oxidants. With these functions being at the border between nanomedicine and cosmetics nanotechnology, recently examples of applications of artificial MNP in cosmetics are increasing, paving the road to the birth of the new science of nanocosmetics. In the last part of this review, we summarize and discuss these important recent results that establish evidence of the interconnection between nanomedicine and cosmetics nanotechnology.

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Section: Functionalization and Coating: Use As A Bio-template Or As Amentioning

confidence: 94%

Bio-Applications of Multifunctional Melanin Nanoparticles: From Nanomedicine to Nanocosmetics

et al. 2020

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“…In vivo, melanin is produced from 3,4-dihydroxyphenylalanine (DOPA), an amino acid, and is classified into pheomelanin, eumelanin and neuromelanin depending on the composition ( Figure 3) [30,31]. [42][43][44][45][46][47].…”

Section: Characteristics Of Polydopamine As a Melanin Mimetic Materialsmentioning

confidence: 99%

Progress in polydopamine-based melanin mimetic materials for structural color generation

Kohri

2020

Science and Technology of Advanced Materials

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Structural color is a color derived from optical interaction between light and a microstructure and is often seen in nature. Natural melanin plays an important role in bright structural coloration. For example, the vivid colors of peacock feathers are due to structural colors. The periodic arrangement of melanin granules inside the feathers leads to light interference, and the black granules absorb scattered light well, resulting in bright structural color. In recent years, polydopamine (PDA) has attracted attention as a melanin mimetic material. This review article summarizes recent research on structural coloration using PDAbased artificial melanin materials. It also outlines possible applications using bright structural colors realized by artificial melanin materials and future perspectives.

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“…Dopamine, a catecholamine neurotransmitter, has emerged in the last decade as a versatile building block for countless biotechnological and biomedical applications [ 1 , 2 , 3 ]. As first reported by Messersmith and coworkers [ 4 ], oxidative self-polymerization of dopamine in an aqueous alkaline solution [ 5 ] can be used to yield polydopamine film, a robust universal coating material.…”

Section: Introductionmentioning

confidence: 99%

“…As first reported by Messersmith and coworkers [ 4 ], oxidative self-polymerization of dopamine in an aqueous alkaline solution [ 5 ] can be used to yield polydopamine film, a robust universal coating material. The low cost of dopamine and the simplicity of polydopamine deposition on virtually any object, advanced polydopamine research and usage, though the exact self-polymerization mechanism as well as polydopamine structure are still in debate [ 1 , 2 , 3 ]. Nevertheless, studies on polydopamine films deposited onto surfaces under various conditions, revealed the importance of factors such as solution pH, dopamine concentration and self-polymerization time in controlling film thickness [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Dopamine Self-Polymerization as a Simple and Powerful Tool to Modulate the Viscoelastic Mechanical Properties of Peptide-Based Gels

Fichman

2021

Molecules

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Dopamine is a small versatile molecule used for various biotechnological and biomedical applications. This neurotransmitter, in addition to its biological role, can undergo oxidative self-polymerization to yield polydopamine, a robust universal coating material. Herein, we harness dopamine self-polymerization to modulate the viscoelastic mechanical properties of peptide-based gels, expanding their ever-growing application potential. By combining rapid peptide assembly with slower dopamine auto-polymerization, a double network gel is formed, where the fibrillar peptide gel network serves as a scaffold for polydopamine deposition, allowing polydopamine to interpenetrate the gel network as well as establishing crosslinks within the matrix. We have shown that triggering the assembly of a lysine-rich peptide gelator in the presence of dopamine can increase the mechanical rigidity of the resultant gel by a factor of 90 in some cases, while retaining the gel’s shear thin-recovery behavior. We further investigate how factors such as polymerization time, dopamine concentration and peptide concentration alter the mechanical properties of the resultant gel. The hybrid peptide–dopamine gel systems were characterized using rheological measurements, circular dichroism spectroscopy and transmission electron microscopy. Overall, triggering peptide gelation in the presence of dopamine represents a simple yet powerful approach to modulate the viscoelastic mechanical properties of peptide-based gels.

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Polydopamine and Its Derivative Surface Chemistry in Material Science: A Focused Review for Studies at KAIST

Cited by 246 publications

References 111 publications

Bio-Applications of Multifunctional Melanin Nanoparticles: From Nanomedicine to Nanocosmetics

Bio-Applications of Multifunctional Melanin Nanoparticles: From Nanomedicine to Nanocosmetics

Progress in polydopamine-based melanin mimetic materials for structural color generation

Dopamine Self-Polymerization as a Simple and Powerful Tool to Modulate the Viscoelastic Mechanical Properties of Peptide-Based Gels

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