Polydopamine-mediated bio-inspired synthesis of copper sulfide nanoparticles for T1-weighted magnetic resonance imaging guided photothermal cancer therapy

Xiong, Yuxuan; Sun, Fei; Zhang, Yifan; Yang, Zhe; Liu, Pei; Zou, Yibiao; Yu, Yiming; Tong, Fan; Yi, Changfeng; Yang, Shengli; Xu, Zushun

doi:10.1016/j.colsurfb.2018.10.023

Cited by 32 publications

(12 citation statements)

References 58 publications

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“…For the PDA@FeS NPs, the zeta potential showed high negative surface charges, which endowed the PDA@FeS NPs with colloidal nature, thereby improving the dispersity and stability in aqueous solution. 28 The FT-IR spectrum was carried out and the result was shown in Fig. 2a.…”

Section: Papermentioning

confidence: 99%

A bioinspired polydopamine–FeS nanocomposite with high antimicrobial efficiency via NIR-mediated Fenton reaction

Huang

Shi

et al. 2023

Dalton Trans.

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Section: Papermentioning

confidence: 99%

A bioinspired polydopamine–FeS nanocomposite with high antimicrobial efficiency via NIR-mediated Fenton reaction

Huang

Shi

et al. 2023

Dalton Trans.

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“…Despite this preparative complication it was substantiated that the tailor-made NP could be successfully employed for combined imaging-guided PTT. In similar fashion, PDA was used as a bio-template for the synthesis of a copper sulfide nano-PTA followed by further chelation of iron ions [163]. The resulting so-called CuPDF NP were reported to be ideal for MRI guided photothermal cancer therapy as they showed an enhanced photothermal efficacy, compared to pure PDA nanoparticles, together with an evident MRI signal enrichment.…”

Section: Photothermal Therapy (Ptt)mentioning

confidence: 99%

Bio-Applications of Multifunctional Melanin Nanoparticles: From Nanomedicine to Nanocosmetics

et al. 2020

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Bioinspired nanomaterials are ideal components for nanomedicine, by virtue of their expected biocompatibility or even complete lack of toxicity. Natural and artificial melanin-based nanoparticles (MNP), including polydopamine nanoparticles (PDA NP), excel for their extraordinary combination of additional optical, electronic, chemical, photophysical, and photochemical properties. Thanks to these features, melanin plays an important multifunctional role in the design of new platforms for nanomedicine where this material works not only as a mechanical support or scaffold, but as an active component for imaging, even multimodal, and simple or synergistic therapy. The number of examples of bio-applications of MNP increased dramatically in the last decade. Here, we review the most recent ones, focusing on the multiplicity of functions that melanin performs in theranostics platforms with increasing complexity. For the sake of clarity, we start analyzing briefly the main properties of melanin and its derivative as well as main natural sources and synthetic methods, moving to imaging application from mono-modal (fluorescence, photoacoustic, and magnetic resonance) to multi-modal, and then to mono-therapy (drug delivery, anti-oxidant, photothermal, and photodynamic), and finally to theranostics and synergistic therapies, including gene- and immuno- in combination to photothermal and photodynamic. Nanomedicine aims not only at the treatment of diseases, but also to their prevention, and melanin in nature performs a protective action, in the form of nanopigment, against UV-Vis radiations and oxidants. With these functions being at the border between nanomedicine and cosmetics nanotechnology, recently examples of applications of artificial MNP in cosmetics are increasing, paving the road to the birth of the new science of nanocosmetics. In the last part of this review, we summarize and discuss these important recent results that establish evidence of the interconnection between nanomedicine and cosmetics nanotechnology.

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“…Furthermore, the PTT effect in the Cu-BTC@PDA NWs with NIR irradiation led to concentration-dependent cell death. The cell viability decreased to 42% when the concentration of the NWs dispersions reached a high concentration (100 µg mL −1 ), suggesting that the heat produced by the NIR laser could efficiently destroy cancer cells [ 53 ]. These data clearly showed that Cu-BTC@PDA NWs were more efficient as a photothermal agent in the in vitro photothermal ablation of cancer cells.…”

Section: Discussionmentioning

confidence: 99%

Polydopamine-Coated Cu-BTC Nanowires for Effective Magnetic Resonance Imaging and Photothermal Therapy

et al. 2023

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Herein, we present a one-pot hydrothermal approach for synthesizing metal–organic framework-derived copper (II) benzene-1,3,5-tricarboxylate (Cu-BTC) nanowires (NWs) using dopamine as the reducing agent and precursor for a polydopamine (PDA) surface coating formation. In addition, PDA can act as a PTT agent and enhance NIR absorption, producing photothermal effects on cancer cells. These NWs displayed a photothermal conversion efficiency of 13.32% after PDA coating and exhibited good photothermal stability. Moreover, NWs with a suitable T1 relaxivity coefficient (r1 = 3.01 mg−1 s−1) can be effectively used as magnetic resonance imaging (MRI) contrast agents. By increasing concentrations, cellular uptake studies showed a greater uptake of Cu-BTC@PDA NWs into cancer cells. Further, in vitro studies showed PDA-coated Cu-BTC NWs possess exceptional therapeutic performance by 808 nm laser irradiation, destroying 58% of cancer cells compared with the absence of laser irradiation. This promising performance is anticipated to advance the research and implementation of copper-based NWs as theranostic agents for cancer treatment.

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Polydopamine-mediated bio-inspired synthesis of copper sulfide nanoparticles for T1-weighted magnetic resonance imaging guided photothermal cancer therapy

Cited by 32 publications

References 58 publications

A bioinspired polydopamine–FeS nanocomposite with high antimicrobial efficiency via NIR-mediated Fenton reaction

A bioinspired polydopamine–FeS nanocomposite with high antimicrobial efficiency via NIR-mediated Fenton reaction

Bio-Applications of Multifunctional Melanin Nanoparticles: From Nanomedicine to Nanocosmetics

Polydopamine-Coated Cu-BTC Nanowires for Effective Magnetic Resonance Imaging and Photothermal Therapy

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