Polyethylene wear particle generation in vivo in an alumina medial pivot total knee prosthesis

Wear Debris Characterization and Corresponding Biological Response: Artificial Hip and Knee Joints

“…The common parameters in defining each particle employed by most of the researchers were ECD, roundness (R), form factor (FF), aspect ratio (AR), and elongation factor (E) [92,99,101,112,115,127]. Most of the studies used 2D SEMs and TEMs as the input to obtain quantitative statistics.…”

In Vivo Analysis of Polyethylene Wear Particles After Total Knee Arthroplasty: The Influence of Improved Materials and Designs

“…Polyethylene wear particles were isolated and quantified with use of a previously validated technique [6][7][8][9] in which a modification of the method of Campbell et al 13 was used. All reagent solutions were filtered through a 0.2-mm-pore nylon filter (cat.…”

“…It is difficult to determine the in vivo polyethylene wear of total joint prostheses (with the exception of total hips) with use of postoperative radiographs. To measure polyethylene wear in vivo, we developed and employed a method in which we isolated and analyzed polyethylene wear particles in the synovial fluid of knees that had a well-functioning total knee prosthesis [6][7][8][9] .…”

Intervertebral disc joint replacement technology

“…However, in general the wear of metal-onmetal cobalt alloy prostheses is well below that of metal-on-polymer as has been well established in the hip arthroplasty arena (Fig. 16.10) (Callaghan et al, 2007;Catelas et al, 2004;Heisel et al, 2004;Kurtz et al, 2005;Minoda et al, 2005;Saikko et al 2002;Tipper et al, 2002;Wroblewski et al, 1996).…”

“…However, this difference is not apparent with metal-on-metal articulating implants. Figure references: metal-polymer: Callaghan et al (2007); ceramic-polymer: Minoda et al (2005); metal-x-linked polymer: Kurtz et al (2005); metal-x-linked polymer: Heisel et al (2004); metal-x-linked polymer: Wroblewski et al (1996); metal-xlinked polymer: Saikko et al (2002); ceramic-ceramic: Tipper et al (2002); metal-metal TDA: Kretzer et al (2009);Pare et al (2007b); Vicars et al (2010). living, wear particles were produced at a rate of 1.2 mg per million cycles (particle size 3.9 mm diameter, number based analysis). This resulted in a device height decrease of 0.02 mm per million cycles, where approximately 77% of this decrease was postulated to be due to gradual creep of the nucleus under the constant compressive load (anderson et al, 2003).…”