Polyethyleneimine-Oleic Acid Micelles-Stabilized Palladium Nanoparticles as Highly Efficient Catalyst to Treat Pollutants with Enhanced Performance

Lai, Xin; Zhang, Xuan; Li, Shukai; Zhang, Jie; Lin, Weifeng; Wang, Longgang

doi:10.3390/polym13111890

Cited by 3 publications

(3 citation statements)

References 37 publications

(36 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Monoclonal antibodies that recognize tumor-associated antigens are perhaps the most extensively explored ligands for targeted drug delivery [57]. The exquisite specificity of antibodies makes them well suited for directing nanoparticles to cancer cells that are overexpressing cognate receptors [58].…”

Section: Targeting Ligandsmentioning

confidence: 99%

Surface Modification of Metallic Nanoparticles for Targeting Drugs

Abdelkawi,

Slim,

Zinoune

et al. 2023

Coatings

View full text Add to dashboard Cite

This review focuses on the surface modification of metallic nanoparticles for targeted drug delivery. Metallic nanoparticles, owing to their unique size, stability, and payload capacity, have emerged as promising drug carriers. However, their application necessitates surface modification to enable precise targeting. Various strategies, such as polymer coating methods, the use of functional groups, and bio-conjugation with targeting ligands, are explored. The review also discusses the selection of ligands based on target receptors, active and passive targeting approaches, and stimuli-responsive targeting. It further delves into the challenges of translating these strategies to clinical settings, including scalability, toxicity, and regulatory hurdles. The surface modification of metallic nanoparticles is a promising avenue for targeted drug delivery. Various strategies, including polymer coating, functionalization with specific groups, and bioconjugation with targeting ligands, have been explored to enhance the therapeutic potential of these nanoparticles. The challenges in clinical translation, continuous advancements in nanoparticle synthesis, and surface modification techniques offer a positive outlook for the future of targeted metallic nanoparticle systems. Despite the promising potential of metallic nanoparticles in drug delivery, there are several challenges that need to be addressed for their successful clinical translation. These include scalable fabrication and functionalization of nanoparticles, toxicity concerns, and regulatory hurdles. However, continuous advancements in nanoparticle synthesis and surface modification techniques are expected to overcome these challenges in the near future.

show abstract

Section: Targeting Ligandsmentioning

confidence: 99%

Surface Modification of Metallic Nanoparticles for Targeting Drugs

Abdelkawi,

Slim,

Zinoune

et al. 2023

Coatings

View full text Add to dashboard Cite

show abstract

“…PEI is a hydrophilic polymer analogue of PEG, with nitrogen atoms instead of oxygen, and its copolymers have been exploited for including metal ion absorption, in vivo imaging, targeted delivery of drugs, antibacterial, antifouling, and gene-transfection . Although a number of amphiphilic PEI-dominant copolymers are reported which contain hydrophobic segments, such as alkyl groups, poly(ε-caprolactone) (PCL), tocopherol hydrogen succinate (TOS), oleic acid, and stearic acid, none of these are known to form thermogels in water. Replacement of PEG with PEI as the hydrophilic segment in thermogelling polymers can bring about several unique properties: on top of allowing convenient postsynthetic functionalization using well-established amine chemistry, the basic nitrogen atoms, with their propensity for protonation, also offer opportunities for pH-responsiveness.…”

Section: Introductionmentioning

confidence: 99%

PEG-free pH-Responsive Thermogels Containing Amphiphilic Polycationic Polyethylenimine Copolymers

Lin,

Lim,

Owh

et al. 2023

Macromolecules

View full text Add to dashboard Cite

“…In this study, amphiphilic polyethyleneimine (PEI)-oleic acid micelles-stabilized palladium nanoparticles were synthesized by Wang et al, which effectively catalyzed the reduction of 4-NP to form 4-AP and had high catalytic efficiency against morin. The authors concluded that these nanoparticles have great potential applications in treating various organic contaminants in solution in the future [ 14 ].…”

mentioning

confidence: 99%