Polymer-free drug-eluting stent in unselected patient population: A single center experience

Clinical outcomes with reservoir‐based polymer‐free amphilimus‐eluting stents in real‐world patients according to diabetes mellitus and complexity: The INVESTIG8 registry

“…The Cre8 AES is a new generation DES that has shown a favorable safety and efficacy profile in preclinical and clinical studies , with comparable outcomes between diabetic and nondiabetic patients . Importantly, the RESERVOIR RCT has recently reported the noninferiority Cre8 AES in comparison with the benchmark of durable polymer‐based EES in DM patients.…”

Five-year clinical outcome of multicenter randomized trial comparing amphilimus - with paclitaxel-eluting stents in de novo native coronary artery lesions

“…7 These promising results have been recently confirmed in the Reservoir-Based Polymer-Free Amphilimus-Eluting Stent Versus Polymer-Based Everolimus-Eluting Stent in Diabetic Patients (RESERVOIR) trial and in real-world multicentric registries. [8][9][10][11][12] However, long-term data investigating clinical outcome of this new generation DES are still not available, leaving uncertainty about the durability of the impressive mid-term efficacy and safety profile showed by the Cre8 AES. We sought to initially address these questions based on the 5-year results of the NEXT randomized trial.…”