Polymer‐Supported Sulfonic Acid‐Catalyzed Candid Synthesis and Photophysical Properties of 2H‐indazolo[2,1‐b]phthalazinetriones

Abstract

in Wiley Online Library (wileyonlinelibrary.com).Polystyrene-supported sulfonic acid has been found to be an efficient catalyst for the one-pot, three-component synthesis of 2H-indazolo[2,1-b]phthalazinetriones in greener solvent glycerol. Use of greener solvent glycerol along with a polymer-supported, low toxic, and inexpensive catalyst renders the method eco-friendly. High yields, simple product isolation procedure, and fluorescent and electroluminescent natures of the products are the noteworthy aspects of this protocol.

5-Sulphosalicylic acid: An expeditious organocatalyst for one-pot synthesis of 2H-indazolo[2,1-b]phthalazine-triones

“…Owing to such unique biological profile of phthalazine derivatives, a considerable amount of research has been paid for the synthesis of their structurally resembled drug like heterocyclic scaffolds. Therefore, number of protocols including varieties of catalysts has been developed for the synthesis of 2H-indazolo[2,1-b]phthalazinetriones [36][37][38][39][40][41][42][43][44][45][46][47][48][49][50]. A thorough scrutiny of the literature reveals that although various catalyst have been employed for the synthesis of 2H-indazolo[2,1-b]phthalazinetriones, the use of 5-sulphosalicylic acid remains ignored.…”