Polymeric membranes for biomedical applications

Woźniak-Budych, Marta J.

doi:10.1515/psr-2021-0052

Cited by 5 publications

(3 citation statements)

References 160 publications

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“…In response to question RQ1, in tissue engineering, the main properties exploited by the carotenoid are related to its antioxidant power, biocompatibility, antimicrobial activity and its ease of use in the composition of other products such as gels and polymeric membranes (Trombino et al, 2023;Woźniak-Budych, 2021). The studies identified investigated norbixin's properties in protective and healing coatings for wounds and in tissue repair and bone regeneration, as asked for in RQ2.…”

Section: The Pharmacological Activity Of Norbixin In Tissue Engineeringmentioning

confidence: 99%

A systematic literature review on the pharmacological applications of the carotenoid norbixin

Leal Alves,

Santos Miranda,

Leal Alves

et al. 2024

PRW

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Carotenoids play essential roles in human health and can fight and prevent diseases. One carotenoid that is currently attracting scientific interest, particularly for its antioxidant properties, is norbixin. Studies related to its use in the treatment of diseases have become increasingly present in the medical field. This systematic literature review aimed to investigate and gather studies on the pharmacological activity of norbixin for health benefits and the treatment of diseases. Four databases were consulted: Web of Science, PubMed, Scopus, and ScienceDirect. Articles were extracted using a combination of keywords such as 'norbixin', 'antioxidant', 'diseases', 'in vitro', 'in vivo', etc. A total of 173 articles were identified. After applying the inclusion and exclusion criteria, 21 were selected for inclusion in this review. Studies have shown that norbixin, alone or in combination with other treatments, may be effective in DNA protection, tissue engineering, bone repair, and the prevention and treatment of age-related macular degeneration and cardiovascular disease. These results provide a solid basis for further studies aimed at exploring the pharmacological properties of norbixin and enabling its use in therapeutic applications.

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Section: The Pharmacological Activity Of Norbixin In Tissue Engineeringmentioning

confidence: 99%

A systematic literature review on the pharmacological applications of the carotenoid norbixin

Leal Alves,

Santos Miranda,

Leal Alves

et al. 2024

PRW

View full text Add to dashboard Cite

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“…Membranes are defined as porous films that act as a separating barrier between two adjacent phases, capable of allowing the transport of substances from one phase to another in a selective manner [ 14 , 15 ]. In general, membranes utilized in the biomedical field can be used in tissue engineering, with a role in purification and in obtaining implants and scaffolds, in obtaining controlled release systems of active substances and in diagnosis, in the form of sensors and various diagnostic tests [ 16 ]. Membranes are classified according to their nature into natural membranes and artificial membranes.…”

Section: Introductionmentioning

confidence: 99%

Polymeric Membranes for Biomedical Applications

2023

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Polymeric membranes are selective materials used in a wide range of applications that require separation processes, from water filtration and purification to industrial separations. Because of these materials’ remarkable properties, namely, selectivity, membranes are also used in a wide range of biomedical applications that require separations. Considering the fact that most organs (apart from the heart and brain) have separation processes associated with the physiological function (kidneys, lungs, intestines, stomach, etc.), technological solutions have been developed to replace the function of these organs with the help of polymer membranes. This review presents the main biomedical applications of polymer membranes, such as hemodialysis (for chronic kidney disease), membrane-based artificial oxygenators (for artificial lung), artificial liver, artificial pancreas, and membranes for osseointegration and drug delivery systems based on membranes.

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“…The use of membranes has become increasingly established in the biomedical field, and particularly in tissue engineering, with the realization of biological purification systems, protective coatings for wounds that accelerate healing, systems for diagnosis and therapy through the controlled release of active substances [ 10 ], and scaffolds. Scaffolds are the main resource of tissue engineering, which is concerned with restoring the functionality of damaged tissues and organs.…”

Section: Introductionmentioning

confidence: 99%

Polymeric Based Hydrogel Membranes for Biomedical Applications

et al. 2023

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The development of biomedical applications is a transdisciplinary field that in recent years has involved researchers from chemistry, pharmacy, medicine, biology, biophysics, and biomechanical engineering. The fabrication of biomedical devices requires the use of biocompatible materials that do not damage living tissues and have some biomechanical characteristics. The use of polymeric membranes, as materials meeting the above-mentioned requirements, has become increasingly popular in recent years, with outstanding results in tissue engineering, for regeneration and replenishment of tissues constituting internal organs, in wound healing dressings, and in the realization of systems for diagnosis and therapy, through the controlled release of active substances. The biomedical application of hydrogel membranes has had little uptake in the past due to the toxicity of cross-linking agents and to the existing limitations regarding gelation under physiological conditions, but now it is proving to be a very promising field This review presents the important technological innovations that the use of membrane hydrogels has promoted, enabling the resolution of recurrent clinical problems, such as post-transplant rejection crises, haemorrhagic crises due to the adhesion of proteins, bacteria, and platelets on biomedical devices in contact with blood, and poor compliance of patients undergoing long-term drug therapies.

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Polymeric membranes for biomedical applications

Cited by 5 publications

References 160 publications

A systematic literature review on the pharmacological applications of the carotenoid norbixin

A systematic literature review on the pharmacological applications of the carotenoid norbixin

Polymeric Membranes for Biomedical Applications

Polymeric Based Hydrogel Membranes for Biomedical Applications

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