Polymeric nanoencapsulation of insect repellent: Evaluation of its bioefficacy on Culex quinquefasciatus mosquito population and effective impregnation onto cotton fabrics for insect repellent clothing

Balaji, A.P.B.; Ashu, Abhijeet; Manigandan, Subramani; Sastry, T. P.; Mukherjee, Amitava; Chandrasekaran, Natarajan

doi:10.1016/j.jksus.2016.12.005

Cited by 32 publications

(7 citation statements)

References 38 publications

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“…The surrounding layer formed by chitosan in nanoparticles could help protect the essential oil from the detoxifying enzymes inside the insect body [77, 78]. This protective role played by the encapsulating polymer probably supports the prolonged larvicidal effects observed in our study, as it enabled the protection of the insecticide from degradation and volatilization [80–82].…”

Section: Discussionsupporting

confidence: 59%

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Prolonged mosquitocidal activity of Siparuna guianensis essential oil encapsulated in chitosan nanoparticles

et al. 2019

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Background The use of synthetic insecticides is one of the most common strategies for controlling disease vectors such as mosquitos. However, their overuse can result in serious risks to human health, to the environment, as well as to the selection of insecticidal resistant insect strains. The development of efficient and eco-friendly insect control is urgent, and essential oils have been presented as potential alternatives to synthetic insecticides. Moreover, nanoencapsulation techniques can enhance their efficiency by protecting from degradation and providing a controlled release rate. Results We assessed the potential of chitosan nanoparticles in encapsulating Siparuna guianensis essential oil, and maintaining its efficiency and prolonging its activity for the control of Aedes aegypti larvae. The encapsulation was characterized by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA), with an encapsulation efficiency ranging from 84.8% to 88.0%. Toxicity studies have demonstrated efficacy against mosquito larvae over 50% for 19 days with 100% mortality during the first week. This persistent action is presumably due to the enhanced contact and slow and maintained release conferred by chitosan nanoparticles. Furthermore, the exposure of aquatic non-target organisms (e.g. embryos and small adult fishes) revealed adequate selectivity of these nanoparticles. Conclusions The encapsulation of S . guianensis essential oil in chitosan nanoparticles showed promising potential as a larvicide control alternative and should be considered within strategies for fighting Ae . aegypti .

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Section: Discussionsupporting

confidence: 59%

“…This small size may also enhance the contact and action of the active components of the essential oil at their action target [28, 75]. Similarly enhanced penetration into cells was previously reported for nano-encapsulated insecticides [76–78].…”

Section: Discussionsupporting

confidence: 56%

Prolonged mosquitocidal activity of Siparuna guianensis essential oil encapsulated in chitosan nanoparticles

et al. 2019

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“…Various studies have looked into the toxicity or insect-repellent effects of nanopesticides on flying target organisms such as A. aegypti [ 118 ], C. tritaeniorhynchus [ 118 ], C. pipiens [ 127 ], C. quinquefasciatus [ 128 ], Spodoptera littoralis [ 129 ], and Blattella germanica (German cockroach) [ 130 ]. However, more research is needed to assess the risk of nanopesticides on non-target air organisms—particularly those that feed on agricultural products (e.g., honeybees and other vital pollinators).…”

Section: Discussionmentioning

confidence: 99%

Hazard Assessment of the Effects of Acute and Chronic Exposure to Permethrin, Copper Hydroxide, Acephate, and Validamycin Nanopesticides on the Physiology of Drosophila: Novel Insights into the Cellular Internalization and Biological Effects

Demir

Kansız

Doğan

et al. 2022

IJMS

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New insights into the interactions between nanopesticides and edible plants are required in order to elucidate their impacts on human health and agriculture. Nanopesticides include formulations consisting of organic/inorganic nanoparticles. Drosophila melanogaster has become a powerful model in genetic research thanks to its genetic similarity to mammals. This project mainly aimed to generate new evidence for the toxic/genotoxic properties of different nanopesticides (a nanoemulsion (permethrin nanopesticides, 20 ± 5 nm), an inorganic nanoparticle as an active ingredient (copper(II) hydroxide [Cu(OH)2] nanopesticides, 15 ± 6 nm), a polymer-based nanopesticide (acephate nanopesticides, 55 ± 25 nm), and an inorganic nanoparticle associated with an organic active ingredient (validamycin nanopesticides, 1177 ± 220 nm)) and their microparticulate forms (i.e., permethrin, copper(II) sulfate pentahydrate (CuSO4·5H2O), acephate, and validamycin) widely used against agricultural pests, while also showing the merits of using Drosophila—a non-target in vivo eukaryotic model organism—in nanogenotoxicology studies. Significant biological effects were noted at the highest doses of permethrin (0.06 and 0.1 mM), permethrin nanopesticides (1 and 2.5 mM), CuSO4·5H2O (1 and 5 mM), acephate and acephate nanopesticides (1 and 5 mM, respectively), and validamycin and validamycin nanopesticides (1 and 2.5 mM, respectively). The results demonstrating the toxic/genotoxic potential of these nanopesticides through their impact on cellular internalization and gene expression represent significant contributions to future nanogenotoxicology studies.

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“…The most effective synthetic repellents are DEET (N,N-diethyl-m-toluamide) and IR3535 (3-(NButyl-N-acetyl)-aminopropionic acid [97]. Several nanoparticles synthesised and successfully impregnated into cotton fabrics in insect-repellent clothing show high efficacy against mosquito larvae and adult populations, which gives them the potential to be used as eco-friendly approaches to control mosquitoes if applied in long-lasting insect-repellent clothing [98,99]. The fact that the use of synthetic repellents causes insecticide resistance in mosquitoes, has a harmful effect on non-target organisms, and threatens the environment has led to widespread discussions around this method of control [97].…”

Section: Mosquito Repellentsmentioning

confidence: 99%

Mosquito-Borne Diseases Emergence/Resurgence and How to Effectively Control It Biologically

2020

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Deadly pathogens and parasites are transmitted by vectors and the mosquito is considered the most threatening vector in public health, transmitting these pathogens to humans and animals. We are currently witnessing the emergence/resurgence in new regions/populations of the most important mosquito-borne diseases, such as arboviruses and malaria. This resurgence may be the consequence of numerous complex parameters, but the major cause remains the mismanagement of insecticide use and the emergence of resistance. Biological control programmes have rendered promising results but several highly effective techniques, such as genetic manipulation, remain insufficiently considered as a control mechanism. Currently, new strategies based on attractive toxic sugar baits and new agents, such as Wolbachia and Asaia, are being intensively studied for potential use as alternatives to chemicals. Research into new insecticides, Insect Growth Regulators, and repellent compounds is pressing, and the improvement of biological strategies may provide key solutions to prevent outbreaks, decrease the danger to at-risk populations, and mitigate resistance.Pathogens 2020, 9, 310 2 of 26 are not used at all, and those that are still in the test or design phase but are very promising, which we suggest to be considered in the biological control of mosquito-borne diseases.

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Polymeric nanoencapsulation of insect repellent: Evaluation of its bioefficacy on Culex quinquefasciatus mosquito population and effective impregnation onto cotton fabrics for insect repellent clothing

Cited by 32 publications

References 38 publications

Prolonged mosquitocidal activity of Siparuna guianensis essential oil encapsulated in chitosan nanoparticles

Prolonged mosquitocidal activity of Siparuna guianensis essential oil encapsulated in chitosan nanoparticles

Hazard Assessment of the Effects of Acute and Chronic Exposure to Permethrin, Copper Hydroxide, Acephate, and Validamycin Nanopesticides on the Physiology of Drosophila: Novel Insights into the Cellular Internalization and Biological Effects

Mosquito-Borne Diseases Emergence/Resurgence and How to Effectively Control It Biologically

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