Polymeric nanomaterials in drug delivery

Bajpai, A. K.; Saini, Rajesh K.

doi:10.1016/b978-0-12-814657-6.00010-0

Cited by 3 publications

(1 citation statement)

References 104 publications

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“…The most challenging and important parameters required to be considered in drug delivery systems that should be considered such as pressure, enzymatic activity [6], pH [7], solubility, molecular size and reticuloendothelial system [8]. The aim of drug targeting has always been to direct the drug to the target tissue either at a cellular level or subcellular level where its activity is required [1,4,9,10]. This paper presents two new coating formulations in existing drug delivery systems: the first one is for A. platensis tablets, where a double layer of polymers [11] will be added on top of the core.…”

Section: Introductionmentioning

confidence: 99%

Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes

et al. 2022

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Arthrospira platensis (A. platensis) aqueous extract has massive amounts of natural products that can be used as future drugs, such as C-phycocyanin, allophycocyanin, etc. This extract was chosen because of its high adaptability, which reflects its resolute genetic composition. The proactive roles of cyanobacteria, particularly in the medical field, have been discussed in this review, including the history, previous food and drug administration (FDA) reports, health benefits and the various dosedependent therapeutic functions that A. platensis possesses, including its role in fighting against lethal diseases such as cancer, SARS-CoV-2/COVID-19, etc. However, the remedy will not present its maximal effect without the proper delivery to the targeted place for deposition. The goal of this research is to maximize the bioavailability and delivery efficiency of A. platensis constituents through selected sites for effective therapeutic outcomes. The solutions reviewed are mainly on parenteral and tablet formulations. Moreover, suggested enteric polymers were discussed with minor composition variations applied for better storage in high humid countries alongside minor variations in the polymer design were suggested to enhance the premature release hindrance of basic drugs in low pH environments. In addition, it will open doors for research in delivering active pharmaceutical ingredients (APIs) in femtoscale with the use of various existing and new formulations.

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Section: Introductionmentioning

confidence: 99%

Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes

et al. 2022

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Development and Synthesis of Block Co-polymer and their Role in Nanotechnology

Gautam,

Kaurav,

Kanwar

et al. 2023

Block Co-Polymeric Nanocarriers: Design, Concept, and Therapeutic Applications

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Management of Energy Conversion Processes in Membrane Systems

et al. 2022

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The internal energy (U-energy) conversion to free energy (F-energy) and energy dissipation (S-energy) is a basic process that enables the continuity of life on Earth. Here, we present a novel method of evaluating F-energy in a membrane system containing ternary solutions of non-electrolytes based on the Kr version of the Kedem–Katchalsky–Peusner (K–K–P) formalism for concentration polarization conditions. The use of this formalism allows the determination of F-energy based on the production of S-energy and coefficient of the energy conversion efficiency. The K–K–P formalism requires the calculation of the Peusner coefficients Kijr and Kdetr (i, j ∈ {1, 2, 3}, r = A, B), which are necessary to calculate S-energy, the degree of coupling and coefficients of energy conversion efficiency. In turn, the equations for S-energy and coefficients of energy conversion efficiency are used in the F-energy calculations. The Kr form of the Kedem–Katchalsky–Peusner model equations, containing the Peusner coefficients Kijr and Kdetr, enables the analysis of energy conversion in membrane systems and is a useful tool for studying the transport properties of membranes. We showed that osmotic pressure dependences of indicated Peusner coefficients, energy conversion efficiency coefficient, entropy and energy production are nonlinear. These nonlinearities were caused by pseudophase transitions from non-convective to convective states or vice versa. The method presented in the paper can be used to assess F-energy resources. The results can be adapted to various membrane systems used in chemical engineering, environmental engineering or medical applications. It can be used in designing new technologies as a part of process management.

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Polymeric nanomaterials in drug delivery

Cited by 3 publications

References 104 publications

Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes

Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes

Development and Synthesis of Block Co-polymer and their Role in Nanotechnology

Management of Energy Conversion Processes in Membrane Systems

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