Polymerization of Poly(Itaconic Acid) on Surfaces by Atom Transfer Radical Polymerization in Aqueous Solution

Sankhe, Amit Y.; Husson, Scott M.; Kilbey, S. Michael

doi:10.1557/proc-710-dd14.12.1

Cited by 5 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Using our previously described − polymerization methodology, we prepared highly uniform, nanothin films of poly(2-vinylpyridine) (PVP), polystyrene (PS), and poly(1-benzyl-2-vinylpyridinium bromide) (BzPVP) on gold biosensor chips and measured values of Δ G ad for individual amino acid residues adsorbing onto these film surfaces from solutions near physiological pH. The choice of PVP and BzPVP allowed us to study the effect of surface charge on peptide adsorption.…”

Section: Introductionmentioning

confidence: 99%

Adsorption Thermodynamics of Short-Chain Peptides on Charged and Uncharged Nanothin Polymer Films

Singh

Husson

2006

Langmuir

Self Cite

View full text Add to dashboard Cite

The present work describes experimental measurements of submolecular-level interaction energies involved in the process of peptide adsorption on polymer films using surface plasmon resonance spectroscopy. Gibbs energy change on adsorption (DeltaG(ad)) for tyrosine, phenylalanine, and glycine homopeptides were measured at 25 degrees C and pH 7 on highly uniform, nanothin polymer films, and the results were used to predict DeltaG(ad) for homologous homopeptides with a larger number of residue units. Nanothin poly(2-vinylpyridine), poly(styrene), and poly(1-benzyl-2-vinylpyridinium bromide) films were used for the adsorption studies; they were prepared using a graft polymerization methodology. In-situ swelling experiments were done with ellipsometry to examine the uniformity of the surfaces and to ensure that the graft densities of the different polymer films were similar to facilitate the comparison of adsorption results on these surfaces. The swelling experiments showed that the films were uniform, and the grafting densities were found to be 0.14-0.17 chains/nm(2). For uncharged surfaces, predicted and measured DeltaG(ads) values for homopeptides deviated by < or =4.9%. To extend this approach to a mixed-residue peptide, measurements were made for glycine, phenylalanine, and tyrosine-leucine subunits found in leucine enkephalin. The predicted DeltaG(ads) values for leucine enkephalin deviated by 3.0% and -9.1% for poly(2-vinylpyridine) and poly(styrene) films, respectively. Deviations between measured and predicted adsorption energies were larger for the charged poly(1-benzyl-2-vinylpyridinium bromide) surface relative to uncharged surfaces. While the adsorption energies were found to be additive within experimental uncertainties for the charged surface, generally speaking, measured uncertainty values were also larger for the charged surface.

show abstract

Section: Introductionmentioning

confidence: 99%

Adsorption Thermodynamics of Short-Chain Peptides on Charged and Uncharged Nanothin Polymer Films

Singh

Husson

2006

Langmuir

Self Cite

View full text Add to dashboard Cite

show abstract

“…Using our previously described ,, polymerization methodology, we prepared a highly uniform, nanothin film of poly(2-vinylpyridine) on a gold biosensor chip and measured values of Δ G ad for individual amino acid residues adsorbing onto this film surface from solutions that mimic physiological conditions. The SPR analysis method allowed us to check whether adsorption hysteresis existed and to what extent, if any, were the model short-chain peptides bound irreversibly to the surface.…”

Section: Introductionmentioning

confidence: 99%

Thermodynamic Measurements and Predictions of the Adsorption of Short-Chain Peptides on Nanothin Polymer Films

Singh

Husson

2004

Biomacromolecules

Self Cite

View full text Add to dashboard Cite

This contribution describes experimental measurements of submolecular-level interaction energies involved in the process of peptide adsorption on polymer films. The objective of this study was to use surface plasmon resonance (SPR) spectroscopy to measure the Gibbs energy change on adsorption (DeltaG(ad)) for pairs of various homopeptides on highly uniform, nanothin polymer films and to use these data, along with the principle of additivity, to predict DeltaG(ad) for homologous homopeptides, as well as for a mixed-residue peptide. By using a graft polymerization methodology, a nanothin poly(2-vinylpyridine) film was prepared and adsorption energies were measured first for a homologous series of tyrosine (Y) homopeptides on this film to determine submolecular-level interaction energies. By using SPR, adsorption isotherms were measured for YY and YYY peptides; analysis of these isotherms provided DeltaG(ad) data for a midchain tyrosine unit and a set of chain-end tyrosine units; values were -0.75 +/- 0.07 kcal/mol and -2.12 +/- 0.04 kcal/mol, respectively. Combining the thermodynamic contributions for adsorption of individual tyrosine units allowed a predictive estimate of -5.12 +/- 0.32 kcal/mol for the adsorption energy for YYYYYY; this estimate deviated by only 2.3% from its measured value of -5.24 +/- 0.06 kcal/mol. Similarly, adsorption energies were found for phenylalanine, glycine, and tyrosine-leucine peptides. Combining the thermodynamic contributions for adsorption of individual residue units allowed a predictive estimate of -3.24 +/- 0.38 kcal/mol for a pentapeptide, leucine enkephalin; this estimate deviated by only 3.0% from its measured value of -3.34 +/-0.11 kcal/mol.

show abstract

“…[ 204 ] SI‐ATRP was employed to grow PIA brushes from gold surfaces in aqueous solutions, which were patterned via self‐assembled monolayers (SAMs) of 11‐mercapto‐undecanol functionalized with 4‐(chloromethyl) benzoyl chloride initiator. [ 205 ] N ‐phenylitaconimide was polymerized by ICAR ATRP catalyzed by FeBr 3 , then the polymer was used as a macroinitiator to form a copolymer with styrene, [ 206 ] and homopolymers of dimethyl itaconate [ 207 ] and their copolymers with acrylonitrile by ARGET ATRP. [ 208 ] Thus, biomass‐derived monomers were effectively paired with greener synthetic conditions, such as low catalyst loadings and benign Fe‐based catalysts.…”

Section: The 12 Principles Of Green Chemistry and Their Implementatio...mentioning

confidence: 99%

Toward Green Atom Transfer Radical Polymerization: Current Status and Future Challenges

et al. 2022

View full text Add to dashboard Cite

Dedicated to Professor Klaus Muellen on the occasion of his 75th birthdayReversible-deactivation radical polymerizations (RDRPs) have revolutionized synthetic polymer chemistry. Nowadays, RDRPs facilitate design and preparation of materials with controlled architecture, composition, and functionality. Atom transfer radical polymerization (ATRP) has evolved beyond traditional polymer field, enabling synthesis of organic-inorganic hybrids, bioconjugates, advanced polymers for electronics, energy, and environmentally relevant polymeric materials for broad applications in various fields. This review focuses on the relation between ATRP technology and the 12 principles of green chemistry, which are paramount guidelines in sustainable research and implementation. The green features of ATRP are presented, discussing the environmental and/or health issues and the challenges that remain to be overcome. Key discoveries and recent developments in green ATRP are highlighted, while providing a perspective for future opportunities in this area.

show abstract

Polymerization of Poly(Itaconic Acid) on Surfaces by Atom Transfer Radical Polymerization in Aqueous Solution

Cited by 5 publications

References 7 publications

Adsorption Thermodynamics of Short-Chain Peptides on Charged and Uncharged Nanothin Polymer Films

Adsorption Thermodynamics of Short-Chain Peptides on Charged and Uncharged Nanothin Polymer Films

Thermodynamic Measurements and Predictions of the Adsorption of Short-Chain Peptides on Nanothin Polymer Films

Toward Green Atom Transfer Radical Polymerization: Current Status and Future Challenges

Contact Info

Product

Resources

About