The success of the future exploitation of the Pacific polymetallic nodule deposits depends on an accurate estimation of their resources, especially in small batches, scheduled for extraction in the short term. The estimation based only on the results of direct seafloor sampling using box corers is burdened with a large error due to the long sampling interval and high variability of the nodule abundance. Therefore, estimations should take into account the results of bottom photograph analyses performed systematically and in large numbers along the course of a research vessel. For photographs taken at the direct sampling sites, the relationship linking the nodule abundance with the independent variables (the percentage of seafloor nodule coverage, the genetic types of nodules in the context of their fraction distribution, and the degree of sediment coverage of nodules) was determined using the general linear model (GLM). Compared to the estimates obtained with a simple linear model linking this parameter only with the seafloor nodule coverage, a significant decrease in the standard prediction error, from 4.2 to 2.5 kg/m2, was found. The use of the GLM for the assessment of nodule abundance in individual sites covered by bottom photographs, outside of direct sampling sites, should contribute to a significant increase in the accuracy of the estimation of nodule resources.