Polymorphic effects of FABP4 and SCD genes on intramuscular fatty acid profiles in longissimus muscle from two cattle breeds

Dujková, R.; Ranganathan, Yuvaraj; Dufek, A.; Macák, J; Bezdíček, Jiří

doi:10.2754/avb201584040327

Cited by 10 publications

(16 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They concluded that SCD is one of the causes of genotype variation [200]. In contrast, SCD (878C>T) SNP was observed to have no association with FA profile in upper sirloin cuts of Aberdeen Angus and Blonde d'Aquitaine cattle [112].…”

Section: Stearoyl-coa Desaturase (Scd)mentioning

confidence: 98%

“…Beef fat is primarily categorized into three; subcutaneous, intermuscular and intramuscular fat [112]. Saturated FA (SFA) whose levels are high in ruminant meat due to hydrogenation of dietary unsaturated FA in the rumen, are associated with health risks such as coronary heart disease [113,114], although this association remains controversial [115,116].…”

Section: Meat Characteristicsmentioning

confidence: 99%

“…At low levels, skatoles contribute to desirable odours and flavours, but at high levels, they produce a nauseating faecal odour [110,111]. Finishing grass-fed cattle with concentrate diet for at least 54 days reduces pastoral flavour significantly [112].…”

Section: Flavourmentioning

confidence: 99%

“…Several genes are reported to be responsible for variation in fat content and FA composition in beef. The genes encode for cocaine-and amphetamine-regulated transcript [188], leptin [189], diacylglycerol O-acyltransferase, the growth hormone 1 [190] sterol regulatory element-binding protein 1 [191], fatty acid synthase, stearoyl-CoA desaturase and fatty acid binding protein 4 [112,[192][193][194]. This review will focus on fatty acid synthase, stearoyl-CoA desaturase and fatty acid binding protein 4 genes.…”

Section: Genes That Influence Carcass Fat Content and Fatty Acid Profmentioning

confidence: 99%

“…Blonde cattle CC genotype had higher arachidonic acid and EPA, but lower oleic acid and total SFA than the CG. The GG genotype was observed in only one bull [112]. g.7516G > C polymorphisms were analyzed for association with marbling score and subcutaneous fat depth in Wagyu x Limousin crosses.…”

Section: Fatty Acid Binding Protein 4 (Fabp4)mentioning

confidence: 99%

See 4 more Smart Citations

Diet and Genetics Influence Beef Cattle Performance and Meat Quality Characteristics

Mwangi

Charmley

Gardiner

et al. 2019

Foods

View full text Add to dashboard Cite

A comprehensive review of the impact of tropical pasture grazing, nutritional supplementation during feedlot finishing and fat metabolism-related genes on beef cattle performance and meat-eating traits is presented. Grazing beef cattle on low quality tropical forages with less than 5.6% crude protein, 10% soluble starches and 55% digestibility experience liveweight loss. However, backgrounding beef cattle on high quality leguminous forages and feedlot finishing on high-energy diets increase meat flavour, tenderness and juiciness due to improved intramuscular fat deposition and enhanced mono- and polyunsaturated fatty acids. This paper also reviews the roles of stearoyl-CoA desaturase, fatty acid binding protein 4 and fatty acid synthase genes and correlations with meat traits. The review argues that backgrounding of beef cattle on Desmanthus, an environmentally well-adapted and vigorous tropical legume that can persistently survive under harsh tropical and subtropical conditions, has the potential to improve animal performance. It also identifies existing knowledge gaps and research opportunities in nutrition-genetics interactions aimed at a greater understanding of grazing nutrition, feedlot finishing performance, and carcass traits of northern Australian tropical beef cattle to enable red meat industry players to work on marbling, juiciness, tenderness and overall meat-eating characteristics.

show abstract

Section: Stearoyl-coa Desaturase (Scd)mentioning

confidence: 98%

Section: Meat Characteristicsmentioning

confidence: 99%

Section: Flavourmentioning

confidence: 99%

Section: Genes That Influence Carcass Fat Content and Fatty Acid Profmentioning

confidence: 99%

Section: Fatty Acid Binding Protein 4 (Fabp4)mentioning

confidence: 99%

See 3 more Smart Citations

Diet and Genetics Influence Beef Cattle Performance and Meat Quality Characteristics

Mwangi

Charmley

Gardiner

et al. 2019

Foods

View full text Add to dashboard Cite

show abstract

Candidate genes and fatty acids in beef meat, a review

Pećina

Ivanković

2021

Italian Journal of Animal Science

View full text Add to dashboard Cite

Identification of High and Low Branched-Chain Fatty Acid–Producing Phenotypes in Holstein Cows following High-Forage and Low-Forage Diets in a Crossover Designed Trial

Picklo

Kalscheur

Magnuson

et al. 2022

Current Developments in Nutrition

View full text Add to dashboard Cite

Background Branched chain fatty acids (BCFA) are rumen-derived fatty acids comprising about 2% of bovine milk fatty acids. BCFA possess anti-inflammatory properties and enriching the BCFA content of bovine milk may provide human health benefits. Objective We determined whether forage content impacts the BCFA content of milk from Holstein cows and identified fatty acid phenotypes in high vs low BCFA-containing milks. Methods Holstein cows (n = 62), fed for 67 days in a cross-over design, consumed a diet with high forage and low concentrate (HF:C) and a diet with low forage and high concentrate (LF:C). Milk samples were collected at the end of each treatment period and fatty acid content determined. Paired t-tests, one-way ANOVA, sparse partial least squares discriminant analysis (sPLSDA), and Pearson's correlation analysis were used to analyze the data. Results The total milk fatty acid concentration for cows fed the HF:C diet was greater than that of cows fed the LF:C diet (4.2 ± 0.7 g/100 mL vs 3.9 ± 0.9 g/100 mL). sPLSDA demonstrated separation of the dietary treatments, with BCFA and odd-chain fatty acids as primary determinants. Total BCFA content in milk fatwas elevated by HF:C intake vs LF:C intake (1.80 vs 1.68%). Quintile separation of high vs low BCFA milks resulted in 4 groups, HF:C /low BCFA, HF:C /high BCFA; LF:C /low BCFA, and LF:C /high BCFA. Milks from the high BCFA quintiles had lower palmitic acid content (29.6% vs 34.4%) but higher oleic acid content than milks from the low BCFA quintiles (19.7% vs 17.0%). Some cows were identified as high BCFA producers or low BCFA producers regardless of diet. Conclusions BCFA content of milk is diet-sensitive but variation in responses exists. The potential to produce milk with high BCFA content and lower SFA content needs further study. Summary Branched chain fatty acid (BCFA) content of milk from Holstein cows is diet-sensitive but modified by other factors. BCFA content is negatively associated with palmitic acid content in milk fat.

show abstract

Polymorphic effects of FABP4 and SCD genes on intramuscular fatty acid profiles in longissimus muscle from two cattle breeds

Cited by 10 publications

References 19 publications

Diet and Genetics Influence Beef Cattle Performance and Meat Quality Characteristics

Diet and Genetics Influence Beef Cattle Performance and Meat Quality Characteristics

Candidate genes and fatty acids in beef meat, a review

Identification of High and Low Branched-Chain Fatty Acid–Producing Phenotypes in Holstein Cows following High-Forage and Low-Forage Diets in a Crossover Designed Trial

Contact Info

Product

Resources

About