Polymorphism of PIT-1 and Prolactin Genes and Their Effects on Milk Yield in Holstein Frisian Dairy Cows Bred in Vietnam

Thuy, N. T. D.; Thu, N. T.; Cuong, Nguyen Huu; Ty, Lee; Nguyen, Thu Thi; Khoa, Do Vo Anh

doi:10.1134/s1022795418030146

Cited by 22 publications

(15 citation statements)

References 21 publications

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“…Significant differences in daily milk yield (P<0.05) of the Holstein breeding cows in favor of animals with AA genotype of PIT1 gene were revealed compared to the analogues of AB and BB genotypes. The results of studies showing off the genotypes association of PIT1 gene with indicators of milk productivity, conducted on the Holstein breeding cows in Vietnam, are similar to the results of other studies [11]. The same tendency (AA> AB>BB) in daily milk yield was found among cows of the local breed of Iraqi cattle with different genotypes of PIT1 gene [12].…”

Section: Introductionsupporting

confidence: 75%

Evaluation towards stud bulls with different mixed genotypes relating to somatotropin cascade genes by origin

Zagidullin¹,

Gilemhanov²,

Хисамов³

et al. 2020

BIO Web Conf.

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A preliminary evaluation towards a breeding value of the Holstein breeding bulls with different genotypes of somatotropin cascade genes is presented: pituitary transcription factor or growth hormone factor (PIT1), prolactin (PRL), somatotropin (GH), somatotropin releasing hormone (GHRH), insulin-like (IGF-1) in the conditions of the Republic of Tatarstan. The research studies the signs (indices) of milk productivity (milk yield and fat in milk) of the closest female ancestors of bulls with different genotypes of somatotropin cascade genes. Studies and analysis have shown that the bulls with the mixed genotypes ABAALLBBAA (10269 kg), AAAALLBBAB (4.13 %) and BBAALLABBB (9402 kg and 4.06 %) had the highest and optimum evaluation by origin, judging by the bulls’ pedigree (geneological) index. The frequency to meet bulls with the desired mixed genotypes was low and amounted to 4.28–5.71 %.

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Section: Introductionsupporting

confidence: 75%

Evaluation towards stud bulls with different mixed genotypes relating to somatotropin cascade genes by origin

Zagidullin¹,

Gilemhanov²,

Хисамов³

et al. 2020

BIO Web Conf.

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“…Research focuses on analyzing the relationship between the values of these traits and polymorphic variants of different genes. The genes encoding different proteins, such as milk proteins, enzymes involved in the metabolism of fatty acids, proteins binding and transporting fatty acids, some hormones, transcription factors and many others are analyzed in this aspect [Szewczuk et al 2011, Cieślińska et al 2019, Thuy et al 2018, Kiyici et al 2019.…”

Section: Resultsmentioning

confidence: 99%

Assessment of ANXA9 SNP effects on milk performance traits in Polish Holstein-Friesian cows

Kulig¹,

Wojdak-Maksymiec²,

Szewczuk³

2020

Acta Sci. Pol. Zootech.

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The aim of this study was to estimate associations between the ANXA9 951A/G polymorphism and milk performance traits (daily milk yield, protein yield, fat yield, protein content and fat content), as well as somatic cell count in milk in 990 Polish Holstein-Friesian cows. The statistical analysis confirmed its significance in shaping the analyzed traits. In most cases, the presence of the allele A was associated with a decrease in the values of the above traits, while in the first lactation a significant additive effect of this allele toward increasing the values of the daily milk yield and SCC was found.

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“…The Bovine PRL gene has been mapped to chromosome 23 at 43 cM close to QTL, about 10 kb in size, including 5 exons coding for 199 amino acids and 4 introns (Mahajan et al, 2012;Chauhan, 2017, andSamuel et al, 2023). Using polymerase chain reaction and the Rstriction Fragments Length Polymorphism technique (PCR-RFLP), these polymorphic structures of the PRL gene have been studied by many researchers, who confirmed significant associations between PRL polymorphic variants and milk production traits in dairy cattle (He et al, 2006;Hu et al, 2009;Mehmannavaz et al, 2009;Alfonso et al, 2012;César et al, 2012;Thuy et al, 2018, andIlie et al, 2023).…”

Section: Introductionmentioning

confidence: 98%

“…Due to the importance of this PRL candidate gene, most of the studies suggested that the PRL variants could be useful in selection programs for improving milk yield and its composition in dairy cattle (e.g. Bukhari et al, 2013;Deepika and Salar, 2014;Fontanesiet al, 2014;Sonmez and Ozdemir, 2017;Thuy et al, 2018;Dudule et al, 2020;Ozdemir, 2020, andShah et al, 2021). Recently, Ilie et al (2023) stated that the bovine PRL gene is essential for the initiation and maintenance of lactation and exerts multiple effects on mammary alveoli to promote the synthesis and secretion of major components of milk.…”

Section: Introductionmentioning

confidence: 99%

“…Based on recent worldwide molecular studies, strong associations among the PRL gene genotypes and milk traits were detected, emphasizing the potentiality of the PRL gene as a candidate gene to be used in selection for improving milk traits in dairy cattle (Alipanah et al, 2007;Lu et al, 2010;Alfonso et al, 2012;Cesar et al, 2012;Das et al, 2012;Mahajan et al, 2012;Bukhari et al, 2013;Patel and Chauhan, 2017;Thuy et al, 2018, andSamuel et al, 2023). But, the molecular studies practiced in developing countries concerning the associations of the PRL gene with milk traits in dairy cattle are limited and scarce.…”

Section: Introductionmentioning

confidence: 99%

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Detecting the Molecular Associations of Prolactin Gene Genotypes With Milk Traits in Friesian and Baladi Cows Using RFLP Technique

Khalil,

Iraqi,

Mohamed

et al. 2023

Egyptian Journal of Animal Production

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Four years of experimental work were conducted applying PCR-RFLP to detect the SNP polymorphic associations of the prolactin candidate gene (PRL) with milk traits in cattle. A total of 494 lactations for 180 milking cows of Friesian in Elkarda herd (FK) and Sakha herd (FS) and Baladi cows in Elserw herd (BS) were used. The PCR products were digested using NaeI and SmaI restricted enzymes to investigate the molecular associations of the PRL gene genotypes with milk traits.The highest expected numbers of alleles (NE) in CC, CD and DD genotypes of the PRL gene were recorded in the DD genotype in both Friesian and Baladi herds, while the lowest expected numbers were recorded in CC genotype in all herds. The highest NE in GG, GT and TT genotype was in the TT genotype and the lowest NE was in the GG genotype in all herds. PRL gene was not in Hardy-Weinberg Equilibrium in all herds. The allelic frequency for the D allele was much higher than the frequency of the C allele, while the frequency of the T allele was higher than the frequency of the G allele.The observed and expected values of heterozygosity for the PRL gene were mostly moderate in the three herds studied. The values of polymorphic information content (PIC) were mostly moderate in all herds. The values of fixation index (reduction in heterozygosity due to inbreeding, FIS) were high in the FK herd (0.82), FS herd (0.62) and BS herd (0.94).The molecular associations between PRL gene genotypes and milk traits indicate that the CD genotype of the PRL gene has strong molecular associations with yields of milk, fat and protein relative to CC and DD genotypes. GG genotype was significantly associated with all milk traits relative to GT and TT genotypes.

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Polymorphism of PIT-1 and Prolactin Genes and Their Effects on Milk Yield in Holstein Frisian Dairy Cows Bred in Vietnam

Cited by 22 publications

References 21 publications

Evaluation towards stud bulls with different mixed genotypes relating to somatotropin cascade genes by origin

Evaluation towards stud bulls with different mixed genotypes relating to somatotropin cascade genes by origin

Assessment of ANXA9 SNP effects on milk performance traits in Polish Holstein-Friesian cows

Detecting the Molecular Associations of Prolactin Gene Genotypes With Milk Traits in Friesian and Baladi Cows Using RFLP Technique

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