Polymorphism of Serum Proteins (C3, BF, HP and TF) of Six Populations in Colombia

Abstract

Five hundred and eighty-five serum samples from six populations in Colombia (Baranoa, Choco, Uitoto Indians, Subachoque, Pasto and Urban Bogotan) were investigated for four genetic markers. For the HP, C3 and BF systems but not for TF there is a wide range of gene frequency variation and these differences are compared with those in the few previous studies.

Genetic structure of Quechua-speakers of the Central Andes and geographic patterns of gene frequencies in South Amerindian populations

“…However, this population seems to have higher frequencies of the Rh(cDe) and Rh(CDe) alleles than other Quechua-speaking groups, as well as higher values of the Ns and Gc1 types and the Gc1F subtype than other Andean native populations (Quechua or Aymara). In this paper, we provide new data about some polymorphic serum proteins infrequently studied in Native American populations: Bf, C3 (Haas et al, 1985;Bernal et al, 1989), and Pi (Goedde et al, 1985;Marini et al, 1993). These are the only data reported for Central Andean peoples.…”

HLA Antigens in Five Amerindian Groups (Yuko, Bari, Tunebo, Guane and Paez) of Colombia: Results of ‘&Egr;xpedición Humana’

“…The studies about genetic variability among the Indian populations of Colombia were started by Kirk et al [2]; however, more recently several surveys analysed various ge netic markers in different urban and Amerin dian groups [3][4][5], In Colombia, the genes of the major histocompatibility complex (HLA) have been the subject of four studies, but only three Indian groups, Uitoto, Awa-Kwaikerand Chimila, have been investigated [6][7][8], In 1988 the Universidad Javeriana launched a 5-year programme 'Expedición Humana' in which several Amerindian groups have been simulta neously studied for immunogenetic markers specially for the HLA-A, B, C and D loci. The present study reports the frequency variation among five Amerindian populations, three in habiting the northeast border between Colom bia and Venezuela (Yuko, Tunebo and Bari), while the other two (Guane and Paez) occupy a more central region of the country.…”