Polymorphism of somatotropin, prolactin, leptin, and thyreoglobulin genes in bulls

Tyulkin, S.V.; Ахметов, Т. М.; Валиуллина, Э. Ф.; Vafin, R. R.

doi:10.1134/s2079059713030118

Cited by 12 publications

(8 citation statements)

References 5 publications

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“…According to Tiul'kin et al [16], 62.9% of purebred and crossbred Holstein bulls have the TG5 CC , 35.7% possess the TG5 СT , and only 1.4% have the TG5 TT genotype. No animals with the TG5 TT genotype were found in a herd of Black-and-White Holstein cows.…”

Section: Resultsmentioning

confidence: 99%

“…In fact, a single-nucleotide polymorphism located in the 5′ untranslated region of this gene is used for marker-based selection aimed at increasing marbling [10]. Several studies have revealed an association between thyroglobulin gene polymorphism and fat metabolism, particularly intramuscular fat [11][12][13][14][15], as well as milk yield and quality [11,16,17]. Thus, cows of the Kholmogorsky breed of the Tatarstan type carrying the TG5 СТ and TG5 ТТ genotypes surpassed their age equals carrying the TG5 СС genotype regarding milk yield and mass fraction of fat in milk.…”

Section: Introductionmentioning

confidence: 99%

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Effect of the bovine TG5 gene polymorphism on milk- and meat-producing ability

et al. 2020

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Aim: This study aimed to determine the effect of thyroglobulin (TG5) gene polymorphism on milk and meat productivity in the various cattle breeds currently bred in the Republic of Bashkortostan. Materials and Methods: The test was performed on dairy cattle of Black-and-White, Bestuzhev, and Simmental breeds, and meat cattle of Hereford and limousine breeds. The purpose of the test was to search for associations between the polymorphic alleles of the thyroglobulin (TG5) gene and economically useful traits. Results: All studied breeds showed a frequency predominance of the TG5C allele (from 0.56 to 0.71). A clear trend of an effect of the genotypes of the TG5 gene on milk-productivity indicators was revealed; cows with the TG5TT genotype have the highest milk yield and fat content in milk. The milk of cows of Bestuzhev and Simmental breeds that possessed this genotype was also characterized by higher protein content. Conclusion: We identified an effect of the polymorphism of the TG5 gene in the Hereford and limousine breeds on fat metabolism intensity indicators, such as fat output and fat content, in the longissimus muscle and in the general sample of ground beef.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of the bovine TG5 gene polymorphism on milk- and meat-producing ability

et al. 2020

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“…At present, molecular genetics acts as the most diverse approaches and methods to be applied in animal husbandry, including testing breeding animals, their selection that depends on the genetic variants of productivity, diagnosis of hereditary diseases, research on the diversity and genetic structure of a herd, editing the genome and more [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Evaluation towards stud bulls with different mixed genotypes relating to somatotropin cascade genes by origin

Zagidullin¹,

Gilemhanov²,

Хисамов³

et al. 2020

BIO Web Conf.

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A preliminary evaluation towards a breeding value of the Holstein breeding bulls with different genotypes of somatotropin cascade genes is presented: pituitary transcription factor or growth hormone factor (PIT1), prolactin (PRL), somatotropin (GH), somatotropin releasing hormone (GHRH), insulin-like (IGF-1) in the conditions of the Republic of Tatarstan. The research studies the signs (indices) of milk productivity (milk yield and fat in milk) of the closest female ancestors of bulls with different genotypes of somatotropin cascade genes. Studies and analysis have shown that the bulls with the mixed genotypes ABAALLBBAA (10269 kg), AAAALLBBAB (4.13 %) and BBAALLABBB (9402 kg and 4.06 %) had the highest and optimum evaluation by origin, judging by the bulls’ pedigree (geneological) index. The frequency to meet bulls with the desired mixed genotypes was low and amounted to 4.28–5.71 %.

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“…The biological effect of the growth hormone gene (GH) consists in regula-tion and stimulation of many metabolic processes. The hormone (somatotropin) controlled by GH is produced by the anterior lobe of the hypophysis and plays a key role in carbohydrate and lipid metabolism [6,7,8].…”

Section: Introductionmentioning

confidence: 99%

Biochemical and histological indicators of blood and m. longissimus dorsi of young bulls of Kazakh white-headed breed of different genotypes by the CAPN1 and GH genes

Selionova

Plakhtyukova

2020

Teor. prakt. pererab. mâsa (Print)

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The use of molecular genetic markers for productivity is one of the modern approaches in breeding beef cattle. The article presents the results of the studies on the influence of genotypes by the calpain (CAPN1) and growth hormone (GH) genes on live weight, fatty acid composition of blood plasma, quantitative and qualitative indicators of meat of young cattle of Kazakh white-headed breed. It was established that animals of the homozygous geno-types СС–CAPN1 and VV-GH had a larger live weight and its average daily gain on the 240th and 365th days. Their superiority over the GG and LL genotypes was 13.8% (P<0.05) and 6.9%; 14.6% (P<0.05) and 6.9%, respectively. The carriers of the desirable alleles in the homozygous state had the sum of unsaturated fatty acids higher by 6.3% and 7.1%, respectively, than the young bulls, in which genotypes they were absent. The predominance of unsaturated fatty acids over saturated fatty acids also determined lower values of lipid me-tabolism direction index (0.92 and 1.00) in the animals with the desirable genotype. Muscle tissue of animals of the СС and VV genotypes was characterized by a higher level of protein, fat by 0.28–2.13 abs. per cent, energy value, and the quantity of muscle fibers with a smaller diameter per unit area compared to the GG and LL genotypes by on average 8.7% and 25.5% (P<0.01). Due to the greater number of interfiber fat inclusions, muscle tissue of the desirable genotypes received higher marbling scores. The obtained data testify to the prospects of replication of animals, which genotype has the desirable alleles for further improvement of traits of meat productivity of Kazakh white-headed breed.

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Polymorphism of somatotropin, prolactin, leptin, and thyreoglobulin genes in bulls

Cited by 12 publications

References 5 publications

Effect of the bovine TG5 gene polymorphism on milk- and meat-producing ability

Effect of the bovine TG5 gene polymorphism on milk- and meat-producing ability

Evaluation towards stud bulls with different mixed genotypes relating to somatotropin cascade genes by origin

Biochemical and histological indicators of blood and m. longissimus dorsi of young bulls of Kazakh white-headed breed of different genotypes by the CAPN1 and GH genes

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