Polymorphisms of miR-196a2 (rs11614913) and miR-605 (rs2043556) confer susceptibility to gastric cancer

Upregulation of the APE1 and H2AX genes and miRNAs involved in DNA damage response and repair in gastric cancer

“…These results are interesting and should be confirmed in future studies. Moreover, a previous study from our laboratory showed that the miR-605 rs2043556 (A > G) polymorphism confers an increased risk for the development of gastric cancer in individuals from the southeastern region of Brazil, 59 thus indicating a possible involvement of this miRNA in gastric carcinogenesis.…”

A Meta-Analysis of miR-499 rs3746444 Polymorphism for Cancer Risk of Different Systems: Evidence From 65 Case-Control Studies

“…Of the 65 studies, sample sizes ranged from 175 to 3,585, and publication year ranged from 2009 to 2017. In total, there were 2 acute lymphoblastic leukemia studies (Gutierrez-Camino et al, 2014 ; Hasani et al, 2014 ), 10 breast cancer studies (Hu et al, 2009 ; Catucci et al, 2010 ; Alshatwi et al, 2012 ; Bansal et al, 2014 ; Omrani et al, 2014 ; He et al, 2015 ; Qi et al, 2015 ; Dai et al, 2016 ; Afsharzadeh et al, 2017 ), 3 bladder cancer studies (Mittal et al, 2011 ; Deng et al, 2015 ; Wang et al, 2016 ), 5 colorectal cancer studies (Min et al, 2012 ; Vinci et al, 2013 ; Hu et al, 2014 ; Dikaiakos et al, 2015 ; Ying et al, 2016 ), 2 cervical squamous cell carcinoma studies (Zhou et al, 2011 ; Srivastava et al, 2017 ), 3 esophageal cancer studies (Umar et al, 2013 ; Wei et al, 2013 ; Shen et al, 2016 ), 7 gastric cancer studies (Okubo et al, 2010 ; Ahn et al, 2013 ; Wu et al, 2013 ; Pu et al, 2014 ; Cai et al, 2015 ; Poltronieri-Oliveira et al, 2017 ; Rogoveanu et al, 2017 ), 17 hepatocellular carcinoma studies (Akkiz et al, 2011 ; Kim et al, 2012 ; Xiang et al, 2012 ; Zhou et al, 2012 , 2014 ; Shan et al, 2013 ; Zou and Zhao, 2013 ; Chu et al, 2014 ; Hao et al, 2014 ; Kou et al, 2014 ; Ma et al, 2014 ; Qi et al, 2014 ; Wang et al, 2014 ; Li D. et al, 2015 ; Li X. et al, 2015 ; Yan et al, 2015 ; Zhang et al, 2016 ), 4 lung cancer studies (Tian et al, 2009 ; Vinci et al, 2011 ; Li D. et al, 2016 ), 2 oral squamous cell cancer studies (Hou et al, …”

The correlation ofmicroRNA-499rs3746444 T>C locus with the susceptibility of gastric cancer: from a case–control study to a meta-analysis

“…With an additional filter, twenty-two articles were excluded (ten were reviews and meta-analyses, four were designed as not case-control study, three were uncorrelated to the relationship of rs3746444 with GC risk, three focused on the prognosis, one was repetitive data and one was Erratum). Finally, after a detailed filtrate, nine literatures and the current case-control study involving twelve independent studies were included [14][15][16][17][18][19][20][21][22]. In total, we recruited 3954 GC cases and 9745 controls.…”

“…These contained publications were performed in Asians [14,15,[17][18][19][20] and Caucasians [16,21,22]. Three independent studies were conducted in GCA [15,16], seven were in non-GCA [14,16,[18][19][20]22], and two were in mixed [17,21]. Other detailed information was presented in Tables 4 and 5.…”

“…Most of these findings suggested that rs3746444 C-allele carriers appeared to get an increased susceptibility of cancer [8][9][10]12,13]. The relationship between rs3746444 SNP and GC susceptibility has also been investigated [14][15][16][17][18][19][20][21][22]. However, the correlation of rs3746444 polymorphism with GC development was still unconfirmed.…”