Polymorphous low-grade adenocarcinoma of the tonsil: Report of a case and review of the literature

Pittman, Cory B.; Zitsch, Robert P.

doi:10.1053/ajot.2002.124194

Cited by 17 publications

(8 citation statements)

References 9 publications

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“…Adenocarcinomas account for less than 1% of all malignancies of the palatine tonsils [ 3 ], with only a few studies having described the presence of such tumors at this site. The most frequent histological subtypes are represented by adenoid cystic carcinoma [ 13 , 14 ] and polymorphous low-grade adenocarcinoma [ 12 ]. Regarding MEC, only two cases arising in the palatine tonsils have been described in the literature [ 29 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

“…Interestingly, despite the presence of minor salivary glands in the palatine tonsils, the development of malignant salivary tumors here is unusual. Indeed, a scarce number of case reports have been documented in the scientific literature [ 12 – 14 ]. The present paper, therefore, aimed to report a case of MEC arising in the palatine tonsil.…”

Section: Introductionmentioning

confidence: 99%

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Mucoepidermoid Carcinoma of the Palatine Tonsil

Teixeira

Montalli

Teixeira

et al. 2015

Case Reports in Oncological Medicine

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Mucoepidermoid carcinoma (MEC) is the most common primary salivary gland malignancy in both adults and children. It has a slight female predilection and usually presents as a painless, rubber-like or soft mass, which may be fixed or mobile. Histologically, MEC is comprised of a mixture of cell types including mucous, epidermoid, and intermediate cells that can be arranged in solid nests or cystic structures. In the oral cavity, it most frequently occurs at the palate or buccal mucosa. The present paper aimed to describe an unusual case of MEC arising in the palatine tonsil.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Mucoepidermoid Carcinoma of the Palatine Tonsil

Teixeira

Montalli

Teixeira

et al. 2015

Case Reports in Oncological Medicine

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“…Polymorphous low-grade adenocarcinoma of minor salivary glands of the oral cavity [5,9] has been recently described in the sinonasal tract [12,15,20]. Polymorphous low-grade adenocarcinoma is characterised by histological blandness and cytological uniformity, but it differs from sinonasal tubulopapillary low-grade adenocarcinoma by its considerable morphological variability and frequent perineural invasion.…”

Section: Discussionmentioning

confidence: 99%

Sinonasal tubulopapillary low-grade adenocarcinoma. Histopathological, immunohistochemical and ultrastructural features of poorly recognised entity

et al. 2003

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We present the clinicopathological, histological and immunohistochemical findings of six cases of primary tubulopapillary low-grade adenocarcinoma of the sinonasal tract with ultrastructural examination in one case. Due to its unique features, we believe that primary tubulopapillary low-grade adenocarcinoma of the sinonasal tract represents a tumour entity different from any tumours generally recognised in the sinonasal region. Our cases had an equal sex incidence, with an age range of 44-76 years. The tumour has a tendency to recur, but none of our six patients developed metastases. We feel that it is important to separate this tumour entity from other types of sinonasal adenocarcinomas that exhibit a papillary growth pattern, as they frequently pursue a much more aggressive clinical course than the tumours in this study.

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“…Polymorphous low-grade adenocarcinoma does not have a tendency to be multifocal, but the odd cases of simultaneous multifocal intraoral PLGA have been described [ 18 ]. On rare occasions, PLGA have been reported in the nasopharynx [ 39 , 121 , 122 ], maxillary sinus [ 14 , 30 ], tongue [ 24 , 45 , 59 ], tonsil [ 88 ], vulva and vagina [ 126 ] and the lung and bronchus [ 11 , 15 , 62 ]. Only four cases of intraosseous PLGA appear to have been reported, two in the mandible [ 25 , 92 ] and possibly two in the maxilla [ 40 , 98 ].…”

Section: Defi Nition Site and Incidencementioning

confidence: 99%