Polyostotic Fibrous Dysplasia on F-18 FDG PET/CT Imaging

D’Souza, Maria; Jaimini, Abhinav; Khurana, Aditi; Tripathi, Madhavi; Sharma, Rajnish; Mondal, Anupam; Srivastava, Madhur Kumar

doi:10.1097/rlu.0b013e3181a34648

Cited by 7 publications

(3 citation statements)

References 7 publications

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“…The utility of volume rendering has also been demonstrated in evaluation of the bony deformities. [6] The “pirate sign” has been previously described on planar bone scintigraphy in FD. [7] Recent studies have described the advantage of performing bone SPECT in addition to CT to determine the extent of FD in the skull base and of hybrid SPECT/CT imaging in FD of the lumbar vertebra.…”

Section: Discussionmentioning

confidence: 99%

An interesting case of polyostotic fibrous dysplasia: The "pirate sign" evaluated with Tc-99m methylene diphosphonate single-photon emission computed tomography/computerized tomography

et al. 2011

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Section: Discussionmentioning

confidence: 99%

An interesting case of polyostotic fibrous dysplasia: The "pirate sign" evaluated with Tc-99m methylene diphosphonate single-photon emission computed tomography/computerized tomography

et al. 2011

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“…Bone FD lesions may present 18 F-FDG-negative (109,110) or exhibit variable degrees of 18 F-FDG activity on PET/CT, mimicking malignancy (111)(112)(113)(114)(115)(116). However, co-registration with CT enables confident characterization of lesions and avoidance of erroneous interpretation of 18 F-FDG positive skeletal findings.…”

Section: Fibrous Dysplasiamentioning

confidence: 99%

PET/CT and PET/MRI in ophthalmic oncology (Review)

et al. 2020

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Orbital and ocular anatomy is quite complex, consisting of several tissues, which can give rise to both benign and malignant tumors, while several primary neoplasms can metastasize to the orbital and ocular space. Early detection, accurate staging and re-staging, efficient monitoring of treat-ment response, non-invasive differentiation between benign and malignant lesions, and accurate planning of external radiation treatment, are of utmost importance for the optimal and individualized management of ophthalmic oncology patients. Addressing these challenges requires the employment of several diagnostic imaging techniques, such as high-definition digital fundus photography, ultrasound imaging, optical coherence tomography, optical coherence tomography (OCT)-angiography, computed tomography (CT) and magnetic resonance imaging (MRI). In recent years, technological advances have enabled the development of hybrid positron emission tomography (PET)/CT and PET/MRI systems, setting new standards in cancer diagnosis and treatment. The capability of simultaneously targeting several cancer-related biochemical procedures using positron emitting-radiopharmaceuticals, while morphologically characterizing lesions by CT or MRI, together with the intrinsic quantitative capabilities of PET-imaging, provide incremental diagnostic information, enabling accurate, highly efficient and personalized treatment strategies. Aim of the current review is to discuss the current applications of hybrid PET/CT and PET/MRI imaging in the management of patients presenting with the most commonly encountered orbital and ocular tumors.

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“…They may be mildly expansile and there can be varying degrees of hazy internal density with a ground-glass appearance (Fig 13) (74). In the setting of polyostotic fibrous dysplasia, FDG PET/CT has notable advantages over other imaging modalities in that it can help the physician establish the extent of bone involvement, characterize each lesion (Fig 13), and assess for any potential complications such as pathologic fracture, or, rarely, sarcomatous degeneration (75). Fibrous dysplasia can range from intensely hypermetabolic to non-FDG-avid, and there can be varying degrees of FDG uptake within different regions of a single lesion or in different lesions in the same individual.…”

Section: Fibrous Dysplasiamentioning

confidence: 99%

Spectrum of Benign Articular and Periarticular Findings at FDG PET/CT

White¹,

Johnson²,

Howe³

et al. 2016

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Whole-body fluorine 18 fluorodeoxyglucose (FDG) positron-emission tomography (PET)/computed tomography (CT) is performed primarily for oncologic indications; however, FDG uptake is not specific for malignancy. Herein we focus on causes of increased FDG uptake in and around joints, as lesions in these locations are commonly benign. A combination of primary intra-articular processes and osseous processes that may occur near the joint space will be discussed. Causes of intra-articular and periarticular increased FDG activity can be broadly divided into infectious, inflammatory, degenerative, and benign neoplastic categories. A familiarity with the full range of these processes is important to avoid misinterpretation, in turn decreasing unnecessary follow-up studies, procedures, and treatments. Differentiation from malignancy is often possible on the basis of a different level of FDG activity, divergent response to therapy, or differing changes over time, in comparison with a patient's known primary cancer. Recognizing an intra-articular lesion location can also be critical, as intra-articular metastases are rare. In some cases, benign FDG-avid articular and periarticular entities have a specific appearance at FDG PET/CT and a correct diagnosis may be made without any additional workup. In most other cases, comparison with prior studies and/or additional imaging can afford an accurate diagnosis. This review is meant to introduce the reader to a spectrum of benign FDG-avid articular and periarticular processes that may be encountered at oncologic FDG PET/CT to increase confidence and diagnostic accuracy. (©)RSNA, 2016.

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Polyostotic Fibrous Dysplasia on F-18 FDG PET/CT Imaging

Cited by 7 publications

References 7 publications

An interesting case of polyostotic fibrous dysplasia: The "pirate sign" evaluated with Tc-99m methylene diphosphonate single-photon emission computed tomography/computerized tomography

An interesting case of polyostotic fibrous dysplasia: The "pirate sign" evaluated with Tc-99m methylene diphosphonate single-photon emission computed tomography/computerized tomography

PET/CT and PET/MRI in ophthalmic oncology (Review)

Spectrum of Benign Articular and Periarticular Findings at FDG PET/CT

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