2023
DOI: 10.3390/brainsci13121709
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Polypathologies and Animal Models of Traumatic Brain Injury

Erin Freeman-Jones,
William H. Miller,
Lorraine M. Work
et al.

Abstract: Traumatic brain injury (TBI) is an important health issue for the worldwide population, as it causes long-term pathological consequences for a diverse group of individuals. We are yet to fully elucidate the significance of TBI polypathologies, such as neuroinflammation and tau hyperphosphorylation, and their contribution to the development of chronic traumatic encephalopathy (CTE) and other neurological conditions. To advance our understanding of TBI, it is necessary to replicate TBI in preclinical models. Com… Show more

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