Polypharmacy and drug-drug interactions among older and younger male prisoners in Switzerland

Annaheim, Beatrice; Wangmo, Tenzin; Handtke, Violet; Elger, Bernice Simone; Meyer, Andrea; Hösli, Raphael; Lutters, Monika

doi:10.1108/ijph-07-2018-0040

Cited by 3 publications

(1 citation statement)

References 37 publications

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“…11 Older prisoners take more medications than younger prisoners and are at increased risk for polypharmacy, defined as 5 medications a day. 12 Older prisoners have mental health disorders more frequently than younger prisoners and also abuse alcohol more frequently. 13 Finally, older female prisoners have a different set of concerns.…”

Section: Demographics and Comorbiditiesmentioning

confidence: 99%

The evolution of health care in the Texas correctional system and the impact of COVID-19

Rao

Ali

Berdine

et al. 2020

Baylor University Medical Center Proceedings

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Health care under the jurisdiction of the Texas Department of Criminal Justice has evolved over time to provide prisoners greater access to medical care, including psychiatric care and substance abuse assistance. Mental illness and chronic conditions, such as hypertension, chronic obstructive pulmonary disease, diabetes, and heart disease, are common in prisoners in Texas and across the nation and increase the cost of health care. The average annual health care cost per prisoner in Texas was $4077 in 2015. Although the Texas prison system has undergone changes, such as the use of telemedicine and protocols for preventive measures, to address the varying medical needs of prisoners in correctional facilities, there is still considerable criticism regarding prison policies and incomplete access to medical care. In addition, the ongoing COVID-19 pandemic has added significant stress to correctional health care in Texas and highlights the importance of organized health care for prisoners. This report reviews the history and evolution of health care delivery in Texas's correctional facilities, outlines ongoing efforts to improve medical care in prison facilities, and describes current policies to limit COVID-19 infections in Texas prisons.

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Section: Demographics and Comorbiditiesmentioning

confidence: 99%

The evolution of health care in the Texas correctional system and the impact of COVID-19

Rao

Ali

Berdine

et al. 2020

Baylor University Medical Center Proceedings

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Potential drug-drug interactions in ICU patients: a retrospective study

Ali

Bazzar

Hussein

et al. 2020

Drug Metabolism and Drug Interactions

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ObjectivesA “potential drug-drug interaction” (pDDI) is the possibility one drug has to alter the effects of another when both are administered simultaneously. Intensive care unit (ICU) patients are especially prone to these pDDIs. This study aimed to determine the frequency and severity of pDDIs during the hospitalization of patients in the ICU.MethodsThis study was conducted retrospectively in three hospitals, including both governmental and non-governmental hospitals in Nablus, Palestine, over the course of six months; starting in January 2018 and ending in June 2018. The sample size included 232 ICU patients, and medications prescribed during the hospitalization of these patients were evaluated for pDDIs using the drugs.com application.ResultsA total of 167 patients (72%) were found to have at least one pDDI, while the total number of pDDIs in the study was 422, resulting in an average of 1.82 pDDIs per patient. Out of the total identified pDDIs, 41 interactions (9.7%) were major interactions, 281 (66.6%) were moderate interactions and 100 (23.7%) were minor interactions. The past medical history of these patients showed that many had hypertension (29%), diabetes mellitus (25%) and ischemic heart disease (10%). A serious combination, enoxaparin and aspirin, was found in six patients. Furthermore, as the number of administered drugs increased, the number of interactions increased as well.ConclusionsThe pDDIs are common in ICU patients. The most common and clinically most important pDDIs require special attention. Polypharmacy significantly increases the number and level of pDDIs, especially in patients with multiple chronic illnesses. Adequate knowledge regarding the most common pDDIs is necessary to enable healthcare professionals to implement ICU strategies that ensure patient safety.

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Real-world Effectiveness of sofosbuvir/velpatasvir for the Treatment of Hepatitis C Virus in Prison Settings

et al. 2022

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Background: People in prison are at high risk of hepatitis C virus (HCV) infection and often have a history of injection drug use and mental health disorders. Simple test-and-treat regimens which require minimal monitoring are critical. Methods: This integrated real-world analysis evaluated the effectiveness of once daily sofosbuvir/velpatasvir (SOF/VEL) in 20 prison cohorts across Europe and Canada. The primary outcome was sustained virological response (SVR) in the effectiveness population (EP), defined as patients with a valid SVR status. Secondary outcomes were reasons for not achieving SVR, adherence and time between HCV RNA diagnosis and SOF/VEL treatment. Results: Overall, 526 people in prison were included with 98.9% SVR achieved in the EP (n = 442). Cure rates were not compromised by drug use or existence of mental health disorders. Conclusion: SOF/VEL for 12 weeks is highly successful in prison settings and enables the implementation of a simple treatment algorithm in line with guideline recommendations and test-and-treat strategies.

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Polypharmacy and drug-drug interactions among older and younger male prisoners in Switzerland

Cited by 3 publications

References 37 publications

The evolution of health care in the Texas correctional system and the impact of COVID-19

The evolution of health care in the Texas correctional system and the impact of COVID-19

Potential drug-drug interactions in ICU patients: a retrospective study

Real-world Effectiveness of sofosbuvir/velpatasvir for the Treatment of Hepatitis C Virus in Prison Settings

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