Polypharmacy as a risk factor for adverse drug reactions in geriatric nursing home residents

Nguyen, Julia K.; Fouts, Michelle; Kotabe, Sharon; Lo, Y. T. Eunice

doi:10.1016/j.amjopharm.2006.03.002

Cited by 242 publications

(177 citation statements)

References 18 publications

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“…The incidence of 10.6% ADRs found in this study is low as compared to other general or outpatient studies conducted in different countries [8,9,18]. This could be due to the difference in the methodological aspects of the study particularly the study population and the self-reporting of ADRs in the follow-ups which was conducted through telephonic calls in the current study.…”

Section: Discussioncontrasting

confidence: 42%

“…Nguyen's findings [9], we performed a hospital based prospective cohort study where we surveyed the geriatric population (.65 years) attending the outpatient clinics of Aga Khan University Hospital Karachi throughout the year 2012. The data was collected from different consulting clinics of Anesthesia, Family Medicine, Internal Medicine and Obstetrics.…”

Section: Research In Contextmentioning

confidence: 99%

“…Few epidemiological studies investigating the role of polypharmacy among the geriatrics have been almost exclusively conducted in the developed countries [9,10]. However, there is a scarcity of evidence from Asian countries including Pakistan, and prospective studies investigating the association between polypharmacy and ADRs are almost lacking [11,12].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of Polypharmacy on Adverse Drug Reactions among Geriatric outpatients at a Tertiary Care Hospital in Karachi, A prospective cohort study.

Ahmed

Nanji

Patel

2015

International Journal of Epidemiology

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Background: Adverse drug reactions (ADRs) present a challenging and expensive public health problem. Polypharmacy is defined according to the WHO criteria as the, ''concurrent use of five or more different prescription medication''. Elderly are more prone to adverse reactions due to comorbid conditions, longer lists of medications and sensitivity to drug effects. The aim of the study is to estimate the incidence and strength of association of ADRs due to polypharmacy among the geriatric cohort attending outpatient clinics at a tertiary care center.

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Section: Discussioncontrasting

confidence: 42%

Section: Research In Contextmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of Polypharmacy on Adverse Drug Reactions among Geriatric outpatients at a Tertiary Care Hospital in Karachi, A prospective cohort study.

Ahmed

Nanji

Patel

2015

International Journal of Epidemiology

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“…Polypharmacy is an established risk factor for ADRs and there is evidence that increasing number of drugs causes increased incidence of ADRs [16] . ADRs due to drug-drug interactions are a common cause of admission to the hospital and are an important cause of mortality and morbidity.…”

Section: Resultsmentioning

confidence: 99%

Patterns, Predictors and Outcomes of Polypharmacy among Elderly Perioperative Patients in the General Surgical Department of a Tertiary Care Teaching Hospital

Saldanha¹,

Raj²,

Devi³

et al. 2017

pharmaceutical-sciences

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“…Drug side effects have been found to be more frequent among those living in nursing homes because they are in the geriatric age group and the people living in the nursing homes use more drugs than those living in the community [7,8].…”

Section: Introductionmentioning

confidence: 99%

Polypharmacy and associated factors in people living in a nursing home in Kayseri Turkey

Göçer¹,

Günay²,

Polat³

et al. 2017

Med-Science

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It has been found that residents of nursing homes have more frequent drug side effects, because they use more drugs than those living in the community. This study was conducted to determine the status of polypharmacy and related factors among the individuals living in a nursing home. Materials and Methods: The cross-sectional study was conducted in a nursing home in the provincial centre of Kayseri in 2016. A socio-demographic questionnaire and Standardized Mini Mental Test (SMMT) were used for data collection. A total of 99 participants were included in the study. Chi square test, unpaired t test and one-way ANOVA test (Posthoc Scheffe test) were used for statistical analyses. Results: It was determined that, 58.6% of the study group was male, mean age was 76.0±9.5 years, and 88.9% used at least one kind of medicine. The prevalence rate of polypharmacy was found 59.6%. According to SMMT scores, 66.7% of the participants had cognitive impairment. Prevalence rate of polypharmacy was found 69.0% among the individuals with cognitive impairment. From the standpoint of polypharmacy, statistically significant differences were found between the participants having and not having chronic diseases, such as hypertension, diabetes, heart disease and chronic obstructive pulmonary disease. Conclusions: Polypharmacy was determined in more than half of the individuals living in nursing home. Individuals living in nursing homes should be informed about the use of medicines and their medicine use should be closely monitored.

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Polypharmacy as a risk factor for adverse drug reactions in geriatric nursing home residents

Cited by 242 publications

References 18 publications

Effects of Polypharmacy on Adverse Drug Reactions among Geriatric outpatients at a Tertiary Care Hospital in Karachi, A prospective cohort study.

Effects of Polypharmacy on Adverse Drug Reactions among Geriatric outpatients at a Tertiary Care Hospital in Karachi, A prospective cohort study.

Patterns, Predictors and Outcomes of Polypharmacy among Elderly Perioperative Patients in the General Surgical Department of a Tertiary Care Teaching Hospital

Polypharmacy and associated factors in people living in a nursing home in Kayseri Turkey

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