Polyphenols and antioxidant capacity of Bulgarian medicinal plants

Ivanova, Diana; Gerova, Daniela; Chervenkov, Trifon; Yankova, T.

doi:10.1016/j.jep.2004.08.033

Cited by 371 publications

(258 citation statements)

References 19 publications

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“…Of these, reducing power, metal chelation, free radical scavenging, lipid peroxidation and DNA damage protection activities are the most commonly used for the evaluation of the total antioxidant behavior of extracts (Amarowicz et al 2000;Chang et al 2002). Studies have shown that 70% ethanol extract of plant materials contain ethanol and water soluble bioactive compounds possessing antioxidant property (Kahkonen et al 1999;Ivanova et al 2005). Hence in this study, 70% ethanol was used for the extraction.IC 50 values were calculated.…”

Section: Resultsmentioning

confidence: 99%

In vitro free radical scavenging and DNA damage protective property of Coriandrum sativum L. leaves extract

Harsha

Anilakumar

2012

J Food Sci Technol

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Coriandrum sativum L. (coriander), an everyday spice in the Indian kitchen is known to add flavor to the cuisine. It is an annual herb belonging to the Apiaceae (Umbellifera) family. The hydro-alcohol extract of Coriandrum sativum L. at the dose of 1 mg/ml was subjected to a series of in vitro assays viz. 2, 2′-diphenyl-1-picrylhydrazyl, lipid peroxidation by thiobarbituric acid, reducing power and nitric oxide (NO) radical scavenging in order to study its antioxidant efficacy in detail. The amount of flavonoids in 70% ethanol extract was found to be 44.5 μg and that of the total phenols was 133.74 μg gallic acid equivalents per mg extract. The extracts of the leaves showed metal chelating power, with IC 50 values, 368.12 μg/ ml where as that of standard EDTA was 26.7 μg/ml. The IC 50 values for 2, 2′-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid radical scavenging was 222 μg/ml where as that of standard ascorbic acid was 22.6 μg/ml. The NO scavenging activity of the extract of the leaves showed IC 50 value of 815.6 μg/ml; at the same time the standard BHA had 49.1 μg/ml. All the plant extracts provided DNA damage protection; however, the protection provided at the dose of 8 μg/ml was comparable to that of standard gallic acid. The Coriandrum sativum leaf extract was able to prevent in vitro lipid peroxidation with IC 50 values; 589.6 μg/ml where as that of standard BHA was 16.3 μg/ml. Our results also showed significant ferric reducing power indicating the hydrogen donating ability of the extract. This study indicated the potential of the leaf extract as a source of natural antioxidants or nutraceuticals that could be of use in food industry with potential application to reduce oxidative stress in living system.

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Section: Resultsmentioning

confidence: 99%

In vitro free radical scavenging and DNA damage protective property of Coriandrum sativum L. leaves extract

Harsha

Anilakumar

2012

J Food Sci Technol

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“…The detailed information is summarized in Table 1. Many studies were dedicated to biological activity of rosehip fruits (Ognyanov et al, 2014, Taneva et al, 2016, thyme (Thymus vulgaris L.) and peppermint (Ivanova et al, 2005, Kolaneva et al, 2016. Common thyme is an aromatic plant that belongs to Lamiaceae family.…”

Section: Introductionmentioning

confidence: 99%

“…Herbal infusion of peppermint (Mentha piperita) leaves helps in curing indigestion, jaundice, liver diseases and gastric disorders. It was reported that the flavonoids and phenolic acids in Mentha piperita exhibited antioxidant, cholegogic and anti-allergic activities (Ivanova et al, 2005, Krachanova et al, 2010.…”

Section: Introductionmentioning

confidence: 99%

Antioxidants and carbohydrate content in infusions and microwave extracts from eight medicinal plants

2017

J App Pharm Sci

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The aims of the current research were to evaluate and to compare the antioxidant activity and the content of total phenolic, flavonoids and fructan content in infusions and microwave-assisted extracts from eight herbs:and echinacea (Echinacea purpurea Moench.). The total phenolic contents, total flavonoids and antioxidant activity were evaluated by Folin-Ciocalteau, Al(NO3)3 methods and DPPH assays. The total fructans and sugars were determined by resorcinol and HPLC-RID methods. Infusion and microwave-assisted extraction (MAE) were evaluated as efficient methods for preparation of herbal drinks. The highest values of biologically active substances and antioxidant activity were found in MAE herbal extracts. Coltsfoot, thyme and great burdock extracts demonstrated the highest content of total phenolic and flavonoids. Coltsfoot and thyme extracts showed the highest antioxidant activity (334 mM TEg -1 and 287 mM TEg -1 dw, respectively). Fructans were found in coltsfoot (4.6%) and echinacea (3.9 %) leaves, in great burdock, dandelion and elecampane roots -14 %, 34% and 44% dw, respectively. Elecampane and dandelion roots were evaluated as sources of prebiotic inulin.

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“…[11][12][13] That is why many research groups investigated the connection between the antioxidant capacity and polyphenol content of plants. [14][15][16][17] In most cases, the surveys have been related to traditionally used medicinal plants. [12,17] Polygonum glabrum willd.…”

Section: Introductionmentioning

confidence: 99%

“…[14][15][16][17] In most cases, the surveys have been related to traditionally used medicinal plants. [12,17] Polygonum glabrum willd. (Polygonaceae) commonly known as Attalaree in Tamil and Niru Kanigalu in Mangalore.…”

Section: Introductionmentioning

confidence: 99%

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Satyanarayana

2017

IJGP

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Aim: The present work carried out to evaluate of the phytochemicals present in the selected plants which are biologically active and in vitro anti-oxidant activity. Materials and Methods: Four selected plants Polygonum glabrum, Canthium dicoccum Ochna obtusata, Argyreia nervosa of Petroleum collected and plant material is dried according to the standard procedure. The dried plant materials powdered using blenders. The powdered material is subjected to extraction using different solvent systems and filtrate is collected. Finally the filtarate is dried crude used for further studies. Results and Discussion: Ether Extract, Ethyl Acetate Extract, and Aqueous Extracts revealed that presence of bioactive compound likes saponins, phyto-sterols and phenolic are in relatively in high concentration in preliminary phytochemical study. The quantitate estimation of phenolic compound carried out by using Folin-Ciocalteu method and flavonoid by colorimetric method using aluminum chloride to establish the relation between the antioxidant activity and phenolic and flavonoid content. The total phenol content and flavonoid content ethanol extracts are relatively more than other extracts with respect to the standard concentration of Gallic acid and rutin .In selected plants ethanol extract showed significant anti-oxidant activity of on dose dependent manner. In all the assays IC50 values are determined using ascorbic acid is a standard. Conclusion:The results obtained from the present investigation the selected four plants are having good bioactive compound hence the plants can be used as potential source of natural antioxidants and Pharmaceuticals.

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Polyphenols and antioxidant capacity of Bulgarian medicinal plants

Cited by 371 publications

References 19 publications

In vitro free radical scavenging and DNA damage protective property of Coriandrum sativum L. leaves extract

In vitro free radical scavenging and DNA damage protective property of Coriandrum sativum L. leaves extract

Antioxidants and carbohydrate content in infusions and microwave extracts from eight medicinal plants

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