Polyphenols in edible plant leaves: an overview of their occurrence and health properties

Masiala, Anthony; Vingadassalon, Audrey; Aurore, Guylène

doi:10.1039/d4fo00509k

Cited by 6 publications

(1 citation statement)

References 245 publications

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“…Antioxidant, anticancer, and neuroprotective activities have been observed in SA as a natural HCA . SA has also shown metal chelating potential, anti-inflammatory, antibacterial, antihyperglycemic, antimicrobial, anxiolytic, and tumor-fighting activities, peroxynitrite and free-radical scavenging, plus antihypertensive and cardiovascular remodeling , (Figure ). It is shown that SA’s poor solubility, hydrophobic nature, low in vitro dissolution rate, reduced oral bioavailability, and enhanced lipophilicity due to the esterification are responsible for its limited therapeutic potential whereas the increased lipophilicity results in higher affinity for the lipophilic phase of certain drug delivery systems and the cell membrane. − In this regard, several studies have been performed to investigate the possible strategies for a more effective delivery of SA for therapeutic purposes.…”

Section: Chemical Propertiesmentioning

confidence: 99%

Pharmacological Activities and Molecular Mechanisms of Sinapic Acid in Neurological Disorders

Farzan,

Abedi,

Bhia

et al. 2024

ACS Chem. Neurosci.

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Sinapic acid (SA) is a phenylpropanoid derivative found in various natural sources that exhibits remarkable versatile properties, including antioxidant, anti-inflammatory, and metalchelating capabilities, establishing itself as a promising candidate for the prevention and treatment of conditions affecting the central nervous system, such as Alzheimer's disease (AD), Parkinson's disease (PD), ischemic stroke, and other neurological disorders. These effects also include neuroprotection in epilepsy models, as evidenced by a reduction in seizure-like behavior, cell death in specific hippocampal regions, and lowered neuroinflammatory markers. In AD, SA treatment enhances memory, reverses cognitive deficits, and attenuates astrocyte activation. SA also has positive effects on cognition by improving memory and lowering oxidative stress. This is shown by lower levels of oxidative stress markers, higher levels of antioxidant enzyme activity, and better memory retention. Additionally, in ischemic stroke and PD models, SA provides microglial protection and exerts anti-inflammatory effects. This review emphasizes SA's multifaceted neuroprotective properties and its potential role in the prevention and treatment of various brain disorders. Despite the need for further research to fully understand its mechanisms of action and clinical applicability, SA stands out as a valuable bioactive compound in the ongoing quest to combat neurodegenerative diseases and enhance the quality of life for affected individuals.

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Section: Chemical Propertiesmentioning

confidence: 99%

Pharmacological Activities and Molecular Mechanisms of Sinapic Acid in Neurological Disorders

Farzan,

Abedi,

Bhia

et al. 2024

ACS Chem. Neurosci.

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Fermented Feed in Broiler Diets Reduces the Antinutritional Factors, Improves Productive Performances and Modulates Gut Microbiome—A Review

Predescu,

Stefan,

Rosu

et al. 2024

Agriculture

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The aim of this review is to highlight the most beneficial effects of dietary fermented feed in correlation with decreasing the antinutrient concentration in vegetal matrices usually used for broiler nutrition. Rational feed formulation is critical for animals because it improves animal performance, and provides the animal with the necessary nutrients to develop strong bones, muscles and tissues, and a properly functioning immune system. Fermentation of animal feed is useful as compounds with high molecular mass are converted into energy and compounds with lower molecular mass in the presence of enzymes produced mainly by bacteria and yeasts. Fermentation products contain probiotic compounds with beneficial effects on the health of the animal microbiome. Feed fermentation has other roles such as converting antinutrients into beneficial substances for animal organisms, and some studies have shown that fermentation of feed decreases the risk of antinutrient components presence. For the bibliographic research, different platforms were used (PubMed, Science Direct, MDPI resources), and numerous words or combinations of terms were used to find the latest information. Fermented feed utilization has been shown to enhance growth performance while promoting a healthier gut microbiome in animals.

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Terminalia catappa Kernel Flour Characterization as a Functional and Bioactive Ingredient for Cookies Formulation

Vingadassalon,

Pejcz,

Wojciechowicz-Budzisz

et al. 2024

Applied Sciences

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Terminalia catappa (tropical almond) represents an underutilized resource with potential applications in functional food development. This study investigated the technological properties and bioactive characteristics of T. catappa kernel flour and its application in cookie formulation. The research examined the techno-functional properties, pasting behavior, and bioactive profile of T. catappa flour and its blends with different sweeteners (erythritol and cane sugar at 5% and 15% concentrations). Cookies were formulated using optimized ingredients, and their quality parameters were evaluated through physical, chemical, and sensory analyses. T. catappa flour demonstrated significant water holding capacity (4.48 g H2O/g DM) and notable antioxidant activity in both aqueous and ethanolic extracts (DPPH: 1.95–3.35 mg TE/g DM). The addition of sweeteners influenced pasting properties, with higher concentrations generally reducing peak viscosity and pasting temperature. Developed cookies exhibited stable water activity (0.294–0.320) over one month of storage and contained substantial dietary fiber (5.018 g/100 g). Sensory evaluation revealed superior acceptability for thicker (10 mm) cookies, particularly in texture and appearance attributes. This study establishes T. catappa kernel flour as a promising functional ingredient for gluten-free bakery applications, offering both technological functionality and bioactive properties suitable for health-conscious product development.

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Polyphenols in edible plant leaves: an overview of their occurrence and health properties

Abstract: Edible plant leaves (EPLs) constitute a major renewable functional plant biomass available all year round, providing an essential source of polyphenols in the global diet. Polyphenols form a large family...

Cited by 6 publications

References 245 publications

Pharmacological Activities and Molecular Mechanisms of Sinapic Acid in Neurological Disorders

Pharmacological Activities and Molecular Mechanisms of Sinapic Acid in Neurological Disorders

Fermented Feed in Broiler Diets Reduces the Antinutritional Factors, Improves Productive Performances and Modulates Gut Microbiome—A Review

Terminalia catappa Kernel Flour Characterization as a Functional and Bioactive Ingredient for Cookies Formulation

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