Polyphenols in the Prevention of Ulcerative Colitis

Baliga, Manjeshwar Shrinath; Saxena, Arpit; Kaur, Kirandeep; Kalekhan, Faizan; Chacko, Amala; Venkatesh, Ponemone; Fayad, Raja

doi:10.1016/b978-0-12-398456-2.00050-5

Cited by 22 publications

(19 citation statements)

References 49 publications

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“…Kaempferol has a wide variety of pharmacological activities including antioxidant, anti-inflammatory, antimicrobial, anticancer, cardioprotective, neuroprotective, antidiabetic, anti-osteoporotic, estrogenic/antiestrogenic, anxiolytic, analgesic, and antiallergic activities [75]. In fact, many studies demonstrated the beneficial effects of dietary kaempferol in reducing the risk of chronic diseases by augmenting the body's antioxidant defense against free radicals, which reinforces body immunity [73].…”

Section: Kaempferolmentioning

confidence: 99%

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

Khalil

Tazeddinova

2020

Nat. Prod. Bioprospect.

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Polyphenols are a large family of more than 10,000 naturally occurring compounds, which exert countless pharmacological, biological and physiological benefits for human health including several chronic diseases such as cancer, diabetes, cardiovascular, and neurological diseases. Their role in traditional medicine, such as the use of a wide range of remedial herbs (thyme, oregano, rosemary, sage, mint, basil), has been well and long known for treating common respiratory problems and cold infections. This review reports on the most highlighted polyphenolic compounds present in up to date literature and their specific antiviral perceptive properties that might enhance the body immunity facing COVID-19, and other viral infectious diseases. In fact, several studies and clinical trials increasingly proved the role of polyphenols in controlling numerous human pathogens including SARS and MERS, which are quite similar to COVID-19 through the enhancement of host immune response against viral infections by different biological mechanisms. Thus, polyphenols ought to be considered as a potential and valuable source for designing new drugs that could be used effectively in the combat against COVID‐19 and other rigorous diseases.

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Section: Kaempferolmentioning

confidence: 99%

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

Khalil

Tazeddinova

2020

Nat. Prod. Bioprospect.

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“…'Peschici' and 'Monteleone' appreciably highlighted a high amount of rutoside-1, known as rutin (a flavonol glycoside between quercetin and disaccharide rutinose), which has been found to have important pharmacological effects, such as in the prevention of ulcerative colitis [58]. Both 'Peschici' and 'Monteleone' also showed the highest amounts of iso-quercitrin (also named quercetin 3-β-D-glucoside), even if identified at low concentrations, this quercetin glucoside, which can be isolated from several Allium spp.…”

Section: Phenolic Compoundsmentioning

confidence: 99%

Evaluation of Garlic Landraces from Foggia Province (Puglia Region; Italy)

Bonasia

Conversa

Lazzizera

et al. 2020

Foods

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Interest in local landraces has unfortunately decreased over, the last decades, in which they have been continuously subjected to a high genetic erosion in favour of new modern varieties. Within the Puglia region (S-E Italy), Foggia province was found to be the richest in vegetable landraces. In the present study, six garlic landraces collected from this area have been assessed for their chemical composition (minerals, organic acids, free sugars, volatile, and phenolic compounds) along with their main morpho-biometrical traits. A commercial genotype was also considered as a reference standard. The landraces show a large variability, but in general high morphological standards, high levels of cations and phenols, and low levels of volatile-(S)-compounds in comparison with the commercial genotype and the literature values. ‘Aglio di Peschici’ and ‘Aglio Rosso di Monteleone di Puglia’ are very rich in minerals and phenols (mainly ferulic acid and iso-rhamnetin). This increase in knowledge on the chemical properties of these garlic landraces could represent a tool for encouraging the consumption of a food product. At the same time, the consumption of these landraces would stimulate their cultivation and could highly contribute to protection against the risk of erosion of agro-biodiversity by their in situ/on-farm conservation.

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“…The biochemical constituent that makes it therapeutically benefi cial are ellagic acid, ellagatannins, (including punicalin and punicalagin) punica acid, fl avonoids, anthocyanins, estrogenic fl avonols, fl avonols and fl avones. [9] There are many reports The results obtained in the present study showed pomegranate aril extract have signifi cantly higher inhibitory eff ect against Streptococcus in both dental caries patients and healthy individuals. The percentage of reduction was higher in experimental (52.2%) than control (33.8%).…”

Section: Discussionmentioning

confidence: 50%

“…[7] Pomegranate juice contains polyphenols, tannins ellagic acid, and anthocyanin which are powerful antioxidants. [1,2,6,8,9] Thus, the red arils (anthocyanin) having antioxidant property has a higher bioactivity compared to its purifi ed polyphenols. [1] As a result, pomegranate juice has become popular worldwide.…”

Section: Introductionmentioning

confidence: 99%

Anti-microbial activity of Punica granatum on streptococcus in dental caries patients and healthy individuals: A comparative study

Lalwani¹,

Koneru²,

Vanishree³

et al. 2014

JCRI

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Background: Researchers today are driven toward the medicinal and therapeutic value of the natural products like Aloe vera, basil, turmeric, green tea, pomegranate (Punica granatum) to prevent dental caries. The aim of the present study was to determine the antimicrobial activity of pomegranate aril extract on streptococci in dental caries patients and healthy individuals. Materials and Methods:The study group included 40 subjects; age comprised of 18-26 years 20 dental caries patients were taken as an experimental group (after observing the decayed missing fi lled teeth index) and 20 healthy individuals without caries as a control group. Two samples were collected from each subject. The collected sample was streaked on Mitis Salivarius Agar, which was incubated at 37°C for 24 h. The colony forming units (CFU) were counted using manual colony counter, and the data were analyzed using paired t-test and unpaired t-test. Results:The results obtained after pomegranate swish in the experimental group showed a percentage reduction of 52.2% (P < 0.0001) and 33.8% (P < 0.0001) in control group for the CFU. The comparison of after sample between the experimental group and the control group was highly signifi cant. Conclusion:The result obtained in the study clearly demonstrates that the pomegranate aril extract has an antimicrobial eff ect against Streptococcus, thus acting as an anti-cariogenic agent.

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Polyphenols in the Prevention of Ulcerative Colitis

Cited by 22 publications

References 49 publications

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

Evaluation of Garlic Landraces from Foggia Province (Puglia Region; Italy)

Anti-microbial activity of Punica granatum on streptococcus in dental caries patients and healthy individuals: A comparative study

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