“…[50][51][52][53][54][55] Finally, disaccharides themselves play an essential biological and technological role in terms of, for example, polysaccharide biosynthesis and degradation, energy storage and interconversion, bioprotection phenomena, and industrial food processing. 56,57 In a previous study 58,59 (Pereira et al, 2006), we reported the results of explicit-solvent molecular dynamics (MD) simulations investigating the conformational properties of the eight reducing disaccharides of D-glucopyranose (Fig. 1) in water on the 50 ns timescale using the GROMOS 45A4 force-field.…”