Polysaccharide hydrogel films/membranes for transdermal delivery of therapeutics

Nanoarchitectonics beyond perfect order – not quite perfect but quite useful

“…Numerous accounts in the literature have reported that self-assembled natural hydrogel films were multifunctional for a various range of biomedical applications over the decades. 218–221 For instance, Cui and co-workers designed smart hydrogel actuators constructed from chitosan and sodium alginate for assessing biomedical applications. 222 The gradient chitosan/sodium alginate complex hydrogel film, which is nano-porous, ultra-strong, and has adjustable thickness, provides practical guidance for application in drug delivery, tissue engineering, soft robotics, and active implants.…”

Recent advances and challenges on chitosan-based nanostructures by polyelectrolyte complexation and ionic gelation for anthocyanins stabilization

“…Besides composing a large part of the extracellular matrix of various connective tissues such as skin, bone, cartilage, ligaments, and tendons, CHS is involved in several biochemical activities such as antioxidants, anticoagulants, and antiinflammatory. (Kumari, & Badwaik, 2019;Shariatinia, & Barzegari, 2019). This natural polysaccharide has also been the subject of much research in the field of nanotechnology, including the formation of nanostructured systems with chitosan.…”

Prospects of kefiran as a food-derived biopolymer for agri-food and biomedical applications

“…Furthermore, keran can be conjugated or coupled with different biomacromolecules, proteins, peptides, and amino acids to develop bio-complex with favourable biochemical and biophysical properties compared to synthetic polymers. 118 This is attributed to its varying degree of structural branching that allows for cross-linking with other biomaterials to create novel materials. 68,119 Therefore, this aspect is an essential research endeavour for future work to investigate the cross-linking ability of keran to expand its potential to myriad of applications.…”