“…Most natural polysaccharides (e.g., chitosan, starch, alginate) contain hydrophilic groups (hydroxyl, carboxyl, amino), which show bioadhesion to biological structures (epithelia, mucous membranes). Nanoparticles formed from bioadhesive polysaccharides may prove useful as carriers of drugs, extending their persistence in a particular environment [ 19 , 20 ]. Considering that the type of matrix affects the properties and reactivity of nanocomposites, the polysaccharides most commonly used to produce bionanocomposites can be classified according to their ionic nature: neutral (starch, agarose, pullulan, dextran), anionic (carrageenans, hyaluronic acid, heparin, furcellaran) and cationic (quaternary chitosan).…”