Polysaccharides from marine red algae Amphiroa rigida and their biomedical potential: An in-vitro study

Gopu, Mani; Selvam, K.

doi:10.1016/j.bcab.2020.101769

Cited by 18 publications

(6 citation statements)

References 49 publications

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“…However, according to our best knowledge, there is only one recent phytochemical study on this alga reporting polysaccharides. The novel polysaccharides from A. rigida (ARPS) were extracted [15] by an ultrasonication disruption (USD) and the extraction conditions were optimized by response surface methodology (RSM) combined with Box-Behnken design (BBD). Furthermore, ARPS exhibited great potential for in vitro antioxidant activity in DPPH (58.24% ± 0.65%) and diammonium salt of 2,2 -azino-bis (3-ethylbenzthiazolin-6yl) sulfonic acid (ABTS + ) scavenging (52.23% ± 0.88%) activity and also showed good antibacterial activity against Salmonella typhi.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, ARPS exhibited great potential for in vitro antioxidant activity in DPPH (58.24% ± 0.65%) and diammonium salt of 2,2 -azino-bis (3-ethylbenzthiazolin-6yl) sulfonic acid (ABTS + ) scavenging (52.23% ± 0.88%) activity and also showed good antibacterial activity against Salmonella typhi. In addition, ARPS can inhibit human breast cancer cells (MCF-7) [15]. Hence, there are some studies reporting activities of other species belonging to the genus Amphiroa such as antioxidative and matrix metalloproteinase inhibitory effects of A. dilatata [16], antimicrobial activity of unspeciated Amphiroa algae [17] and antifungal and antibacterial activities of A. bowerbankii and A. ephedraea [18].…”

Section: Introductionmentioning

confidence: 99%

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Bioprospecting of Coralline Red Alga Amphiroa rigida J.V. Lamouroux: Volatiles, Fatty Acids and Pigments

et al. 2021

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Due to the lack of phytochemical composition data, the major goals of the present study on Amphiroa rigida J.V. Lamouroux were to: (a) investigate and compare volatilome profiles of fresh and air-dried samples obtained by headspace solid-phase microextraction (HS-SPME) and hydrodistillation (HD) followed by gas chromatography and mass spectrometry (GC/MS) analysis; (b) determine fatty acids profile by gas chromatography with flame ionization detector (GC-FID); (c) obtain the pigment profiles of semipurified extracts by high performance liquid chromatography (HPLC) and (d) evaluate the antioxidant and antimicrobial activities of its less polar fractions. The comparison of headspace of fresh (FrAr) and air-dried (DrAr) samples revealed many similarities regarding the presence and abundance of the major (heptadecane and pentadecane) and minor compounds. The hydrodistillate (HD) of DrAr profile was quite different in comparison to HD-FrAr. The predominant compound in HD-FrAr was (E)-phytol. In HD-DrAr, its percentage was approximately one-half reduced, but the abundance of its degradation product phytone and of unsaturated and oxygenated compounds increased indicating more intense fatty acid decomposition and oxidation during drying. The fatty acid determination revealed that the most dominant was palmitic acid (42.86%) followed by eicosapentaenoic acid (19.14%) and stearic acid (11.65%). Among the pigments, A. rigida contained fucoxanthin (0.63 mg g−1 of dry fraction), lutein (5.83 mg g−1), β-carotene (6.18 mg g−1) and chlorophyll a (13.65 mg g−1). The analyzed less polar fractions of A. rigida exhibited antioxidant scavenging activity with diammonium salt of 2,2′-azino-bis (3-ethylbenzthiazolin-6-yl) sulfonic acid (ABTS) assay up to 3.87 mg g−1 trolox equivalents (TE), and with the oxygen radical absorbance capacity (ORAC) assay up to 825.63 μmol g−1 TE (with carotenoids as the major contributors).

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Bioprospecting of Coralline Red Alga Amphiroa rigida J.V. Lamouroux: Volatiles, Fatty Acids and Pigments

et al. 2021

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“…Also, fucoidan from P. pavonica reduced SPC-A-1 tumor weight up to 50% at 40 mg/kg and increased apoptosis rates up to 40% with 300 mg/mL. In addition, this fucoidan extract showed inhibition against the proliferation of HeLa cells (IC 50 = 1.059 µg/mL) (Arunkumar et al 2021), whereas SP obtained from A. rigida had significant anticancer activity against breast cancer BCCL cells (IC 50 = 40 µg/mL) (Gopu and Selvam 2020). In a recent study exploring the use of fucoidan nanoparticles, it was reported that found their IC 50 (20 µg/mL) against PANC-1 cells was 2.3 folds lower than fucoidan extracts (IC 50 = 53 µg/mL) (Table 4).…”

Section: Antitumormentioning

confidence: 93%

Seaweed polysaccharides: Emerging extraction technologies, chemical modifications and bioactive properties

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García-Oliveira

et al. 2021

Critical Reviews in Food Science and Nutrition

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“…Studies have shown that this process has a potent antioxidation ability of up to 92.5% DPPH equivalent, making it valuable in the food and pharmaceutical industries. Gopu and Selvam [148] extracted Amphiroa rigida, an algae strain, using ultrasound to produce a powerful antioxidant. Given that the developed ARPS can scavenge DPPH and ABTS, it was determined that it also has strong antioxidant effects.…”

Section: Antioxidantmentioning

confidence: 99%

An Overview of Green Bioprocessing of Algae-Derived Biochar and Biopolymers: Synthesis, Preparation, and Potential Applications

et al. 2023

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Algae have the potential to be used as a feedstock for the synthesis of valuable compounds and biofuels. In addition, algal waste can be further transformed into biofuel, biogas, and biochar using different thermochemical processes such as microwave pyrolysis, pyrolysis, torrefaction, and hydrothermal conversion. Due to its high specific surface area, rapid electron transport, and graphitic carbon structure, algal biochar carbonized at high temperatures has shown outstanding performance for applications as CO2 adsorbents, supercapacitors, and persulfate activation. Due to the combination of various functional groups and porous structures, the algae biomass pyrolysis at a moderate temperature produced high-quality biochar that shows high performance in terms of pollutant removal, while low-temperature pyrolysis produces coal fuel from algae via torrefaction. Over time, there have been exponentially more petroleum-based polymers created that have harmful impacts on both humans and the environment. As a result, researchers are becoming more interested in algae-based biopolymers as a potential alternative strategy for establishing a sustainable circular economy globally. The advantages of microalgal biopolymer over other feedstocks are its capacity to compost, which provides greenhouse gas credits, its quick growth ability with flexibility in a variety of settings, and its ability to minimize greenhouse gas emissions.

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Polysaccharides from marine red algae Amphiroa rigida and their biomedical potential: An in-vitro study

Cited by 18 publications

References 49 publications

Bioprospecting of Coralline Red Alga Amphiroa rigida J.V. Lamouroux: Volatiles, Fatty Acids and Pigments

Bioprospecting of Coralline Red Alga Amphiroa rigida J.V. Lamouroux: Volatiles, Fatty Acids and Pigments

Seaweed polysaccharides: Emerging extraction technologies, chemical modifications and bioactive properties

An Overview of Green Bioprocessing of Algae-Derived Biochar and Biopolymers: Synthesis, Preparation, and Potential Applications

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