Polysomnography and antidiuretic hormone secretion pattern in children with primary nocturnal enuresis

Hamed, Hanan; Al-Aziz, Amany M. Abd; Motawie, Ayat A.; Fatouh, Amany; Awad, Mona; Afifi, Lamia

doi:10.4103/1110-1083.170658

Cited by 5 publications

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“…15 There are conflicting results from studies assessing sleep using polysomnography in children with nocturnal enuresis as some studies have reported that the polysomnography results of children with nocturnal enuresis were similar to those of control children, whereas other studies have shown significant differences between the 2 groups. 18,19 Few studies evaluated the relationship between sleep architecture and secondary nocturnal enuresis. Therefore, we aimed to study and to evaluate the characteristics of the sleep architecture of nocturnal enuresis in epileptic children kept on valproate monotherapy.…”

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Sleep Architecture in Valproate-Induced Nocturnal Enuresis in Primary School and Preschool Children

et al. 2020

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Nocturnal enuresis is one of the side effects of valproic acid treatment, and generally underdiagnosed by clinicians. Studies reported that a variable incidence of valproic acid–induced nocturnal enuresis is 2.2% to 24% with unclear explanations of the reasons behind valproic acid–induced nocturnal enuresis. A retrospective study was carried out on 260 children (aged 5-12 years) diagnosed with idiopathic epilepsy, treated with valproic acid to evaluate the nocturnal enuresis secondary to valproic acid, and to discuss the characteristics of their sleep architecture. Nocturnal enuresis was reported in 28 (10.7%) patients after a mean exposure time to valproate of 18.78±8.4 days. Nocturnal enuresis was significantly associated with younger age and serum level of valproate ( P = .05). The polysomnographic study suggested that the underlying mechanism may be related to impaired sleep efficiency, frequent arousals, prolonged sleep latency, snoring, or increased sleep depth which may impair a child’s ability to awaken to the sense of bladder fullness or contractions. Clinical trial registration: ClinicalTrials.gov identifiers: NCT04191863

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confidence: 99%

Sleep Architecture in Valproate-Induced Nocturnal Enuresis in Primary School and Preschool Children

et al. 2020

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Assessment of serum level of corticotropin-releasing factor in primary nocturnal enuresis

Motawie

Al-Aziz

Hamed

et al. 2017

Journal of Pediatric Urology

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A prospective study of examining physiological signals for estimating occurrence of nocturnal enuresis

Moon

Lee

et al. 2017

2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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The nocturnal enuresis is challenging due to the increased social activities of the children. This disorder significantly bothers both the children and their parents in psychological, behavioral, social, and financial manners. However, the primary treatments have limitations and further are not able to completely cure the disorder. In order to reduce pain and burdens of patients and their parents, it is important to accurately estimate when the enuretic incident occurs in advance. For the estimation, we have comprehensively investigated various studies of the nocturnal enuresis in the diverse fields. Through the investigations, we have summarized four hypotheses of the physiological signals related to the enuretic moment. In order to conquer the nocturnal enuresis, we design a preliminary framework sensing and investigating the physiological signals with the sensors. Our synthesized approach to understand and estimate the moments of the enuretic incidents can establish a foothold to complete the promising prediction system.

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Polysomnography and antidiuretic hormone secretion pattern in children with primary nocturnal enuresis

Cited by 5 publications

References 0 publications

Sleep Architecture in Valproate-Induced Nocturnal Enuresis in Primary School and Preschool Children

Sleep Architecture in Valproate-Induced Nocturnal Enuresis in Primary School and Preschool Children

Assessment of serum level of corticotropin-releasing factor in primary nocturnal enuresis

A prospective study of examining physiological signals for estimating occurrence of nocturnal enuresis

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