Polyunsaturated Fatty Acids in Human Milk

Innis, Sheila M.

doi:10.1007/978-1-4757-4242-8_5

Cited by 169 publications

(25 citation statements)

References 78 publications

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“…A similar trend was found in our study where the mothers' milk in the Chinese city of Changzhou, had a ratio of ω‐6/ω‐3 around 15, similar to that found during the third month of lactation in a rural area, north of Beijing in China, where the same ratio was 19.3 (14). The ratio of AA/DHA was much lower, in our study around 2, and only slightly lower than in the north of China and similar to that found in most recent investigations (25). It was higher than in Japan (26), and in some older studies, in which the ratio AA/DHA often was 0.5–1 (23).…”

Section: Discussionsupporting

confidence: 92%

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Fatty acid composition in breast milk and serum phospholipids of healthy term Chinese infants during first 6 weeks of life

Q³

et al. 2007

Acta Paediatrica

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Section: Discussionsupporting

confidence: 92%

“…It was higher than in Japan (26), and in some older studies, in which the ratio AA/DHA often was 0.5–1 (23). The high ratio of ω‐6/ω‐3 in recent investigations therefore mainly reflects the general dietary increase of LA (22,25). Differences in the ratios between EFA, i.e.…”

Section: Discussionmentioning

confidence: 99%

Fatty acid composition in breast milk and serum phospholipids of healthy term Chinese infants during first 6 weeks of life

Q³

et al. 2007

Acta Paediatrica

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“…Non-essential FA, such as oleic monounsaturated fatty acid (18: 1 ω-9) and palmitic saturated (16: 0 ω-7), can be endogenously synthesized and also transferred through the placenta during gestation; secreted into the maternal milk and accumulate in the brain and other organs during fetal development (Innis, 2004, 2005). Oleic fatty acid is one of the main constituents of myelin (Garbay et al, 2000); it is related to axonal growth and neuronal grouping (Medina and Tabernero, 2002).…”

Section: Introductionmentioning

confidence: 99%

Maternal Supplementation With Avocado (Persea americana Mill.) Pulp and Oil Alters Reflex Maturation, Physical Development, and Offspring Memory in Rats

et al. 2019

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Avocado (Persea americana Mill.) is an oleaginous fruit source of fatty acids with high levels of neuroprotective phytocomplexes. The objective of this study was to evaluate the development of reflex and somatic maturation, fatty acid profiles in the brain, and memory in different stages of life in the offspring of dams supplemented with avocado pulp and oil during gestation and lactation. The dams were randomly divided into three groups (n = 15 pups/group), and recieved by gavage supplementation: control group (CG)–distilled water; Avocado Oil (AO)−3,000 mg avocado oil/kg animal weight, and Avocado Pulp (AP)−3,000 mg avocado pulp/kg animal weight. We performed the following tests: Analysis of Somatic Development and Ontogeny of Postnatal Reflex (T0 to T21), the Open Field Habituation Test and the Object Recognition Test (ORT) in the adolescent (T45) and adult (T90) phases. The cerebral fatty acids content was evaluated at times T0, T21, T45, and T90. The results were analyzed using the statistical program GraphPad Prism and significant statistics were considered when p < 0.05. Acceleration of reflex maturation and reflex ontogeny was observed in the offspring of AO and AP fed dams, with the results being more pronounced in the pulp fed group (p < 0.05). All groups presented a decrease in the ambulation parameter in the second exposure to the Open Field Habituation Test, at T45 and T90 (p < 0.05). In the ORT, the AO and AP offspring presented memory improvements in the short and long term in the adult and adolescent phases (p < 0.05). The results of the brain fatty acid profiles presented higher polyunsaturated fatty acids (PUFA) content in the AO and AP groups at T21, T45, and T90. The docosahexaenoic fatty acid (DHA) content was higher at T21 (AO and AP), at T45 (AO and AP), and at T90 (AP) (p < 0.05). The arachidonic acid (ARA) content was higher at T45 (AO and AP), and at T90 (AO) (p < 0.05). Maternal supplementation with avocado oil and pulp anticipates reflex maturation and somatic postnatal development, and improves memory during the adolescent and adult phases.

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“…Scientific advances in recent decades have made it clear that maternal diet fat quality, specifically the types of fatty acids, is a significant determinant of the fatty acids transferred across the placenta and secreted in milk (Innis 2004(Innis , 2005Jensen 1999). This in turn can lead to profound changes in the fatty acids accumulated in fetal and infant tissues, which is not without consequence.…”

Section: Dr Sheila Innis Advances In Dietary Fats and Nutrition -Mamentioning

confidence: 98%

Proceedings from the 2013 Canadian Nutrition Society Conference on Advances in Dietary Fats and Nutrition

Holub

Mutch

Pierce

et al. 2014

Appl. Physiol. Nutr. Metab.

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The science of lipid research continues to rapidly evolve and change. New knowledge enhances our understanding and perspectives on the role of lipids in health and nutrition. However, new knowledge also challenges currently held opinions. The following are the proceedings of the 2013 Canadian Nutrition Society Conference on the Advances in Dietary Fats and Nutrition. Content experts presented state-of-the-art information regarding our understanding of fish oil and plant-based n-3 polyunsaturated fatty acids, nutrigenomics, pediatrics, regulatory affairs, and trans fats. These important contributions aim to provide clarity on the latest advances and opinions regarding the role of different types of fats in health.

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Polyunsaturated Fatty Acids in Human Milk

Cited by 169 publications

References 78 publications

Fatty acid composition in breast milk and serum phospholipids of healthy term Chinese infants during first 6 weeks of life

Fatty acid composition in breast milk and serum phospholipids of healthy term Chinese infants during first 6 weeks of life

Maternal Supplementation With Avocado (Persea americana Mill.) Pulp and Oil Alters Reflex Maturation, Physical Development, and Offspring Memory in Rats

Proceedings from the 2013 Canadian Nutrition Society Conference on Advances in Dietary Fats and Nutrition

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