Polyunsaturated fatty acids reduce levels of LDL and triglycerides in patients with heterozygous familial hypercholesterolemia

Hande, Liv Nesse; Kjellmo, Christian Abendstein; Pettersen, Kristin; Thunhaug, Hilde; Enebakk, Terje; Hovland, Anders; Lappegård, Knut Tore

doi:10.1016/j.atherosclerosis.2018.06.542

Cited by 2 publications

(1 citation statement)

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“…Step 1 diet guideline recommends a fat intake with a balanced (1:1:1) composition of SFAs/MUFAs/PUFAs [38]. A high intake of dietary PUFAs reduces LDL-C (low-density lipoprotein cholesterol) and triglyceride plasma levels [39]. A careful review of numerous reports in the literature highlighted the importance of SFAs/MUFAs/PUFAs balance for generating the best LDL-C/HDL-C (high-density lipoprotein cholesterol) ratio in human serum [40].…”

Section: Fatty Acid Composition and Lipid Quality Indicesmentioning

confidence: 99%

Fats Extracted from Oil Press Cakes, Fish Meat, and Chicken Hearts as Potential CoQ10 Supplements

Semeniuc,

Mandrioli,

Podar

et al. 2024

Waste Biomass Valor

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Coenzyme Q10 (CoQ10) is a liposoluble compound naturally occurring in plant and animal cells, with some bene ts for health, mainly due to its antioxidant properties. The food industry gives large quantities of by-products and waste; these could be used to recover the natural form of CoQ10, which has a higher bioavailability than synthetic. The Folch method was used in this study to extract and characterise the fats from some food by-products (oil press cakes of rapeseed, sun ower, pumpkin, linseed, walnut, and hempseed) and waste ( sh meat and chicken hearts), previously identi ed as sources of CoQ10, for potential uses as dietary supplements. The highest CoQ10 content was found in fats extracted from chicken hearts-CH (2041.74 µg/g) and pumpkin press cakes-PPC (661.40 µg/g). Both fats are triglycerides but have a low CVD risk (AI values below the recommended limit). CH fat is dominated by oleic acid (n-9) and PPC fat by linoleic acid (n-6). PUFAs/MUFAs ratio is above the recommended minimum in both fats; however, the n-6/n-3 PUFAs ratio in CH fat exceeds the maximum value. They also contain tocopherols (PPC-138.09 µg/g and CH-54.22 µg/g) that, along with CoQ10, give them antioxidant properties; therefore, they meet the criteria of a food supplement. HighlightsThe highest CoQ10 content is in chicken hearts and pumpkin press cake fats Both fats are triglycerides but have AI values below the recommended limit PUFAs/MUFAs ratio is above the recommended minimum in both fatsThe n-6/n-3 PUFAs ratio in fat from chicken hearts exceeds the maximum value Their antioxidant properties are also due to the presence of tocopherols

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Section: Fatty Acid Composition and Lipid Quality Indicesmentioning

confidence: 99%

Fats Extracted from Oil Press Cakes, Fish Meat, and Chicken Hearts as Potential CoQ10 Supplements

Semeniuc,

Mandrioli,

Podar

et al. 2024

Waste Biomass Valor

View full text Add to dashboard Cite

show abstract

Fats extracted from oil press cakes, fish meat, and chicken hearts as potential CoQ10 supplements

Semeniuc,

Mandrioli,

Podar

et al. 2023

Preprint

View full text Add to dashboard Cite

Coenzyme Q10 (CoQ10) is a liposoluble compound naturally occurring in plant and animal cells, with some benefits for health, mainly due to its antioxidant properties. The food industry gives large quantities of by-products and waste; these could be used to recover the natural form of CoQ10, which has a higher bioavailability than synthetic. The Folch method was used in this study to extract and characterise the fats from some food by-products (oil press cakes of rapeseed, sunflower, pumpkin, linseed, walnut, and hempseed) and waste (fish meat and chicken hearts), previously identified as sources of CoQ10, for potential uses as dietary supplements. The highest CoQ10 content was found in fats extracted from chicken hearts-CH (2041.74 µg/g) and pumpkin press cakes-PPC (661.40 µg/g). Both fats are triglycerides but have a low CVD risk (AI values below the recommended limit). CH fat is dominated by oleic acid (n-9) and PPC fat by linoleic acid (n-6). PUFAs/MUFAs ratio is above the recommended minimum in both fats; however, the n-6/n-3 PUFAs ratio in CH fat exceeds the maximum value. They also contain tocopherols (PPC-138.09 µg/g and CH-54.22 µg/g) that, along with CoQ10, give them antioxidant properties; therefore, they meet the criteria of a food supplement.

show abstract

Polyunsaturated fatty acids reduce levels of LDL and triglycerides in patients with heterozygous familial hypercholesterolemia

Cited by 2 publications

References 0 publications

Fats Extracted from Oil Press Cakes, Fish Meat, and Chicken Hearts as Potential CoQ10 Supplements

Fats Extracted from Oil Press Cakes, Fish Meat, and Chicken Hearts as Potential CoQ10 Supplements

Fats extracted from oil press cakes, fish meat, and chicken hearts as potential CoQ10 supplements

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