Polyurethane in Urological Practice

Cauda, Valentina; Cauda, F

doi:10.5772/36408

Cited by 2 publications

(6 citation statements)

References 26 publications

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“…Therefore, we account that urine flow dynamics is a more complex mechanism than only a difference in stent and ureter diameters, as observed in the work of Clavica et al We observed indeed that the used procedures here lead to results (i.e., encrustation compositions and morphologies of the crystals found on the stent surfaces) similar to what reported in other in vitro case studies . In addition, the obtained data seem to well simulate the behavior of what reported in real‐case in vivo studies and in particular for even longer indwelling times of the stents . This fact supports the assumption that using artificial urine solutions almost saturated with inorganic compounds can simulate even longer indwelling time periods in vivo with respect to what experienced in vitro .…”

Section: Discussionsupporting

confidence: 90%

“…13,28 In addition, the obtained data seem to well simulate the behavior of what reported in real-case in vivo studies and in particular for even longer indwelling times of the stents. 14,15,17 This fact supports the assumption that using artificial urine solutions almost saturated with inorganic compounds can simulate even longer indwelling time periods in vivo with respect to what experienced in vitro.…”

Section: Wetting Behaviorsupporting

confidence: 71%

“…The stents were cut both perpendicular and parallel to their axis in order to obtain cross sections or plan views, respectively, of the inner and outer surfaces, as already reported in Ref. .…”

Section: Methodsmentioning

confidence: 99%

“…11,12 Other coatings reported to effectively decrease the biofilm and surface encrustation are aliphatic polyether urethanes (Tecoflex V R ) coated with polyvinylpyrrolidone-iodine, tested in in vitro experiments, 13 as well as heparin 14 or plasma-deposited diamond-like amorphous carbon coatings 15,16 on polyurethane stents, characterized after prolonged in vivo indwelling. 17 In the present article, it is reported, for the first time to the authors' knowledge, the evaluation of three different stent materials after long-term (up to 6 months) in vitro indwelling in an ad hoc model. In addition, a comparison of the performances in preventing inorganic encrustations is presented between two different polyurethane stents, one of them showing a hydrophilic coating with hydrogel (Hydromer V R ), and a water-mediated swelling chitosan (CHI) stent.…”

Section: Introductionmentioning

confidence: 94%

“…The water entrapment in the hydrogel matrix decreases the friction coefficient and in turns reduces bacterial cell adhesion . Other coatings reported to effectively decrease the biofilm and surface encrustation are aliphatic polyether urethanes (Tecoflex ® ) coated with polyvinylpyrrolidone‐iodine, tested in in vitro experiments, as well as heparin or plasma‐deposited diamond‐like amorphous carbon coatings on polyurethane stents, characterized after prolonged in vivo indwelling …”

Section: Introductionmentioning

confidence: 99%

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Ureteral double‐J stents performances toward encrustation after long‐term indwelling in a dynamic in vitro model

et al. 2016

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Three different single-lumen double-J ureteral stents of different materials were studied and compared after the insertion into a dynamic in vitro model with sterile artificial urine up to 6 months. The aim was to evaluate, at selected time steps of 1, 3, and 6 months, the material performances of the stents in preventing the formation of inorganic encrustations. Morphological, compositional, and qualitative analyses were carried out both before stent insertion and after stent permanence for the different time steps, showing an increasing level of encrustation which remains particularly low in the case of two polyurethane stents. Mechanical tests show that both the polyurethane stents and the chitosan one do not decrease the tensile strength after 6 months of indwelling. Evaluation of the wetting behavior of the stent outer surfaces indicates a hydrophilic behavior in most of the cases, which is generally preserved after immersion in artificial urine for the different time steps. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2244-2253, 2017.

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Section: Discussionsupporting

confidence: 90%

Section: Wetting Behaviorsupporting

confidence: 71%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

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Ureteral double‐J stents performances toward encrustation after long‐term indwelling in a dynamic in vitro model

et al. 2016

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Coatings for Urinary Stents: Current State and Future Directions

et al. 2022

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Urinary stent coatings are a strategy to tackle certain complications associated with the use of biomaterials. The latest innovations in surface coatings focused on the prevention of those problems, thus reducing further costs with treatments. Urinary stents associated symptoms, infections and encrustation are considered the major challenges, and, in an attempt to prevent such morbidity, several strategies were developed. Hence, coatings have been designed to improve quality of life for patients, reducing the friction, inhibiting uropathogens survival or attachment on stents, and avoiding the deposition of urinary crystals that triggers encrustation. Currently for ureteral stents, hydrophilic and diamond-like carbon coatings are commercial options associated with an enhanced performance of devices, comparing with uncoated ones. These commercially available approaches are all anti-adhesive coatings, and, in the general overview, this type of strategy appears to be a superior alternative than bactericidal coatings. Designs that trigger uropathogen death are usually associated with higher toxicity, and, in some cases, it can even favor the development of microbial resistance, which can hamper the infection treatment. With the present knowledge about antimicrobial mechanisms and inspired by nature, more cutting-edge alternatives, able to confer antimicrobial properties to the inner and outer parts of stents, will surely appear.

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Polyurethane in Urological Practice

Cited by 2 publications

References 26 publications

Ureteral double‐J stents performances toward encrustation after long‐term indwelling in a dynamic in vitro model

Ureteral double‐J stents performances toward encrustation after long‐term indwelling in a dynamic in vitro model

Coatings for Urinary Stents: Current State and Future Directions

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