Polyvinyl alcohol functionalized cobalt ferrite nanoparticles for biomedical applications

Salunkhe, A.B.; Khot, Vishwajeet M.; Thorat, Nanasaheb D.; Phadatare, M.R.; Sathish, Clastin I.; Dhawale, Dattatray S.; Pawar, S.H.

doi:10.1016/j.apsusc.2012.10.073

Cited by 192 publications

(73 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Despite the promising properties of this material, its use in biomedical application is debated due to the presence of cobalt. While for uncoated cobalt ferrite NPs a non-negligible toxicity is reported in the literature [13,14], the coating with silica or polymers strongly improves their biocompatibility [13,15,16]. However, a low residual toxicity is often still present, depending on the cellular line investigated and on the concentration of the NPs used [17,18].…”

Section: Introductionmentioning

confidence: 93%

Influence of cobalt doping on the hyperthermic efficiency of magnetite nanoparticles

Fantechi

Innocenti

Albino

et al. 2015

Journal of Magnetism and Magnetic Materials

109

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 93%

Influence of cobalt doping on the hyperthermic efficiency of magnetite nanoparticles

Fantechi

Innocenti

Albino

et al. 2015

Journal of Magnetism and Magnetic Materials

109

View full text Add to dashboard Cite

“…These properties, along with its great physical and chemical stabilities, make CoFe 2 O 4 nanoparticles suitable for many practical applications such as magnetic fluid [1,2], drug delivery [3], high density digital recording disks and magneto-optical recording media [4,5,6]. The chemical processes used to prepare cobalt ferrite powder are very diverse from the using of the polymeric precursor [7,8], wet chemical route [9,10,11], and chemical coprecipitation techniques [12,13,14]. The sol-gel technique is one of the most proper methods for the synthesis of homogeneous nanocrystalline materials.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of single-phase cobalt ferrite nanoparticles via a novel EDTA/EG precursor-based route and their magnetic properties

Avazpour

Khajeh

Toroghinejad

et al. 2015

Journal of Alloys and Compounds

View full text Add to dashboard Cite

“…The saturation magnetization (M s ), remanent magnetization (M r ), coercivity (H c ) and loop squareness ratio (M r /M s ) of the bare and coated sample are summarized in Table 1. It can be seen that the M s of the coated sample (29 emu/g) is smaller compared to the uncoated sample (34 emu/g) at an applied field of ±20,000 G at 300 K. The reduction in magnetization for the coated sample may be attributed to the presence of non-magnetic silica layer on the surface of NPs which reduces the particle-particle interaction and lowers the exchange coupling energy which in turn reduces the magnetization [39]. The reduction in magnetization might also be due to the lesser amount of magnetic substance per gram in the silica coated sample compared with the bare sample [40].…”

Section: Magnetic Studies Of Bare and Silica Coated Lnmo Samplementioning

confidence: 95%

Magneto-Structural and Antimicrobial Properties of Sodium Doped Lanthanum Manganite Magnetic Nanoparticles for Biomedical Applications: Influence of Silica Coating

Ehi-Eromosele

Olugbuyiro

Edobor-Osoh

et al. 2018

JBBBE

View full text Add to dashboard Cite

Abstract. Coating of magnetic nanoparticles (MNPs) is usually a requirement prior to their utilization in biomedical applications. However, coating can influence the magneto-structural properties of MNPs thereby imparting their applications. The present work highlights the combustion synthesis of Na-doped lanthanum manganites (LNMO) and the influence of silica coatings on the magneto-structural properties, colloidal stability and antimicrobial properties of LNMO MNPs with their biomedical applications in mind. The crystalline perovskite structure was the same both for the bare and silica coated LNMO samples while there was a slight increase in crystallite size after coating. The FTIR spectral analysis, reduction in agglomeration of the particles and the elemental composition of the coated nanoparticles confirmed the presence of silica. The magnetization values of 34 emu/g and 29 emu/g recorded for bare and coated LNMO samples, respectively show that LNMO MNPs retained its ferromagnetic behaviour after silica coating. The pH dependent zeta potentials of the coated sample is -22.20 mV at pH 7.4 (physiological pH) and -18 mV at pH 5.0 (cell endosomal pH). Generally, silica coating reduced the antibacterial activity of the sample except for Bacillus spp where the antibacterial activity was the same with the bare sample. These results showed that while silica coating had marginal effect on the crystalline structure, size and magnetization of LNMO MNPs, it reduced the antibacterial activity of LNMO MNPs and enhanced greatly the colloidal stability of LNMO nanoparticles. IntroductionThe discovery of colossal-magnetoresistance (CMR) effect in doped mixed valent perovskite manganese oxides A 1-x B x MnO 3 (A = rare earth element, B = divalent or monovalent element) has elicited intensive research, over the years, in which these materials have been studied for basic and potential applications. The partial replacement of A element with B element leads to the appearance of mixed-valence state Mn 3+ /Mn 4+ resulting in the emergence of unique physical properties like CMR, ferromagnetic metal-antiferromagnetic insulator transition around the Curie temperature, Tc, which has been explained by the Zener double exchange mechanism [1][2][3]. Large Tc as well as large magnetoresistance values near room temperature has been observed in Na-doped lanthanum manganites (LNMO) making them to be promising functional materials in medicine, information technologies and low-temperature thermal engineering [4,5].Amongst other applications, magnetic nanoparticles (MNPs) have attracted intense research for their biomedical applications [6,7]. The unique physico-chemical properties of MNPs coupled with their sensing, moving and heating capabilities have made them to be amenable in biomedical applications such as targeted drug delivery, magnetic resonance imaging, magnetofection and hyperthermia [8][9][10][11][12] Since MNPs have large surface-to-volume ratio, they tend to aggregate to reduce their high surface energies [13]. Also, they can be e...

show abstract

Polyvinyl alcohol functionalized cobalt ferrite nanoparticles for biomedical applications

Cited by 192 publications

References 30 publications

Influence of cobalt doping on the hyperthermic efficiency of magnetite nanoparticles

Influence of cobalt doping on the hyperthermic efficiency of magnetite nanoparticles

Synthesis of single-phase cobalt ferrite nanoparticles via a novel EDTA/EG precursor-based route and their magnetic properties

Magneto-Structural and Antimicrobial Properties of Sodium Doped Lanthanum Manganite Magnetic Nanoparticles for Biomedical Applications: Influence of Silica Coating

Contact Info

Product

Resources

About