Poor Acceptance Rate for Semen Donors to a Private Cryobank in Nigeria

Abstract

A retrospective analysis of sixty one prospective donors who visited the cryobank in person from August 1999 to December 2001 was done. The study evaluated the acceptance rate of prospective semen donors and semen characteristics in order to assess the fertility potential of the supposedly normal population of young men. The outcome of the various screening processes--history taking, infection screening, blood grouping and Hb genotype assessment, semen analyses (pre-freeze and post-thaw), and post-quarantine (six months after production of last sample) infection--was analysed. Out of the 61 enquiries, 9 (14.8%) donors were recruited, 7 (77.8%) of whom were less than 25 years old. Fourteen (22.9%) donors had sperm concentrations greater than 60' 10(6) ml, 31 (50.8%) had motility greater than 60% and 17 (27.8%) had normal forms greater than 30%. Six (9.8%) of the donors were unable to masturbate and thus were disqualified, while only one donor (6.1%) failed to show up for a re-test after the completion of the quarantine period. Twenty one (38.2%) donors had low semen values based on the WHO reference value. We conclude that a high proportion of prospective semen donors may have suboptimal semen parameters, and that using strict criteria, poor acceptance rates for donors is observed in a semen donation programme.

An analysis of the outcome of 11 712 men applying to be sperm donors in Denmark and the USA

“…When this figure is used as the numerator instead, our final acceptance rate increases slightly to 7.40%, which is still remarkably low in comparison. The recruitment rates for other countries include: 14.8% in Nigeria ( Akinrinola et al , 2003 ), 32% in the USA ( Schroeder-Jenkins and Rothmann 1989 ), and 33.2% in China ( Ping et al , 2011 ). Liu et al (2021) suggested that these country differences in the final acceptance rate may be caused by different recruitment criteria in operation at each location.…”

Diurnal rhythm of human semen quality: analysis of large-scale human sperm bank data and timing-controlled laboratory study

“…Our findings may have important clinical significance. Only a minority (15–30%) of the volunteers visiting HSBs could meet the strict screening standards ( Akinrinola et al , 2003 ; Paul et al , 2006 ; Jie et al , 2011 ; Guan et al , 2014 ). Most of the ineligible candidates were rejected owing to unfavorable semen quality, especially inadequate sperm count and sperm motility ( Paul et al , 2006 ; Jie et al , 2011 ; Guan et al , 2014 ; Zhang et al , 2019 ).…”