Poor medication adherence in diabetes: What's the problem?

Polonsky, William H.

doi:10.1111/1753-0407.12306

Cited by 15 publications

(14 citation statements)

References 13 publications

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“…This review provides evidence to support the argument in a recent editorial that 'patients who are not adhering to prescribed medication regimens are, in most cases, trying to make the healthiest choice they can' [32]. The potential to capitalize on motivation and to work with patients to direct energy towards more beneficial behaviours is also worth considering.…”

Section: Discussionmentioning

confidence: 80%

Perceptions and experiences of taking oral medications for the treatment of Type 2 diabetes mellitus: a systematic review and meta‐synthesis of qualitative studies

et al. 2016

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AimsTo explore patients' perceptions and experiences of taking oral medications for the pharmacological management of Type 2 Diabetes Mellitus (Type2DM). MethodsCinahl, EMBASE, Medline and PsycINFO databases were searched in 2014 to identify qualitative studies exploring patients' perceptions or experiences of taking medications for the management of Type2DM. Key concepts and themes were extracted and synthesised using meta-ethnography. ResultsEight studies were included. Primary study findings were synthesised to develop three higher order ConclusionsMedication taking for Type2DM is a unique adherence context, which requires the development of condition-specific interventions. Our findings indicate patients understand the need for medications but adjust dosage and timing in their daily lives. Our review suggests providers should acknowledge patient preferences in the development of management strategies and highlights an opportunity to direct the motivation evident in patients' experimentation towards potentially more beneficial medication taking behaviours.3

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Section: Discussionmentioning

confidence: 80%

Perceptions and experiences of taking oral medications for the treatment of Type 2 diabetes mellitus: a systematic review and meta‐synthesis of qualitative studies

et al. 2016

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“…The American Diabetes Association (ADA) estimated that patients with diabetes spent 27% ($3,734 per patient in 2012) of direct medical costs for outpatient medications and supplies [3]. The high cost of diabetes care is associated with medication non-adherence [4–6], which results in poor clinical outcomes [7,8]. Patients with diabetes often have comorbidities that require medications in addition to oral and injectable diabetes medications.…”

Section: Introductionmentioning

confidence: 99%

Cost-related medication non-adherence among U.S. adults with diabetes

Kang

Lobo

Kim

2018

Diabetes Research and Clinical Practice

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Aims: To examine factors that affect cost-related medication non-adherence (CRN), defined as taking medication less than as prescribed because of cost, among adults with diabetes and to determine their relative contribution in explaining CRN. Methods: Behavioral Risk Factor Surveillance System data for 2013–2014 were used to identify individuals with diabetes and their CRN. We modeled CRN as a function of financial factors, regimen complexity, and other contextual factors including diabetes care, lifestyle, and health factors. Dominance analysis was performed to rank these factors by relative importance. Results: CRN among U.S. adults with diabetes was 16.5%. Respondents with annual income <$50,000 and without health insurance were more likely to report CRN, compared to those with income ≥$50,000 and those with insurance, respectively. Insulin users had 1.24 times higher risk of CRN compared to those not on insulin. Contextual factors that significantly affected CRN included diabetes care factors, lifestyle factors, and comorbid depression, arthritis, and COPD/asthma. Dominance analysis showed health insurance was the most important factor for respondents <65 and depression was the most important factor for respondents ≥65. Conclusions: In addition to traditional risk factors of CRN, compliance with annual recommendations for diabetes and healthy lifestyle were associated with lower CRN. Policies and social supports that address these contextual factors may help improve CRN.

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“…PMA is associated with escalation of treatment costs and clinical outcomes. 11 Patient having depression, blind beliefs and medicinal costs were attributed to PMA in Polonsky studies. 11 In our study the main factors which led to poor adherence were unknown reasons, follow-up irregularity, noncompliance for adverse reactions and medication ignorance.…”

Section: Discussionmentioning

confidence: 99%

“…11 Patient having depression, blind beliefs and medicinal costs were attributed to PMA in Polonsky studies. 11 In our study the main factors which led to poor adherence were unknown reasons, follow-up irregularity, noncompliance for adverse reactions and medication ignorance. Polypharmacy and addiction to smoking and alcohol were also minor factors which influenced the outcome of our study.…”

Section: Discussionmentioning

confidence: 99%

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Pattern of drug utilization and factors influencing long term blood sugar control among diabetics in a tertiary care hospital- an observational study

Prasada

Patil

Vishwanath

et al. 2017

Int J Basic Clin Pharmacol

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INTRODUCTIONDiabetes mellitus is a metabolic disorder of multiple etiologies, characterized by chronic hyperglycemia.1 It has emerged as a major health problem in India.2 It is fast gaining the status of potential epidemic in India with more than 62 million diabetic individuals currently diagnosed with the disease. This number is expected to increase to 79.4 million by 2030. 3 The crude prevalence rate in urban areas of India is apparently 9% and in rural ABSTRACT Background: To study the Pattern of drug prescribing, utilization, analyse effectives of different therapies and factors influencing medication failure and adherence to treatment among diabetics. Methods:The clinical study was conducted in JJM Medical College and Karuna Trust, Davangere, Karnataka. The patients with diabetes as diagnosed by consultant physician were observed for the pattern of blood glucose control. The fasting blood glucose of the patients were recorded at the end of 1st month, 6th month and 12 th month of their treatment period. The study period was from June 2012 till August 2014. The study was conducted after institutional ethical clearance and informed consent was taken from all the patients. The pattern of drugs prescribed for the patients were also analysed. The pattern of control among patients with co morbidities were also analysed using paired sample t test. Results:The results showed that the prescribed drugs were able to control the blood glucose levels of the patients. The percentage of patients with FBS in controlled, mild to moderate control and uncontrolled group were 21%, 33.3% and 45.5% in early treatment period and 36%, 40.9%, and 22.7% after one year treatment period (Significant p value). The pattern of drug utilization showed that the most commonly used drugs were the combination of pioglitazone+glimipride+metformin (19%), combination of glibenclamide+ metformin (18%), only insulin (9%), combination of glimipride+metformin (8%) and combination of gliclazide+metformin (5%). Conclusions:The results show that the intervention by the consultant physician was successful in controlling the blood sugar levels and the reasons for failure of treatment and adherence to treatment were helpful for further treatment of patients. Further such studies in a larger sample will help the consultants in their treatment methods.

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Poor medication adherence in diabetes: What's the problem?

Cited by 15 publications

References 13 publications

Perceptions and experiences of taking oral medications for the treatment of Type 2 diabetes mellitus: a systematic review and meta‐synthesis of qualitative studies

Perceptions and experiences of taking oral medications for the treatment of Type 2 diabetes mellitus: a systematic review and meta‐synthesis of qualitative studies

Cost-related medication non-adherence among U.S. adults with diabetes

Pattern of drug utilization and factors influencing long term blood sugar control among diabetics in a tertiary care hospital- an observational study

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